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anti-LGALS9 antibody :: anti-Human Galectin 9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS820334
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Galectin 9 (LGALS9), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-Galectin 9 Antibody

 Product Synonym Names    Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21
 Product Gene Name   

anti-LGALS9 antibody

[Similar Products]
 Antibody/Peptide Pairs    Galectin 9 peptide (MBS823617) is used for blocking the activity of Galectin 9 antibody (MBS820334)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601879
 3D Structure    ModBase 3D Structure for O00182
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 Clonality    Polyclonal
 Species Reactivity    Human
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 Specificity    Recognizes endogenous levels of Galectin 9 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Source    Rabbit
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Galectin 9. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-LGALS9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LGALS9 antibody

   Rabbit polyclonal antibody to Galectin 9
 Applications Tested/Suitable for anti-LGALS9 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

 Application Notes for anti-LGALS9 antibody    WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/ICC (1/100 - 1/500)
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 Western Blot (WB) of anti-LGALS9 antibody    Western blot analysis of Galectin 9 expression in THP1 (A), mouse spleen (B) whole cell lysates.
anti-LGALS9 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-LGALS9 antibody    Immunohistochemical analysis of Galectin 9 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-LGALS9 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence/Immunocytochemistry (IF/ICC) of anti-LGALS9 antibody    Immunofluorescent analysis of Galectin 9 staining in THP1 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 degree C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
anti-LGALS9 antibody Immunofluorescence/Immunocytochemistry (IF/ICC) (ICC) image
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NCBI/Uniprot data below describe general gene information for LGALS9. It may not necessarily be applicable to this product.
 NCBI GI #    102469694
 NCBI GeneID    3965
 NCBI Accession #    NP_002299.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002308.3 [Other Products]
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 UniProt Primary Accession #    O00182 [Other Products]
 UniProt Secondary Accession #    O14532; O75028; Q3B8N1; Q53FQ0; Q9NQ58; A7VJG6 [Other Products]
 UniProt Related Accession #    O00182 [Other Products]
 Molecular Weight    35,888 Da
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 NCBI Official Full Name    galectin-9 isoform short
 NCBI Official Synonym Full Names    lectin, galactoside-binding, soluble, 9
 NCBI Official Symbol    LGALS9 [Similar Products]
 NCBI Official Synonym Symbols   
HUAT; LGALS9A
[Similar Products]
 NCBI Protein Information    galectin-9; gal-9; ecalectin; galectin 9; tumor antigen HOM-HD-21; urate transporter/channel protein
 UniProt Protein Name    Galectin-9
 UniProt Synonym Protein Names   
Ecalectin; Tumor antigen HOM-HD-21
 Protein Family    Galectin
 UniProt Gene Name    LGALS9 [Similar Products]
 UniProt Synonym Gene Names    Gal-9 [Similar Products]
 UniProt Entry Name    LEG9_HUMAN
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 NCBI Summary for LGALS9    The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LGALS9    galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytoplasm

Molecular Function: signal transducer activity; galactose binding; carbohydrate binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction
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 Research Articles on LGALS9    1. Gal-9 production is induced by influenza virus infection in humans, making it a potential disease biomarker.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LGALS9 antibodyDiseases associated with anti-LGALS9 antibody
 Reference Product  PubMed Publications
 HAVCR2 antibody  >45 publications with LGALS9 and HAVCR2
 TLR3 antibody  >2 publications with LGALS9 and TLR3
 TNFSF10 antibody  >1 publications with LGALS9 and TNFSF10
 IRF7 antibody  >1 publications with LGALS9 and IRF7
 IL1B antibody  >1 publications with LGALS9 and IL1B
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >35 publications with LGALS9 and Inflammation
 Disease Models, Animal Antibodies  >12 publications with LGALS9 and Disease Models, Animal
 Liver Diseases Antibodies  >12 publications with LGALS9 and Liver Diseases
 Hepatitis Antibodies  >10 publications with LGALS9 and Hepatitis
 Necrosis Antibodies  >9 publications with LGALS9 and Necrosis
 Liver Neoplasms Antibodies  >6 publications with LGALS9 and Liver Neoplasms
 Kidney Diseases Antibodies  >4 publications with LGALS9 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with LGALS9 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >4 publications with LGALS9 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >4 publications with LGALS9 and Neoplasm Metastasis
Organs/Tissues associated with anti-LGALS9 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >103 publications with LGALS9 and Blood
 Liver Antibodies  >14 publications with LGALS9 and Liver
 Kidney Antibodies  >14 publications with LGALS9 and Kidney
 Lung Antibodies  >12 publications with LGALS9 and Lung
 Intestine Antibodies  >7 publications with LGALS9 and Intestine
 Lymph Node Antibodies  >6 publications with LGALS9 and Lymph Node
 Bone Antibodies  >6 publications with LGALS9 and Bone
 Skin Antibodies  >6 publications with LGALS9 and Skin
 Brain Antibodies  >5 publications with LGALS9 and Brain
 Uterus Antibodies  >5 publications with LGALS9 and Uterus
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