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anti-Ghsr antibody :: Rabbit Ghsr Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS855570
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ghsr, Polyclonal Antibody

★Popular Item★
 Also Known As   

Ghsr Antibody

 Product Gene Name   

anti-Ghsr antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Form/Format    Lyophilized Ghsr antibody purified by peptide affinity column containing 2% BSA and 0.02% NaN3
 Concentration    100ug/200ul (lot specific)
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 Source Note    Rabbit polyclonal Ghsr (1) antibody was raised against a peptide from a peptide from near the N terminal residues of human Ghsr protein.
 Reactivity Note    Not yet tested in other species.
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-Ghsr antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-Ghsr antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-Ghsr antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-Ghsr antibody    Peptide ELISA titer: 1:1,000-1:10,000
Western blot analysis: 1:200-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
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 Testing Data of anti-Ghsr antibody    anti-Ghsr antibody Testing Data image
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 Testing Data #2 of anti-Ghsr antibody    anti-Ghsr antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for Ghsr. It may not necessarily be applicable to this product.
 NCBI GI #    34419637
 NCBI GeneID    84022
 NCBI Accession #    NP_114464.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_032075 [Other Products]
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 UniProt Related Accession #    O08725 [Other Products]
 Molecular Weight    40,963 Da
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 NCBI Official Full Name    Rattus norvegicus growth hormone secretagogue receptor (Ghsr), mRNA
 NCBI Official Synonym Full Names    growth hormone secretagogue receptor
 NCBI Official Symbol    Ghsr [Similar Products]
 NCBI Protein Information    growth hormone secretagogue receptor type 1; GHRP; GHS-R; ghrelin receptor; GH-releasing peptide receptor
 UniProt Protein Name    Growth hormone secretagogue receptor type 1
 UniProt Synonym Protein Names   
GH-releasing peptide receptor; GHRP; Ghrelin receptor
 Protein Family    Growth hormone secretagogue receptor
 UniProt Gene Name    Ghsr [Similar Products]
 UniProt Synonym Gene Names    GHS-R; GHRP [Similar Products]
 UniProt Entry Name    GHSR_RAT
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 NCBI Summary for Ghsr    has G-protein coupled receptor binding activity to ligand ghrelin; plays a role in regulation of growth hormone release [RGD, Feb 2006]
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 UniProt Comments for Ghsr    GHSR: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA). Short stature is defined by a subnormal rate of growth. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Cellular Component: neuron projection; cell surface; cell; integral to membrane; plasma membrane; lipid raft

Molecular Function: growth hormone secretagogue receptor activity; G-protein coupled receptor activity; protein binding; growth hormone receptor binding; hormone binding; peptide hormone binding; growth hormone-releasing hormone receptor activity

Biological Process: response to food; positive regulation of insulin-like growth factor receptor signaling pathway; hormone-mediated signaling; response to hormone stimulus; adult feeding behavior; negative regulation of interleukin-6 biosynthetic process; positive regulation of multicellular organism growth; decidualization; negative regulation of interleukin-1 beta production; negative regulation of insulin secretion; growth hormone secretion; G-protein coupled receptor protein signaling pathway; positive regulation of fatty acid metabolic process; regulation of synaptogenesis; cellular response to insulin stimulus; actin polymerization and/or depolymerization; negative regulation of inflammatory response; positive regulation of appetite; regulation of hindgut contraction; negative regulation of tumor necrosis factor biosynthetic process
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 Research Articles on Ghsr    1. These data suggest that ghrelin receptor-deficient rats leads to an early onset decrement in hippocampal structural integrity that may manifest in non- spatial-related behavioral deficits.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Ghsr antibodyPathways associated with anti-Ghsr antibody
 Reference Product  PubMed Publications
 Ghrl antibody  >27 publications with Ghsr and Ghrl
 Npy antibody  >11 publications with Ghsr and Npy
 Ghrh antibody  >10 publications with Ghsr and Ghrh
 Agrp antibody  >6 publications with Ghsr and Agrp
 Ghrhr antibody  >4 publications with Ghsr and Ghrhr
 Sst antibody  >3 publications with Ghsr and Sst
 Gh1 antibody  >3 publications with Ghsr and Gh1
 Igf1 antibody  >3 publications with Ghsr and Igf1
 Lep antibody  >2 publications with Ghsr and Lep
 Mboat4 antibody  >1 publications with Ghsr and Mboat4
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
Diseases associated with anti-Ghsr antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >19 publications with Ghsr and Nervous System Diseases
 Weight Loss Antibodies  >17 publications with Ghsr and Weight Loss
 Inflammation Antibodies  >14 publications with Ghsr and Inflammation
 Death Antibodies  >10 publications with Ghsr and Death
 Musculoskeletal Diseases Antibodies  >10 publications with Ghsr and Musculoskeletal Diseases
 Bone Diseases Antibodies  >10 publications with Ghsr and Bone Diseases
 Carcinoma Antibodies  >9 publications with Ghsr and Carcinoma
 Hyperglycemia Antibodies  >8 publications with Ghsr and Hyperglycemia
 Heart Diseases Antibodies  >8 publications with Ghsr and Heart Diseases
 Necrosis Antibodies  >6 publications with Ghsr and Necrosis
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