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anti-GFAP antibody :: Rabbit Glial fibrillary acidic protein Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1489669
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glial fibrillary acidic protein (GFAP), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Glial fibrillary acidic protein polyclonal Antibody

 Product Gene Name   

anti-GFAP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    137780
 3D Structure    ModBase 3D Structure for P14136
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat. Other species are not tested. Please decide the specificity
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Glial fibrillary acidic protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6170 / sc-6171 / sc-9065
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-GFAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GFAP antibody

   GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
 Applications Tested/Suitable for anti-GFAP antibody   

ELISA (EIA), Western Blot (WB)

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 Western Blot (WB) of anti-GFAP antibody    Western Blot
Positive WB detected in:Mouse heart tissue,Mouse kidney tissue,Mouse brain tissue
All lanes: Gfap antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 50,51 kDa
Observed band size: 50 kDa

anti-GFAP antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-GFAP antibody    Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: GFAP antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 50,51 KDa
Observed band size: 50,51 KDa

anti-GFAP antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-GFAP antibody    Immunohistochemistry analysis of human brain tissue using MBS1489669 at dilution of 1:100
anti-GFAP antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-GFAP antibody    Immunohistochemistry analysis of human glioma cancer using MBS1489669 at dilution of 1:100
anti-GFAP antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-GFAP antibody    Immunofluorescent analysis of A549 cells using MBS1489669 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-GFAP antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for GFAP. It may not necessarily be applicable to this product.
 NCBI GI #    196115290
 NCBI GeneID    2670
 NCBI Accession #    NP_001124491.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001131019.2 [Other Products]
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 UniProt Primary Accession #    P14136 [Other Products]
 UniProt Secondary Accession #    Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0; B2RD44; D3DX59; E9PAX3 [Other Products]
 UniProt Related Accession #    P14136 [Other Products]
 Molecular Weight    49,508 Da
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 NCBI Official Full Name    glial fibrillary acidic protein isoform 2
 NCBI Official Synonym Full Names    glial fibrillary acidic protein
 NCBI Official Symbol    GFAP [Similar Products]
 NCBI Official Synonym Symbols   
ALXDRD
[Similar Products]
 NCBI Protein Information    glial fibrillary acidic protein
 UniProt Protein Name    Glial fibrillary acidic protein
 Protein Family    Glial fibrillary acidic protein
 UniProt Gene Name    GFAP [Similar Products]
 UniProt Synonym Gene Names    GFAP [Similar Products]
 UniProt Entry Name    GFAP_HUMAN
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 NCBI Summary for GFAP    This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
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 UniProt Comments for GFAP    GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cytoplasm; cytosol; intermediate filament; intermediate filament cytoskeleton; lysosome; membrane; myelin sheath

Molecular Function: integrin binding; kinase binding; protein binding; structural constituent of cytoskeleton

Biological Process: astrocyte development; Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; intermediate filament organization; neurite regeneration; regulation of neurotransmitter uptake; regulation of protein complex assembly; response to wounding

Disease: Alexander Disease
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 Research Articles on GFAP    1. It could be a clinically relevant marker associated with tumor invasiveness in cerebral astrocytomas.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GFAP antibodyPathways associated with anti-GFAP antibody
 Reference Product  PubMed Publications
 S100B antibody  >185 publications with GFAP and S100B
 SRC antibody  >26 publications with GFAP and SRC
 PSEN1 antibody  >14 publications with GFAP and PSEN1
 S100A1 antibody  >12 publications with GFAP and S100A1
 PRNP antibody  >11 publications with GFAP and PRNP
 RBFOX3 antibody  >3 publications with GFAP and RBFOX3
 PSEN2 antibody  >1 publications with GFAP and PSEN2
 CDK1 antibody  >1 publications with GFAP and CDK1
 NCOR1 antibody  >1 publications with GFAP and NCOR1
 Products by Pathway  Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Nuclear Signaling By ERBB4 Pathway antibodies  Nuclear Signaling By ERBB4 Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By ERBB4 Pathway antibodies  Signaling By ERBB4 Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
Diseases associated with anti-GFAP antibodyOrgans/Tissues associated with anti-GFAP antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5207 publications with GFAP and Nervous System Diseases
 Brain Diseases Antibodies  >3937 publications with GFAP and Brain Diseases
 Disease Models, Animal Antibodies  >1586 publications with GFAP and Disease Models, Animal
 Gliosis Antibodies  >1175 publications with GFAP and Gliosis
 Neurodegenerative Diseases Antibodies  >1048 publications with GFAP and Neurodegenerative Diseases
 Cardiovascular Diseases Antibodies  >948 publications with GFAP and Cardiovascular Diseases
 Brain Injuries Antibodies  >750 publications with GFAP and Brain Injuries
 Inflammation Antibodies  >748 publications with GFAP and Inflammation
 Necrosis Antibodies  >632 publications with GFAP and Necrosis
 Nerve Degeneration Antibodies  >556 publications with GFAP and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8355 publications with GFAP and Brain
 Nerve Antibodies  >3554 publications with GFAP and Nerve
 Blood Antibodies  >1706 publications with GFAP and Blood
 Spinal Cord Antibodies  >1484 publications with GFAP and Spinal Cord
 Eye Antibodies  >1050 publications with GFAP and Eye
 Muscle Antibodies  >548 publications with GFAP and Muscle
 Ganglia Antibodies  >312 publications with GFAP and Ganglia
 Bone Marrow Antibodies  >267 publications with GFAP and Bone Marrow
 Liver Antibodies  >217 publications with GFAP and Liver
 Connective Tissue Antibodies  >203 publications with GFAP and Connective Tissue
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