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anti-G6PD antibody :: Rabbit anti-Human Glucose 6 Phosphate Dehydrogenase (G6PD) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2001479 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $165 +1 FREE 8GB USB
0.1 mg  /  $210 +1 FREE 8GB USB
0.2 mg  /  $310 +1 FREE 8GB USB
1 mg  /  $725 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glucose 6 Phosphate Dehydrogenase (G6PD), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Glucose 6 Phosphate Dehydrogenase (G6PD)

 Product Gene Name   

anti-G6PD antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
Biotin Conjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2006183)
 Matching Pairs    Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
Antigen: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2009638)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
APC-CY7 Conjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2046514)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
PE Conjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2046515)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
APC-CY7 Conjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2046516)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
Cy3 Conjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2046517)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
FITC Conjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2046518)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
HRP Conjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2046519)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Glucose 6 Phosphate Dehydrogenase (G6PD) (MBS2001479)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF -MAEQVALSR T QVCGILREEL FQGDAFHQSD THIFIIMGAS GDLAKKKIYP TIWWLFRDGL LPENTFIVGY ARSRLTVADI RKQSEPFFKA TPEEKLKLED FFARNSYVAG QYDDAASYQR LNSHMNALHL GSQANRLFYL ALPPTVYEAV TKNIHESCMS QIGWNRIIVE KPFGRDLQSS DRLSNHISSL FREDQIYRID HYLGKEMVQN LMVLRFANRI FGPIWNRDNI ACVILTFKEP FGTEGRGGYF DEFGIIRDVM QNHLLQMLCL VAMEKPASTN SDDVRDEKVK VLKCISEVQA NNVVLGQYVG NPDGEGEATK GYLDDPTVPR GSTTATFAAV VLYVENERWD GVPFILRCGK ALNERKAEVR LQFHDVAGDI FHQQCKRNEL VIRVQPNEAV YTKMMTKKPG MFFNPEESEL DLTYGNRYKN VKLPDAYERL ILDVFCGSQM HFVRSDELRE AWRIFTPLLH QIELEKPKPI PYIYGSRGPT EADELMKRVG FQYEGTYKWV NPHKL
 OMIM    X03674 mRNA
 3D Structure    ModBase 3D Structure for P11413
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against G6PD. It has been selected for its ability to recognize G6PD in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant G6PD (Met1~Leu515) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2046516
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-G6PD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-G6PD antibody    Knock-Out Validation Antibody
 Applications Tested/Suitable for anti-G6PD antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-G6PD antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) Knockout Verification of anti-G6PD antibody    Knockout Verification: Lane 1: Wild-type Hela cell lysate; Lane 2: G6PD knockout Hela cell lysate; Predicted MW: 62kd Observed MW: 60kd Primary Ab: 1ug/ml Rabbit Anti-Human G6PD Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-G6PD antibody Western Blot (WB) Knockout Verification (WB) image
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 Western Blot (WB) of anti-G6PD antibody    Western Blot; Sample: Human Hela cell lysate; Primary Ab: 1ug/ml Rabbit Anti-Human G6PD Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-G6PD antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-G6PD antibody    Western Blot; Sample: Recombinant protein.
anti-G6PD antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-G6PD antibody    DAB staining on IHC-P. Samples: Human Tissue)
anti-G6PD antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for G6PD. It may not necessarily be applicable to this product.
 NCBI GI #    109389365
 NCBI GeneID    2539
 NCBI Accession #    NP_000393.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_000402.4 [Other Products]
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 UniProt Primary Accession #    P11413 [Other Products]
 UniProt Secondary Accession #    Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2; D3DWX9 [Other Products]
 UniProt Related Accession #    P11413 [Other Products]
 Molecular Weight    62,468 Da
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 NCBI Official Full Name    glucose-6-phosphate 1-dehydrogenase isoform a
 NCBI Official Synonym Full Names    glucose-6-phosphate dehydrogenase
 NCBI Official Symbol    G6PD [Similar Products]
 NCBI Official Synonym Symbols   
G6PD1
[Similar Products]
 NCBI Protein Information    glucose-6-phosphate 1-dehydrogenase
 UniProt Protein Name    Glucose-6-phosphate 1-dehydrogenase
 UniProt Gene Name    G6PD [Similar Products]
 UniProt Synonym Gene Names    G6PD [Similar Products]
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 NCBI Summary for G6PD    This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for G6PD    G6PD: glucose-6-phosphate dehydrogenase. A cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two splice variant isoforms have been described. The long isoform is found in lymphoblasts, granulocytes and sperm.

Protein type: Carbohydrate Metabolism - pentose phosphate pathway; Cell development/differentiation; EC 1.1.1.49; Other Amino Acids Metabolism - glutathione; Oxidoreductase

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; cytoplasmic side of plasma membrane; cytosol; extracellular exosome; membrane; nucleus

Molecular Function: glucose binding; glucose-6-phosphate dehydrogenase activity; identical protein binding; NADP binding; protein binding; protein homodimerization activity

Biological Process: cellular response to oxidative stress; cholesterol biosynthetic process; erythrocyte maturation; glucose 6-phosphate metabolic process; glucose metabolic process; glutathione metabolic process; lipid metabolic process; NADP metabolic process; NADPH regeneration; negative regulation of protein glutathionylation; negative regulation of reactive oxygen species metabolic process; pentose biosynthetic process; pentose-phosphate shunt; pentose-phosphate shunt, oxidative branch; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; regulation of neuron apoptosis; response to ethanol; response to food; response to iron(III) ion; response to organic cyclic compound; ribose phosphate biosynthetic process; substantia nigra development

Disease: Anemia, Nonspherocytic Hemolytic, Due To G6pd Deficiency; Favism, Susceptibility To; Malaria, Susceptibility To
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 Research Articles on G6PD    1. We concluded that the MeltPro G6PD assay is useful as a diagnostic or screening tool for G6PD deficiency in clinical settings
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-G6PD antibodyPathways associated with anti-G6PD antibody
 Reference Product  PubMed Publications
 GPI antibody  >59 publications with G6PD and GPI
 PGD antibody  >57 publications with G6PD and PGD
 TKT antibody  >8 publications with G6PD and TKT
 H6PD antibody  >4 publications with G6PD and H6PD
 INS antibody  >3 publications with G6PD and INS
 Products by Pathway  Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
Diseases associated with anti-G6PD antibodyOrgans/Tissues associated with anti-G6PD antibody
 Disease Name  Pubmed Publications
 Glucosephosphate Dehydrogenase Deficiency Antibodies  >5005 publications with G6PD and Glucosephosphate Dehydrogenase Deficiency
 Anemia Antibodies  >4761 publications with G6PD and Anemia
 Anemia, Hemolytic Antibodies  >4658 publications with G6PD and Anemia, Hemolytic
 Hemolysis Antibodies  >959 publications with G6PD and Hemolysis
 Poisoning Antibodies  >662 publications with G6PD and Poisoning
 Favism Antibodies  >594 publications with G6PD and Favism
 Nervous System Diseases Antibodies  >372 publications with G6PD and Nervous System Diseases
 Liver Diseases Antibodies  >242 publications with G6PD and Liver Diseases
 Anemia, Hemolytic, Congenital Nonspherocytic Antibodies  >214 publications with G6PD and Anemia, Hemolytic, Congenital Nonspherocytic
 Brain Diseases Antibodies  >197 publications with G6PD and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3606 publications with G6PD and Blood
 Liver Antibodies  >547 publications with G6PD and Liver
 Kidney Antibodies  >203 publications with G6PD and Kidney
 Muscle Antibodies  >144 publications with G6PD and Muscle
 Bone Antibodies  >142 publications with G6PD and Bone
 Brain Antibodies  >129 publications with G6PD and Brain
 Skin Antibodies  >115 publications with G6PD and Skin
 Bone Marrow Antibodies  >100 publications with G6PD and Bone Marrow
 Lung Antibodies  >85 publications with G6PD and Lung
 Vascular Antibodies  >74 publications with G6PD and Vascular
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