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anti-GSH antibody :: Rabbit anti-General Glutathione (GSH) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2013376 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Structural Formula
Unit / Price
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glutathione (GSH), Polyclonal Antibody

★Popular Item★
 Also Known As   

FITC-linked Antibody to Glutathione (GSH)

 Product Gene Name   

anti-GSH antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Glutathione (GSH) (MBS2005791)
FITC Conjugated Antibody: Glutathione (GSH) (MBS2013376)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000001.10 (110210644..110226619). Location: 1p13.3
 OMIM    138380
 3D Structure    ModBase 3D Structure for P28161
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    General
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 Specificity    The antibody is a rabbit polyclonal antibody raised against GSH. It has been selected for its ability to recognize GSH in immunohistochemical staining and western blotting.
 Purity/Purification    Affinity Chromatography.
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    GSH-OVA
 Conjugation    FITC
 Immunogen Information    Small Molecule, GSH conjugated to OVA.
 Chemical Formula    C10H17N3O6S
  Mol. Mass    307.3g/mol
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-GSH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-GSH antibody    FITC Antibody
 Applications Tested/Suitable for anti-GSH antibody   

Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), ELISA

 Application Notes for anti-GSH antibody    Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5000
Optimal working dilutions must be determined by end user.
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 Structural Formula of anti-GSH antibody    anti-GSH antibody Structural Formula image
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NCBI/Uniprot data below describe general gene information for GSH. It may not necessarily be applicable to this product.
 NCBI GI #    215277000
 NCBI GeneID    2946
 NCBI Accession #    NP_001135840.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001142368.1 [Other Products]
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 UniProt Primary Accession #    P28161 [Other Products]
 UniProt Secondary Accession #    Q2M318; Q5TZY5; Q8WWE1; B4DRY4; E9PEM9 [Other Products]
 UniProt Related Accession #    P28161 [Other Products]
 Molecular Weight    25,745 Da
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 NCBI Official Full Name    glutathione S-transferase Mu 2 isoform 2
 NCBI Official Synonym Full Names    glutathione S-transferase mu 2 (muscle)
 NCBI Official Symbol    GSTM2 [Similar Products]
 NCBI Official Synonym Symbols   
GST4; GSTM; GTHMUS; GSTM2-2
[Similar Products]
 NCBI Protein Information    glutathione S-transferase Mu 2; GST, muscle; GST class-mu 2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-aryltransferase M2; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; S-(hydroxyalkyl)glutathione lyase M2; glutathione S-transferase M2 (muscle)
 UniProt Protein Name    Glutathione S-transferase Mu 2
 UniProt Synonym Protein Names   
GST class-mu 2; GSTM2-2
 UniProt Gene Name    GSTM2 [Similar Products]
 UniProt Synonym Gene Names    GST4 [Similar Products]
 UniProt Entry Name    GSTM2_HUMAN
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 NCBI Summary for GSH    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GSH    GSTM2: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family.

Protein type: Transferase; Motility/polarity/chemotaxis; EC 2.5.1.18

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: sarcoplasmic reticulum; cytoplasm; cytosol

Molecular Function: enzyme binding; protein homodimerization activity; glutathione binding; glutathione transferase activity; receptor binding

Biological Process: regulation of skeletal muscle contraction via regulation of the release of sequestered calcium ion; glutathione metabolic process; nitrobenzene metabolic process; xenobiotic metabolic process; xenobiotic catabolic process
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 Research Articles on GSH    1. High expression of GSTM1 and GSTM4, along with increased endogenous reduced glutathione levels, help to maintain a more reduced state of cytochrome c which decreases apoptosis thus contributing to methotrexate resistance in human MCF7 breast cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GSH antibodyPathways associated with anti-GSH antibody
 Reference Product  PubMed Publications
 GSTM1 antibody  >33 publications with GSH and GSTM1
 GSTM3 antibody  >25 publications with GSH and GSTM3
 GSTA2 antibody  >10 publications with GSH and GSTA2
 GSTZ1 antibody  >4 publications with GSH and GSTZ1
 GPX1 antibody  >4 publications with GSH and GPX1
 GPX4 antibody  >1 publications with GSH and GPX4
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with anti-GSH antibodyOrgans/Tissues associated with anti-GSH antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >10 publications with GSH and Liver Diseases
 Liver Neoplasms Antibodies  >6 publications with GSH and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with GSH and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >4 publications with GSH and Breast Neoplasms
 Hypertension Antibodies  >4 publications with GSH and Hypertension
 Neoplasms, Experimental Antibodies  >4 publications with GSH and Neoplasms, Experimental
 Liver Neoplasms, Experimental Antibodies  >3 publications with GSH and Liver Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >3 publications with GSH and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >3 publications with GSH and Disease Models, Animal
 Precancerous Conditions Antibodies  >3 publications with GSH and Precancerous Conditions
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >24 publications with GSH and Liver
 Blood Antibodies  >14 publications with GSH and Blood
 Muscle Antibodies  >11 publications with GSH and Muscle
 Heart Antibodies  >10 publications with GSH and Heart
 Lung Antibodies  >9 publications with GSH and Lung
 Kidney Antibodies  >7 publications with GSH and Kidney
 Brain Antibodies  >6 publications with GSH and Brain
 Intestine Antibodies  >4 publications with GSH and Intestine
 Ovary Antibodies  >4 publications with GSH and Ovary
 Testis Antibodies  >4 publications with GSH and Testis
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