AAH53578.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,631 Da
NCBI Official Full Name
Glutathione S-transferase alpha 1
NCBI Official Synonym Full Names
glutathione S-transferase alpha 1
NCBI Official Synonym Symbols
GST2; GTH1; GSTA1-1; GST-epsilon [Similar Products]
NCBI Protein Information
glutathione S-transferase A1
UniProt Protein Name
Glutathione S-transferase A1
UniProt Synonym Protein Names
GST HA subunit 1; GST class-alpha member 1; GST-epsilon; GSTA1-1; GTH1
NCBI Summary for GSTa1
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
UniProt Comments for GSTa1
GSTA1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Alpha family.
Protein type: EC 2.5.1.18; Other Amino Acids Metabolism - glutathione; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 6p12.2
Cellular Component: cytosol
Molecular Function: glutathione peroxidase activity; glutathione transferase activity
Biological Process: epithelial cell differentiation; glutathione metabolic process; linoleic acid metabolic process; metabolic process
Research Articles on GSTa1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-GSTa1 antibody
Pathways associated with anti-GSTa1 antibody
Diseases associated with anti-GSTa1 antibody
Organs/Tissues associated with anti-GSTa1 antibody
|