A7Y2X0
[Other Products]
UniProt Related Accession #
NCBI Official Full Name
glycine transporter 2
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
NCBI Protein Information
sodium- and chloride-dependent glycine transporter 2; glyT-2; xGlyT2; solute carrier family 6 member 5
UniProt Protein Name
Sodium- and chloride-dependent glycine transporter 2
UniProt Synonym Protein Names
Solute carrier family 6 member 5
UniProt Synonym Gene Names
UniProt Entry Name
SC6A5_XENLA
UniProt Comments for slc6a5
Function: Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses
By similarity. UniProtKB Q9Y345
Subcellular location: Membrane; Multi-pass membrane protein
Potential.
Tissue specificity: First expressed in late neurula stages in the anterior spinal cord, where expression intensifies through the tailbud stages, and by hatching, expression is seen in the hindbrain. During late hatching stages, expression extends along most of the length of the spinal cord, mildly intensifies in the hindbrain, and appears in localized regions of the lateral forebrain and medial midbrain. By the swimming tadpole stage, weak expression appears in the anterior hindbrain, with stronger expression in the posterior, post-mitotic neurons. Ref.1
Sequence similarities: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A5 subfamily. [View classification]
Research Articles on slc6a5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-slc6a5 antibody
|