NP_001295119.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,000 Da
NCBI Official Full Name
glycophorin-A isoform 3
NCBI Official Synonym Full Names
glycophorin A (MNS blood group)
NCBI Official Synonym Symbols
MN; GPA; MNS; GPSAT; PAS-2; CD235a; GPErik; HGpMiV; HGpMiXI; HGpSta(C) [Similar Products]
NCBI Protein Information
glycophorin-A
UniProt Protein Name
Glycophorin-A
UniProt Synonym Protein Names
MN sialoglycoprotein; PAS-2; Sialoglycoprotein alpha; CD_antigen: CD235a
UniProt Synonym Gene Names
UniProt Entry Name
GLPA_HUMAN
NCBI Summary for GPA
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]
UniProt Comments for GPA
Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).
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Products associated with anti-GPA antibody
Pathways associated with anti-GPA antibody
Diseases associated with anti-GPA antibody
Organs/Tissues associated with anti-GPA antibody
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