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anti-IID antibody :: Rabbit anti-Human Group IID secretory phospholipase A2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1490533
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Group IID secretory phospholipase A2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Group IID secretory phospholipase A2 polyclonal Antibody

 Product Synonym Names    GIID sPLA2; sPLA2-IID; PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA; stroma-associated homolog
 Product Gene Name   

anti-IID antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605630
 3D Structure    ModBase 3D Structure for Q9UNK4
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Group IID secretory phospholipase A2 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104296
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-IID antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-IID antibody

   PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2-linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined.
 Applications Tested/Suitable for anti-IID antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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 Immunohistochemistry (IHC) of anti-IID antibody    Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1490533 at dilution 1:100
anti-IID antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IID antibody    Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS1490533 at dilution 1:100
anti-IID antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IID antibody    Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS1490533 at dilution 1:100
anti-IID antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for IID. It may not necessarily be applicable to this product.
 NCBI GI #    425854812
 NCBI GeneID    26279
 NCBI Accession #    NP_001258743.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001271814.1 [Other Products]
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 UniProt Primary Accession #    Q9UNK4 [Other Products]
 UniProt Secondary Accession #    Q9UK01; A8K2Z1; B1AEL9 [Other Products]
 UniProt Related Accession #    Q9UNK4 [Other Products]
 Molecular Weight    16,546 Da
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 NCBI Official Full Name    group IID secretory phospholipase A2 isoform 2
 NCBI Official Synonym Full Names    phospholipase A2 group IID
 NCBI Official Symbol    PLA2G2D [Similar Products]
 NCBI Official Synonym Symbols   
SPLASH; sPLA2S; PLA2IID; sPLA2-IID
[Similar Products]
 NCBI Protein Information    group IID secretory phospholipase A2
 UniProt Protein Name    Group IID secretory phospholipase A2
 UniProt Synonym Protein Names   
PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA, stroma-associated homolog
 Protein Family    Group IID secretory phospholipase
 UniProt Gene Name    PLA2G2D [Similar Products]
 UniProt Synonym Gene Names    SPLASH; GIID sPLA2; sPLA2-IID [Similar Products]
 UniProt Entry Name    PA2GD_HUMAN
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 NCBI Summary for IID    This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
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 UniProt Comments for IID    PLA2G2D: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined. Belongs to the phospholipase A2 family.

Protein type: Secreted, signal peptide; Phospholipase; EC 3.1.1.4; Lipid Metabolism - ether lipid; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - linoleic acid; Lipid Metabolism - arachidonic acid; Secreted

Chromosomal Location of Human Ortholog: 1p36.12

Cellular Component: extracellular region

Molecular Function: calcium ion binding; heparan sulfate proteoglycan binding; heparin binding; phospholipase A2 activity

Biological Process: CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; glycerophospholipid biosynthetic process; inflammatory response; lipid catabolic process; negative regulation of T cell proliferation; phosphatidic acid biosynthetic process; phospholipid metabolic process
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 Research Articles on IID    1. sPLA(2)-IID is present at the head and midpiece in the human sperm, and its activation seems to be involved in acrosomal exocytosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IID antibodyPathways associated with anti-IID antibody
 Reference Product  PubMed Publications
 PLA2G6 antibody  >3 publications with IID and PLA2G6
 PLA2G7 antibody  >2 publications with IID and PLA2G7
 PLA2G3 antibody  >2 publications with IID and PLA2G3
 PLA2G12B antibody  >1 publications with IID and PLA2G12B
 PLA2R1 antibody  >1 publications with IID and PLA2R1
 PLA2G12A antibody  >1 publications with IID and PLA2G12A
 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Acyl Chain Remodelling Of PE Pathway antibodies  Acyl Chain Remodelling Of PE Pathway Diagram
 Acyl Chain Remodelling Of PG Pathway antibodies  Acyl Chain Remodelling Of PG Pathway Diagram
 Acyl Chain Remodelling Of PI Pathway antibodies  Acyl Chain Remodelling Of PI Pathway Diagram
 Acyl Chain Remodelling Of PS Pathway antibodies  Acyl Chain Remodelling Of PS Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
Diseases associated with anti-IID antibodyOrgans/Tissues associated with anti-IID antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6 publications with IID and Inflammation
 Lung Diseases Antibodies  >4 publications with IID and Lung Diseases
 Adenocarcinoma Antibodies  >2 publications with IID and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >2 publications with IID and Cardiovascular Diseases
 Weight Loss Antibodies  >2 publications with IID and Weight Loss
 Necrosis Antibodies  >2 publications with IID and Necrosis
 Heart Diseases Antibodies  >1 publications with IID and Heart Diseases
 Liver Diseases Antibodies  >1 publications with IID and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with IID and Liver Neoplasms
 Fatty Liver Antibodies  >1 publications with IID and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with IID and Blood
 Lymph Node Antibodies  >2 publications with IID and Lymph Node
 Lung Antibodies  >2 publications with IID and Lung
 Kidney Antibodies  >2 publications with IID and Kidney
 Spleen Antibodies  >1 publications with IID and Spleen
 Intestine Antibodies  >1 publications with IID and Intestine
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