P07305
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW 19kDa/20kDa Observed MW 30kDa
NCBI Official Full Name
H1F0
NCBI Official Synonym Full Names
H1 histone family member 0
NCBI Official Synonym Symbols
NCBI Protein Information
histone H1.0
UniProt Protein Name
Histone H1.0
UniProt Synonym Protein Names
Histone H1'; Histone H1(0)
UniProt Synonym Gene Names
UniProt Entry Name
H10_HUMAN
NCBI Summary for H1F0
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
UniProt Comments for H1F0
H1F0: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division. Belongs to the histone H1/H5 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: actin cytoskeleton; Golgi apparatus; nuclear chromatin; nucleoplasm; nucleus
Molecular Function: chromatin DNA binding; protein binding
Biological Process: DNA fragmentation during apoptosis
Research Articles on H1F0
Precautions
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Disclaimer
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Products associated with anti-H1F0 antibody
Pathways associated with anti-H1F0 antibody
Diseases associated with anti-H1F0 antibody
Organs/Tissues associated with anti-H1F0 antibody
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