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anti-HAVCR1 antibody :: Rabbit anti-Human HAVCR1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7005998
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HAVCR1, Polyclonal Antibody

★Popular Item★
 Also Known As   

HAVCR1 Antibody

 Product Synonym Names    Hepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1; HAVCR1; KIM1; TIM1; TIMD1
 Product Gene Name   

anti-HAVCR1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606518
 3D Structure    ModBase 3D Structure for Q96D42
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Hepatitis A virus cellular receptor 1 protein(21-290AA)
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-HAVCR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HAVCR1 antibody

   May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.
 Applications Tested/Suitable for anti-HAVCR1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-HAVCR1 antibody    Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
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 Western Blot (WB) of anti-HAVCR1 antibody    Western blot
All lanes: HAVCR1 antibody at 2ug/ml+mouse brain tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 39kDa
Observed band size: 39kDa

anti-HAVCR1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-HAVCR1 antibody    Immunohistochemistry of paraffin-embedded human testis tissue using MBS7005998 at dilution 1:100
anti-HAVCR1 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-HAVCR1 antibody    Western Blot
Positive WB detected in: mouse liver,mouse brain,mouse thymus
All lanes: HAVCR1 antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 33 kDa
Observed band size: 39 kDa

anti-HAVCR1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for HAVCR1. It may not necessarily be applicable to this product.
 NCBI GI #    290560750
 NCBI GeneID    26762
 NCBI Accession #    NP_001166864.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001173393.2 [Other Products]
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 UniProt Primary Accession #    Q96D42 [Other Products]
 UniProt Secondary Accession #    O43656 [Other Products]
 UniProt Related Accession #    Q96D42 [Other Products]
 Molecular Weight    38,720 Da
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 NCBI Official Full Name    hepatitis A virus cellular receptor 1 isoform a
 NCBI Official Synonym Full Names    hepatitis A virus cellular receptor 1
 NCBI Official Symbol    HAVCR1 [Similar Products]
 NCBI Official Synonym Symbols   
TIM; KIM1; TIM1; CD365; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1
[Similar Products]
 NCBI Protein Information    hepatitis A virus cellular receptor 1
 UniProt Protein Name    Hepatitis A virus cellular receptor 1
 UniProt Synonym Protein Names   
Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1
 Protein Family    Hepatitis A virus cellular receptor
 UniProt Gene Name    HAVCR1 [Similar Products]
 UniProt Synonym Gene Names    KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1 [Similar Products]
 UniProt Entry Name    HAVR1_HUMAN
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 NCBI Summary for HAVCR1    The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. [provided by RefSeq, Apr 2015]
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 UniProt Comments for HAVCR1    TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: integral to membrane

Molecular Function: viral receptor activity

Biological Process: entry of virus into host cell

Disease: Ige Responsiveness, Atopic
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 Research Articles on HAVCR1    1. Following ICU admission, urinary levels of KIM-1 increase in patients with acute kidney injury.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HAVCR1 antibodyDiseases associated with anti-HAVCR1 antibody
 Reference Product  PubMed Publications
 LCN2 antibody  >154 publications with HAVCR1 and LCN2
 IL18 antibody  >84 publications with HAVCR1 and IL18
 FABP1 antibody  >26 publications with HAVCR1 and FABP1
 CST3 antibody  >19 publications with HAVCR1 and CST3
 PKD2 antibody  >3 publications with HAVCR1 and PKD2
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >271 publications with HAVCR1 and Kidney Diseases
 Acute Kidney Injury Antibodies  >220 publications with HAVCR1 and Acute Kidney Injury
 Renal Insufficiency Antibodies  >164 publications with HAVCR1 and Renal Insufficiency
 Proteinuria Antibodies  >64 publications with HAVCR1 and Proteinuria
 Inflammation Antibodies  >53 publications with HAVCR1 and Inflammation
 Cardiovascular Diseases Antibodies  >49 publications with HAVCR1 and Cardiovascular Diseases
 Lung Diseases Antibodies  >37 publications with HAVCR1 and Lung Diseases
 Necrosis Antibodies  >37 publications with HAVCR1 and Necrosis
 Disease Models, Animal Antibodies  >35 publications with HAVCR1 and Disease Models, Animal
 Liver Diseases Antibodies  >28 publications with HAVCR1 and Liver Diseases
Organs/Tissues associated with anti-HAVCR1 antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >321 publications with HAVCR1 and Kidney
 Brain Antibodies  >11 publications with HAVCR1 and Brain
 Intestine Antibodies  >7 publications with HAVCR1 and Intestine
 Mixed Antibodies  >2 publications with HAVCR1 and Mixed
 Eye Antibodies  >2 publications with HAVCR1 and Eye
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