NP_001311152.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform 2
NCBI Official Synonym Full Names
3-hydroxy-3-methylglutaryl-CoA synthase 1
NCBI Official Synonym Symbols
NCBI Protein Information
hydroxymethylglutaryl-CoA synthase, cytoplasmic
UniProt Protein Name
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
UniProt Synonym Protein Names
3-hydroxy-3-methylglutaryl coenzyme A synthase
UniProt Synonym Gene Names
UniProt Entry Name
HMCS1_HUMAN
UniProt Comments for HMGCS1
HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.
Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Transferase; EC 2.3.3.10; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - butanoate
Chromosomal Location of Human Ortholog: 5p14-p13
Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane
Molecular Function: drug binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; organic acid binding; protein homodimerization activity
Biological Process: brain development; cholesterol biosynthetic process; isoprenoid biosynthetic process; lipid metabolic process; liver development; male gonad development; response to drug; response to lipoprotein stimulus; response to low light intensity; response to purine; response to tellurium ion; response to vitamin E
Research Articles on HMGCS1
Precautions
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Pathways associated with anti-HMGCS1 antibody
Diseases associated with anti-HMGCS1 antibody
Organs/Tissues associated with anti-HMGCS1 antibody
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