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anti-HNRNPC antibody :: Rabbit HNRNPC Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2542995
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HNRNPC, Polyclonal Antibody

★Popular Item★
 Also Known As   

HNRNPC Polyclonal Antibody

 Product Synonym Names    C1; C2; HNRNP; HNRPC; SNRPC
 Product Gene Name   

anti-HNRNPC antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M29063 mRNA
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purification
 Concentration    2mg/ml (lot specific)
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 Immunogen    Synthetic peptide of human HNRNPC
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10041 / sc-10037 / sc-15386
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 Preparation and Storage    Store at -20 degree C. Avoid freeze/thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-HNRNPC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HNRNPC antibody

   This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. 
 Applications Tested/Suitable for anti-HNRNPC antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-HNRNPC antibody    ELISA: 1:1000-2000
WB: 1:200-1000
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 Western Blot (WB) of anti-HNRNPC antibody    Western Blot analysis of K562 cell using HNRNPC Polyclonal Antibody at dilution of 1/200
anti-HNRNPC antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for HNRNPC. It may not necessarily be applicable to this product.
 NCBI GI #    117190254
 NCBI GeneID    3183
 NCBI GenBank Nucleotide #    NM_001077443.1 [Other Products]
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 UniProt Secondary Accession #    P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; D3DS19; D3DS22 [Other Products]
 UniProt Related Accession #    P07910 [Other Products]
 Molecular Weight    34 kDa
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 NCBI Official Full Name    heterogeneous nuclear ribonucleoproteins C1/C2 isoform b
 NCBI Official Synonym Full Names    heterogeneous nuclear ribonucleoprotein C (C1/C2)
 NCBI Official Symbol    HNRNPC [Similar Products]
 NCBI Official Synonym Symbols   
C1; C2; HNRNP; HNRPC; SNRPC
[Similar Products]
 NCBI Protein Information    heterogeneous nuclear ribonucleoproteins C1/C2
 UniProt Protein Name    Heterogeneous nuclear ribonucleoproteins C1/C2
 Protein Family    Heterogeneous nuclear ribonucleoprotein
 UniProt Gene Name    HNRNPC [Similar Products]
 UniProt Synonym Gene Names    HNRPC; hnRNP C1/C2 [Similar Products]
 UniProt Entry Name    HNRPC_HUMAN
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 NCBI Summary for HNRNPC    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HNRNPC    hnRNP C1/C2: a heterogeneous nuclear ribonucleoprotein. May play a role in ribonucleosome assembly by neutralizing basic proteins such as A and B core hnRNP. Contains 1 RNA recognition motif (RRM) domain. Two alternatively spliced isoforms have been described.

Protein type: RNA splicing; RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytosol; membrane; nuclear chromatin; nucleoplasm; nucleus; protein complex; spliceosome; telomerase holoenzyme complex

Molecular Function: identical protein binding; mRNA 3'-UTR binding; nucleosomal DNA binding; poly(U) binding; protein binding

Biological Process: ATP-dependent chromatin remodeling; gene expression; negative regulation of telomere maintenance via telomerase; nuclear mRNA splicing, via spliceosome; osteoblast differentiation; protein sumoylation; RNA splicing
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 Research Articles on HNRNPC    1. These findings suggest that hnRNP C1/C2 is involved in dengue virus replication at the stage of viral RNA synthesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HNRNPC antibodyPathways associated with anti-HNRNPC antibody
 Reference Product  PubMed Publications
 HNRNPM antibody  >2 publications with HNRNPC and HNRNPM
 HNRNPD antibody  >1 publications with HNRNPC and HNRNPD
 HNRNPA1 antibody  >1 publications with HNRNPC and HNRNPA1
 DHX9 antibody  >1 publications with HNRNPC and DHX9
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Regulation Of Telomerase Pathway antibodies  Regulation Of Telomerase Pathway Diagram
 SUMO E3 Ligases SUMOylate Target Proteins Pathway antibodies  SUMO E3 Ligases SUMOylate Target Proteins Pathway Diagram
 SUMOylation Pathway antibodies  SUMOylation Pathway Diagram
 SUMOylation Of RNA Binding Proteins Pathway antibodies  SUMOylation Of RNA Binding Proteins Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
Diseases associated with anti-HNRNPC antibodyOrgans/Tissues associated with anti-HNRNPC antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with HNRNPC and Breast Neoplasms
 Lung Neoplasms Antibodies  >3 publications with HNRNPC and Lung Neoplasms
 Lung Diseases Antibodies  >3 publications with HNRNPC and Lung Diseases
 Adenocarcinoma Antibodies  >2 publications with HNRNPC and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >2 publications with HNRNPC and Carcinoma, Hepatocellular
 Inflammation Antibodies  >2 publications with HNRNPC and Inflammation
 Neurobehavioral Manifestations Antibodies  >1 publications with HNRNPC and Neurobehavioral Manifestations
 Cardiovascular Diseases Antibodies  >1 publications with HNRNPC and Cardiovascular Diseases
 Hemorrhage Antibodies  >1 publications with HNRNPC and Hemorrhage
 Acute Kidney Injury Antibodies  >1 publications with HNRNPC and Acute Kidney Injury
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >8 publications with HNRNPC and Lung
 Liver Antibodies  >7 publications with HNRNPC and Liver
 Brain Antibodies  >4 publications with HNRNPC and Brain
 Ovary Antibodies  >2 publications with HNRNPC and Ovary
 Kidney Antibodies  >2 publications with HNRNPC and Kidney
 Embryonic Tissue Antibodies  >2 publications with HNRNPC and Embryonic Tissue
 Nerve Antibodies  >2 publications with HNRNPC and Nerve
 Testis Antibodies  >2 publications with HNRNPC and Testis
 Lymph Antibodies  >1 publications with HNRNPC and Lymph
 Blood Antibodies  >1 publications with HNRNPC and Blood
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