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anti-HS2ST1 antibody :: Rabbit anti-Human, Mouse HS2ST1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1491783
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HS2ST1, Polyclonal Antibody

★Popular Item★
 Also Known As   

HS2ST1 Antibody

 Product Synonym Names    Heparan sulfate 2-O-sulfotransferase 1 (EC:2.8.2.-); 2-O-sulfotransferase; 2OST; HS2ST1; HS2ST; KIAA0448
 Product Gene Name   

anti-HS2ST1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604844
 3D Structure    ModBase 3D Structure for Q7LGA3
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Heparan sulfate 2-O-sulfotransferase 1 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-103549 / sc-130779 / sc-292203
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-HS2ST1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HS2ST1 antibody

   Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity).
 Applications Tested/Suitable for anti-HS2ST1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-HS2ST1 antibody    Recommended dilution: WB:1:500-2000
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 Western Blot (WB) of anti-HS2ST1 antibody    Western blot
All lanes: HS2ST1 antibody at 6ug/ml
Lane 1:mouse skeletal muscle tissue
Lane 2:mouse heart tissue
Lane 3:PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 42,35,27 kDa
Observed band size: 42 kDa

anti-HS2ST1 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-HS2ST1 antibody    Western Blot
Positive WB detected in: Rat spleen tissue
All lanes: HS2ST1 antibody at 2.7ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 42,35,27 KDa
Observed band size: 42 KDa

anti-HS2ST1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-HS2ST1 antibody    Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS1491783 at dilution of 1:100
anti-HS2ST1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-HS2ST1 antibody    Immunohistochemistry of paraffin-embedded human lung cancer using MBS1491783 at dilution of 1:100
anti-HS2ST1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for HS2ST1. It may not necessarily be applicable to this product.
 NCBI GI #    197382758
 NCBI GeneID    9653
 NCBI Accession #    NP_001127964.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001134492.1 [Other Products]
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 UniProt Primary Accession #    Q7LGA3 [Other Products]
 UniProt Secondary Accession #    O75036; Q32NB5; Q8TAC5; Q9H441; Q9NUJ9; D3DT22 [Other Products]
 UniProt Related Accession #    Q7LGA3 [Other Products]
 Molecular Weight    26,757 Da
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 NCBI Official Full Name    heparan sulfate 2-O-sulfotransferase 1 isoform 2
 NCBI Official Synonym Full Names    heparan sulfate 2-O-sulfotransferase 1
 NCBI Official Symbol    HS2ST1 [Similar Products]
 NCBI Official Synonym Symbols   
dJ604K5.2
[Similar Products]
 NCBI Protein Information    heparan sulfate 2-O-sulfotransferase 1
 UniProt Protein Name    Heparan sulfate 2-O-sulfotransferase 1
 Protein Family    Heparan sulfate 2-O-sulfotransferase
 UniProt Gene Name    HS2ST1 [Similar Products]
 UniProt Synonym Gene Names    HS2ST; KIAA0448; 2-O-sulfotransferase; 2OST [Similar Products]
 UniProt Entry Name    HS2ST_HUMAN
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 NCBI Summary for HS2ST1    Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]
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 UniProt Comments for HS2ST1    HS2ST1: Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high- affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues. Belongs to the sulfotransferase 3 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Glycan Metabolism - heparan sulfate biosynthesis; Transferase; EC 2.8.2.-; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p22.3

Cellular Component: Golgi membrane; integral to membrane; membrane

Molecular Function: sulfotransferase activity

Biological Process: carbohydrate metabolic process; glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process
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 Research Articles on HS2ST1    1. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HS2ST1 antibodyPathways associated with anti-HS2ST1 antibody
 Reference Product  PubMed Publications
 GLCE antibody  >2 publications with HS2ST1 and GLCE
 NDST1 antibody  >1 publications with HS2ST1 and NDST1
 HS6ST1 antibody  >1 publications with HS2ST1 and HS6ST1
 Products by Pathway  Pathway Diagram
 Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway antibodies  Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway Diagram
 Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway antibodies  Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 HS-GAG Biosynthesis Pathway antibodies  HS-GAG Biosynthesis Pathway Diagram
 Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway antibodies  Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Metapathway Biotransformation antibodies  Metapathway Biotransformation Diagram
Diseases associated with anti-HS2ST1 antibodyOrgans/Tissues associated with anti-HS2ST1 antibody
 Disease Name  Pubmed Publications
 Lymphoma Antibodies  >1 publications with HS2ST1 and Lymphoma
 Mammary Neoplasms, Animal Antibodies  >1 publications with HS2ST1 and Mammary Neoplasms, Animal
 Neoplasms, Experimental Antibodies  >1 publications with HS2ST1 and Neoplasms, Experimental
 Fibrosis Antibodies  >1 publications with HS2ST1 and Fibrosis
 Neoplasm Metastasis Antibodies  >1 publications with HS2ST1 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >1 publications with HS2ST1 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with HS2ST1 and Bone
 Blood Antibodies  >1 publications with HS2ST1 and Blood
 Eye Antibodies  >1 publications with HS2ST1 and Eye
 Mammary Gland Antibodies  >1 publications with HS2ST1 and Mammary Gland
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