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anti-HSD17B13 antibody :: Rabbit anti-Human HSD17B13 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9401116
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HSD17B13, Polyclonal Antibody

★Popular Item★
 Also Known As   

HSD17B13 Antibody

 Product Synonym Names    SCDR9; NIIL497; SDR16C3; HMFN0376
 Product Gene Name   

anti-HSD17B13 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612127
 3D Structure    ModBase 3D Structure for Q7Z5P4
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody detects endogenous levels of total HSD17B13 protein.
 Purity/Purification    Antigen affinity purification.
 Form/Format    Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
 Concentration    1.3 mg/ml (lot specific)
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 Immunogen Type    Recombinant Protein
 Immunogen Description    Fusion protein corresponding to a region derived from internal residues of human hydroxysteroid (17-beta) dehydrogenase 13
 Target Name    HSD17B13
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 Preparation and Storage    Store at -20 degree C
 Other Notes    Small volumes of anti-HSD17B13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-HSD17B13 antibody

   17b-HSD13 (17b hydroxysteroid dehydrogenase type 13), also designated Short-chain dehydrogenase/reductase 9 (SCDR9), belongs to the 17b-HSD family of proteins, which regulate the availability of steroids within various tissues throughout the body. 17b-HSD13 is a 300 amino acid secreted protein that is highly expressed in liver and is also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. The gene encoding 17b-HSD13 maps to chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
 Product Categories/Family for anti-HSD17B13 antibody    Total protein Ab
 Applications Tested/Suitable for anti-HSD17B13 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-HSD17B13 antibody    Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
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 Testing Data of anti-HSD17B13 antibody    Gel: 10%SDS-PAGE
Lysates (from left to right): Human fetal liver tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/350 dilution
Secondary antibody dilution: 1/8000
Exposure time: 3 minutes
anti-HSD17B13 antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-HSD17B13 antibody    Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.
anti-HSD17B13 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for HSD17B13. It may not necessarily be applicable to this product.
 NCBI GI #    210032112
 NCBI GeneID    345275
 NCBI Accession #    BC112303 [Other Products]
 NCBI GenBank Nucleotide #    NM_001136230.2 [Other Products]
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 UniProt Primary Accession #    Q7Z5P4 [Other Products]
 UniProt Secondary Accession #    Q2M1L5; Q86W22; Q86W23; A8K9R9 [Other Products]
 UniProt Related Accession #    Q7Z5P4 [Other Products]
 Molecular Weight    34kd
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 NCBI Official Full Name    17-beta-hydroxysteroid dehydrogenase 13 isoform B
 NCBI Official Synonym Full Names    hydroxysteroid (17-beta) dehydrogenase 13
 NCBI Official Symbol    HSD17B13 [Similar Products]
 NCBI Official Synonym Symbols   
SCDR9; NIIL497; SDR16C3; HMFN0376
[Similar Products]
 NCBI Protein Information    17-beta-hydroxysteroid dehydrogenase 13
 UniProt Protein Name    17-beta-hydroxysteroid dehydrogenase 13
 UniProt Synonym Protein Names   
Short chain dehydrogenase/reductase family 16C member 3; Short-chain dehydrogenase/reductase 9
 Protein Family    17-beta-hydroxysteroid dehydrogenase
 UniProt Gene Name    HSD17B13 [Similar Products]
 UniProt Synonym Gene Names    SCDR9; SDR16C3; 17-beta-HSD 13 [Similar Products]
 UniProt Entry Name    DHB13_HUMAN
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 UniProt Comments for HSD17B13    HSD17B13: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.1.-.-; Secreted; Secreted, signal peptide; Oxidoreductase

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: extracellular region; lipid particle

Molecular Function: oxidoreductase activity

Biological Process: positive regulation of lipid biosynthetic process
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 Research Articles on HSD17B13    1. 17beta-HSD13 as a pathogenic protein in the development of nonalcoholic fatty liver disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HSD17B13 antibodyDiseases associated with anti-HSD17B13 antibody
 Reference Product  PubMed Publications
 HSD17B4 antibody  >1 publications with HSD17B13 and HSD17B4
 Disease Name  Pubmed Publications
 Diabetes Mellitus, Type 2 Antibodies  >1 publications with HSD17B13 and Diabetes Mellitus, Type 2
 Carcinoma, Hepatocellular Antibodies  >1 publications with HSD17B13 and Carcinoma, Hepatocellular
 Fatty Liver Antibodies  >1 publications with HSD17B13 and Fatty Liver
Organs/Tissues associated with anti-HSD17B13 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with HSD17B13 and Liver
 Blood Antibodies  >1 publications with HSD17B13 and Blood
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