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anti-HSP90AA1 antibody :: Rabbit HSP90AA1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2524344
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HSP90AA1, Polyclonal Antibody

★Popular Item★
 Also Known As   

HSP90AA1 Polyclonal Antibody

 Product Synonym Names    EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4
 Product Gene Name   

anti-HSP90AA1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    140571
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    2.9mg/mL (lot specific)
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 Immunogen    Recombinant protein of human HSP90AA1
 Calculated Molecular Weight: 85kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-HSP90AA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HSP90AA1 antibody

   The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene
 Product Categories/Family for anti-HSP90AA1 antibody    Cancer; Epigenetics
 Applications Tested/Suitable for anti-HSP90AA1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-HSP90AA1 antibody    WB: 1:500-1:2000
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 Western Blot (WB) of anti-HSP90AA1 antibody    Western Blot analysis of A549 and 293T cell, Mouse brain tissue, K562 and Hela cell using HSP90AA1 Polyclonal Antibody at dilution of 1:350
anti-HSP90AA1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for HSP90AA1. It may not necessarily be applicable to this product.
 NCBI GI #    154146191
 NCBI GeneID    3320
 NCBI Accession #    NP_005339.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005348.3 [Other Products]
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 UniProt Secondary Accession #    Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5; A8K500; B3KPJ9 [Other Products]
 UniProt Related Accession #    P07900 [Other Products]
 Molecular Weight    98,161 Da
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 NCBI Official Full Name    heat shock protein HSP 90-alpha isoform 2
 NCBI Official Synonym Full Names    heat shock protein 90kDa alpha (cytosolic), class A member 1
 NCBI Official Symbol    HSP90AA1 [Similar Products]
 NCBI Official Synonym Symbols   
EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4
[Similar Products]
 NCBI Protein Information    heat shock protein HSP 90-alpha; HSP 86; LPS-associated protein 2; epididymis luminal secretory protein 52; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; lipopolysaccharide-associated protein 2; renal carcinoma antigen NY-REN-38
 UniProt Protein Name    Heat shock protein HSP 90-alpha
 UniProt Synonym Protein Names   
Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38
 Protein Family    Heat shock protein
 UniProt Gene Name    HSP90AA1 [Similar Products]
 UniProt Synonym Gene Names    HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2 [Similar Products]
 UniProt Entry Name    HS90A_HUMAN
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 NCBI Summary for HSP90AA1    The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
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 UniProt Comments for HSP90AA1    HSP90A: a molecular chaperone of the heat shock protein 90 family. Has ATPase activity. Known to interact with a wide variety of proteins including steroid hormone receptors, neuropeptide Y, FKBP51/54, and FKBP52. G protein-coupled receptor kinases are stabilized by interacting with HSP 90. Hsp70 and Hsp90 promote tau solubility and tau binding to microtubules, reducing insoluble tau phosphorylation of tau.

Protein type: Chaperone; Heat shock protein

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: nucleoplasm; membrane; mitochondrion; cytoplasm; extracellular region; melanosome; plasma membrane; cytosol; nucleus

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; TPR domain binding; unfolded protein binding; nitric-oxide synthase regulator activity; ATPase activity; nucleotide binding; ATP binding

Biological Process: axon guidance; receptor-mediated endocytosis; positive regulation of nitric oxide biosynthetic process; organelle organization and biogenesis; signal transduction; protein import into mitochondrial outer membrane; nitric oxide metabolic process; response to unfolded protein; mitochondrial transport; innate immune response; protein refolding; mitotic cell cycle; regulation of nitric-oxide synthase activity; G2/M transition of mitotic cell cycle; chaperone-mediated protein complex assembly; vascular endothelial growth factor receptor signaling pathway
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 Research Articles on HSP90AA1    1. Data indicate that heat shock protein 90 (HSP90) expression was significantly higher in cyclin-dependent kinase inhibitor p16 (p16)-negative compared with p16-positive samples.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HSP90AA1 antibodyPathways associated with anti-HSP90AA1 antibody
 Reference Product  PubMed Publications
 AKT1 antibody  >3 publications with HSP90AA1 and AKT1
 HIF1A antibody  >3 publications with HSP90AA1 and HIF1A
 PTGES3 antibody  >3 publications with HSP90AA1 and PTGES3
 STIP1 antibody  >2 publications with HSP90AA1 and STIP1
 NR3C1 antibody  >1 publications with HSP90AA1 and NR3C1
 CDC37 antibody  >1 publications with HSP90AA1 and CDC37
 Products by Pathway  Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies  Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Attenuation Phase Pathway antibodies  Attenuation Phase Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
Diseases associated with anti-HSP90AA1 antibodyOrgans/Tissues associated with anti-HSP90AA1 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with HSP90AA1 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >4 publications with HSP90AA1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >3 publications with HSP90AA1 and Liver Diseases
 Immune System Diseases Antibodies  >3 publications with HSP90AA1 and Immune System Diseases
 Lung Neoplasms Antibodies  >3 publications with HSP90AA1 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with HSP90AA1 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >3 publications with HSP90AA1 and Breast Neoplasms
 Infertility, Male Antibodies  >2 publications with HSP90AA1 and Infertility, Male
 Liver Neoplasms Antibodies  >2 publications with HSP90AA1 and Liver Neoplasms
 Necrosis Antibodies  >2 publications with HSP90AA1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with HSP90AA1 and Blood
 Brain Antibodies  >7 publications with HSP90AA1 and Brain
 Lung Antibodies  >6 publications with HSP90AA1 and Lung
 Testis Antibodies  >6 publications with HSP90AA1 and Testis
 Liver Antibodies  >5 publications with HSP90AA1 and Liver
 Muscle Antibodies  >4 publications with HSP90AA1 and Muscle
 Embryonic Tissue Antibodies  >3 publications with HSP90AA1 and Embryonic Tissue
 Vascular Antibodies  >3 publications with HSP90AA1 and Vascular
 Stomach Antibodies  >3 publications with HSP90AA1 and Stomach
 Kidney Antibodies  >2 publications with HSP90AA1 and Kidney
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