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anti-HSP90beta antibody :: Rabbit HSP90beta Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2539237
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HSP90beta, Polyclonal Antibody

★Popular Item★
 Also Known As   

HSP90beta Polyclonal Antibody

 Product Synonym Names    HSP90AB1; HSP90B; HSPC2; HSPCB; Heat shock protein HSP 90-beta; HSP 90; Heat shock 84 kDa; HSP 84; HSP84
 Product Gene Name   

anti-HSP90beta antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    140572
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Monkey
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from human HSP90beta around the non-phosphorylation site of S254.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-HSP90beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-HSP90beta antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-HSP90beta antibody    WB: 1:500-1:2000, IHC: 1:50-1:200, IP: 1:100, IF: 1:50-1:100, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-HSP90beta antibody    Western Blot analysis of various cells using HSP90? Polyclonal Antibody at dilution of 1:2000.
anti-HSP90beta antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for HSP90beta. It may not necessarily be applicable to this product.
 NCBI GI #    431822408
 NCBI GeneID    3326
 NCBI Accession #    NP_001258901.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001271972.1 [Other Products]
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 UniProt Secondary Accession #    Q5T9W7; Q9NQW0; Q9NTK6; B2R5P0 [Other Products]
 UniProt Related Accession #    P08238 [Other Products]
 Molecular Weight    Calculated MW: 83
Observed MW: 90
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 NCBI Official Full Name    heat shock protein HSP 90-beta isoform c
 NCBI Official Synonym Full Names    heat shock protein 90kDa alpha family class B member 1
 NCBI Official Symbol    HSP90AB1 [Similar Products]
 NCBI Official Synonym Symbols   
HSP84; HSPC2; HSPCB; D6S182; HSP90B
[Similar Products]
 NCBI Protein Information    heat shock protein HSP 90-beta
 UniProt Protein Name    Heat shock protein HSP 90-beta
 UniProt Synonym Protein Names   
Heat shock 84 kDa; HSP 84; HSP84
 UniProt Gene Name    HSP90AB1 [Similar Products]
 UniProt Synonym Gene Names    HSP90B; HSPC2; HSPCB; HSP 90; HSP 84; HSP84 [Similar Products]
 UniProt Entry Name    HS90B_HUMAN
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 NCBI Summary for HSP90beta    This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]
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 UniProt Comments for HSP90beta    HSP90B: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Homodimer. Interacts with p53/TP53. Forms a complex with CDK6 and Hsp90/HSP90AB1. Interacts with UNC45A. Binding to UNC45A involves 2 UNC45A monomers per HSP90AB1 dimer. Interacts with CHORDC1 and DNAJC7. Interacts with FKBP4. Belongs to the heat shock protein 90 family.

Protein type: Heat shock protein; Chaperone

Chromosomal Location of Human Ortholog: 6p12

Cellular Component: apical plasma membrane; basolateral plasma membrane; brush border membrane; cell surface; cytoplasm; cytosol; inclusion body; melanosome; membrane; mitochondrion; nucleoplasm; signalosome

Molecular Function: ATP binding; dATP binding; double-stranded RNA binding; GTP binding; histone deacetylase binding; kinase binding; nitric-oxide synthase regulator activity; protein binding; protein kinase binding; sulfonylurea receptor binding; TPR domain binding; unfolded protein binding

Biological Process: axon guidance; innate immune response; negative regulation of neuron apoptosis; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; placenta development; positive regulation of cell size; positive regulation of nitric oxide biosynthetic process; positive regulation of protein binding; positive regulation of protein import into nucleus, translocation; protein folding; regulation of protein ubiquitination; response to salt stress; response to unfolded protein; virion attachment to host cell surface receptor
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 Research Articles on HSP90beta    1. These results suggest a means by which the hsp90beta interaction could prevent apo-sGCbeta1 from associating with its partner sGCalpha1 subunit while enabling structural changes to assist heme insertion into the H-NOX domain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HSP90beta antibodyPathways associated with anti-HSP90beta antibody
 Reference Product  PubMed Publications
 HSP90AA1 antibody  >15 publications with HSP90beta and HSP90AA1
 CDC37 antibody  >3 publications with HSP90beta and CDC37
 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Attenuation Phase Pathway antibodies  Attenuation Phase Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
Diseases associated with anti-HSP90beta antibodyOrgans/Tissues associated with anti-HSP90beta antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with HSP90beta and Nervous System Diseases
 Inflammation Antibodies  >6 publications with HSP90beta and Inflammation
 Lung Neoplasms Antibodies  >5 publications with HSP90beta and Lung Neoplasms
 Necrosis Antibodies  >4 publications with HSP90beta and Necrosis
 Breast Neoplasms Antibodies  >4 publications with HSP90beta and Breast Neoplasms
 Infertility, Male Antibodies  >3 publications with HSP90beta and Infertility, Male
 Liver Neoplasms Antibodies  >3 publications with HSP90beta and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with HSP90beta and Liver Diseases
 Disease Models, Animal Antibodies  >3 publications with HSP90beta and Disease Models, Animal
 Carcinoma, Hepatocellular Antibodies  >2 publications with HSP90beta and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with HSP90beta and Blood
 Lung Antibodies  >12 publications with HSP90beta and Lung
 Brain Antibodies  >8 publications with HSP90beta and Brain
 Intestine Antibodies  >5 publications with HSP90beta and Intestine
 Vascular Antibodies  >5 publications with HSP90beta and Vascular
 Ovary Antibodies  >5 publications with HSP90beta and Ovary
 Liver Antibodies  >4 publications with HSP90beta and Liver
 Embryonic Tissue Antibodies  >4 publications with HSP90beta and Embryonic Tissue
 Testis Antibodies  >4 publications with HSP90beta and Testis
 Kidney Antibodies  >4 publications with HSP90beta and Kidney
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