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anti-HPX antibody :: Rabbit anti-Rat Hemopexin (HPX) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2005235 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $185 +1 FREE 8GB USB
0.1 mg  /  $230 +1 FREE 8GB USB
0.2 mg  /  $350 +1 FREE 8GB USB
1 mg  /  $830 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hemopexin (HPX), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Hemopexin (HPX)

 Product Gene Name   

anti-HPX antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P20059
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Rat
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 Specificity    The antibody is a rabbit polyclonal antibody raised against HPX. It has been selected for its ability to recognize HPX in immunohistochemical staining andwestern blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant HPX (Glu31~Thr242) expressed in E.coli
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2061588
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-HPX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-HPX antibody   


 Application Notes for anti-HPX antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml

Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-HPX antibody    (Figure. Western Blot; Sample: Lane1: Rat Liver Tissue; Lane2: Rat Lung Tissue; Lane3: Rat Placenta Tissue; Lane4: Rat Serum.)
anti-HPX antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-HPX antibody    (Figure. Western Blot; Sample: Recombinant HPX, Rat.)
anti-HPX antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-HPX antibody    (Figure.DAB staining on IHC-P. Samples: Rat Tissue)
anti-HPX antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for HPX. It may not necessarily be applicable to this product.
 NCBI GI #    16758014
 NCBI GeneID    58917
 NCBI Accession #    NP_445770.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_053318.1 [Other Products]
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 UniProt Primary Accession #    P20059 [Other Products]
 UniProt Secondary Accession #    Q5BKB4 [Other Products]
 UniProt Related Accession #    P20059 [Other Products]
 Molecular Weight    51,351 Da
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 NCBI Official Full Name    hemopexin
 NCBI Official Synonym Full Names    hemopexin
 NCBI Official Symbol    Hpx [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    hemopexin
 UniProt Protein Name    Hemopexin
 Protein Family    Hemopexin
 UniProt Gene Name    Hpx [Similar Products]
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 NCBI Summary for HPX    a heme binding globulin protein [RGD, Feb 2006]
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 UniProt Comments for HPX    HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: cell; extracellular space

Molecular Function: heme transporter activity; metal ion binding

Biological Process: cellular iron ion homeostasis; heme metabolic process; heme transport; hemoglobin metabolic process; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of immunoglobulin production; positive regulation of tyrosine phosphorylation of STAT protein; regulation of protein metabolic process
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 Research Articles on HPX    1. Data suggest that apo-hemopexin isolated from plasma exchibits low endogenous levels of tyrosine nitration in the peptide YYCFQGNQFLR in the heme-binding site of human hemopexin, which was similarly nitrated in rabbit and rat hemopexins; heme binding by hemopexin declined as tyrosine nitration proceeded in vitro.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HPX antibodyPathways associated with anti-HPX antibody
 Reference Product  PubMed Publications
 Alb antibody  >4 publications with HPX and Alb
 Fga antibody  >1 publications with HPX and Fga
 Lrp1 antibody  >1 publications with HPX and Lrp1
 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram
Diseases associated with anti-HPX antibodyOrgans/Tissues associated with anti-HPX antibody
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >33 publications with HPX and Disease Models, Animal
 Inflammation Antibodies  >24 publications with HPX and Inflammation
 Liver Diseases Antibodies  >18 publications with HPX and Liver Diseases
 Cardiovascular Diseases Antibodies  >9 publications with HPX and Cardiovascular Diseases
 Liver Neoplasms Antibodies  >8 publications with HPX and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >8 publications with HPX and Carcinoma, Hepatocellular
 Immune System Diseases Antibodies  >7 publications with HPX and Immune System Diseases
 Death Antibodies  >6 publications with HPX and Death
 Kidney Diseases Antibodies  >5 publications with HPX and Kidney Diseases
 Fibrosis Antibodies  >4 publications with HPX and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >65 publications with HPX and Liver
 Pituitary Gland Antibodies  >11 publications with HPX and Pituitary Gland
 Ovary Antibodies  >9 publications with HPX and Ovary
 Testis Antibodies  >7 publications with HPX and Testis
 Pancreas Antibodies  >7 publications with HPX and Pancreas
 Spleen Antibodies  >6 publications with HPX and Spleen
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