NP_001191073.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
histone deacetylase 9 isoform 6
NCBI Official Synonym Full Names
histone deacetylase 9
NCBI Official Synonym Symbols
HD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL [Similar Products]
NCBI Protein Information
histone deacetylase 9
UniProt Protein Name
Histone deacetylase 9
UniProt Synonym Protein Names
Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; MEF2-interacting transcription repressor MITR
UniProt Synonym Gene Names
NCBI Summary for HDAC9
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for HDAC9
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.
Research Articles on HDAC9
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Products associated with anti-HDAC9 antibody
Pathways associated with anti-HDAC9 antibody
Diseases associated with anti-HDAC9 antibody
Organs/Tissues associated with anti-HDAC9 antibody
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