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anti-CCL1 antibody :: Rabbit anti-Human I-309 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS175764
Testing Data
Unit / Price
0.1 mg  /  $245 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

I-309 (CCL1), Polyclonal Antibody

 Also Known As   

Anti-I-309 antibody

 Product Synonym Names    C-C motif chemokine 1; chemokine(C-C motif) ligand 1; C-C motif chemokine 1 antibody; CCL1 antibody; CCL1_HUMAN antibody; Chemokine CC Motif Ligand 1 antibody; inflammatory cytokine I-309 antibody; P500 antibody; SCYA1 antibody; SISe antibody; small inducible cytokine A1 antibody; Small-inducible cytokine A1 antibody; T lymphocyte secreted protein I-309 antibody; T lymphocyte-secreted protein I-309 antibody; TCA3 antibody
 Product Gene Name   

anti-CCL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    182281
 3D Structure    ModBase 3D Structure for P22362
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    A synthetic peptide corresponding to a sequence at the C-terminus of human I-309 (80-96aa WVQRHRKMLRHCPSKRK).
 Contents    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CCL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CCL1 antibody

   Description: Rabbit IgG polyclonal antibody for C-C motif chemokine 1(CCL1) detection. Tested with WB in Human.
Background: CCL1, Chemokine(C-C motif) ligand 1, is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.
 Applications Tested/Suitable for anti-CCL1 antibody   

Western Blot (WB)

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 Testing Data of anti-CCL1 antibody    anti-CCL1 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CCL1. It may not necessarily be applicable to this product.
 NCBI GI #    123950
 NCBI GeneID    6346
 NCBI Accession #    P22362.1 [Other Products]
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 UniProt Primary Accession #    P22362 [Other Products]
 UniProt Secondary Accession #    Q2M309; B2R5G9 [Other Products]
 UniProt Related Accession #    P22362 [Other Products]
 Molecular Weight    10,992 Da
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 NCBI Official Full Name    C-C motif chemokine 1
 NCBI Official Synonym Full Names    chemokine (C-C motif) ligand 1
 NCBI Official Symbol    CCL1 [Similar Products]
 NCBI Official Synonym Symbols   
P500; SISe; TCA3; I-309; SCYA1
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 1; inflammatory cytokine I-309; T lymphocyte-secreted protein I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
 UniProt Protein Name    C-C motif chemokine 1
 UniProt Synonym Protein Names   
Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
 Protein Family    Cyclin
 UniProt Gene Name    CCL1 [Similar Products]
 UniProt Synonym Gene Names    SCYA1 [Similar Products]
 UniProt Entry Name    CCL1_HUMAN
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 NCBI Summary for CCL1    This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]
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 UniProt Comments for CCL1    CCL1: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Secreted, signal peptide; Chemokine; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cellular calcium ion homeostasis; viral reproduction; immune response; chemotaxis; signal transduction
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 Research Articles on CCL1    1. CCL1-CCR8 interaction may play a critical role in lymphocytic recruitment in IgG4-related sclerosing cholangitis and type 1 autoimmune pancreatitis, leading to duct-centred inflammation and obliterative phlebitis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CCL1 antibodyPathways associated with anti-CCL1 antibody
 Reference Product  PubMed Publications
 CCR8 antibody  >100 publications with CCL1 and CCR8
 CCR5 antibody  >23 publications with CCL1 and CCR5
 CXCR3 antibody  >13 publications with CCL1 and CXCR3
 CCR1 antibody  >13 publications with CCL1 and CCR1
 CCR3 antibody  >12 publications with CCL1 and CCR3
 CCR2 antibody  >8 publications with CCL1 and CCR2
 CCR7 antibody  >7 publications with CCL1 and CCR7
 CCR6 antibody  >6 publications with CCL1 and CCR6
 CX3CR1 antibody  >5 publications with CCL1 and CX3CR1
 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-CCL1 antibodyOrgans/Tissues associated with anti-CCL1 antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >74 publications with CCL1 and Immune System Diseases
 Inflammation Antibodies  >72 publications with CCL1 and Inflammation
 Necrosis Antibodies  >35 publications with CCL1 and Necrosis
 Lung Diseases Antibodies  >21 publications with CCL1 and Lung Diseases
 Nervous System Diseases Antibodies  >21 publications with CCL1 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >10 publications with CCL1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >6 publications with CCL1 and Liver Diseases
 Kidney Diseases Antibodies  >6 publications with CCL1 and Kidney Diseases
 Atherosclerosis Antibodies  >5 publications with CCL1 and Atherosclerosis
 Carcinoma Antibodies  >3 publications with CCL1 and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >23 publications with CCL1 and Lung
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