P22362.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,992 Da
NCBI Official Full Name
C-C motif chemokine 1
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 1
NCBI Protein Information
C-C motif chemokine 1; inflammatory cytokine I-309; T lymphocyte-secreted protein I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
UniProt Protein Name
C-C motif chemokine 1
UniProt Synonym Protein Names
Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
UniProt Synonym Gene Names
UniProt Entry Name
CCL1_HUMAN
NCBI Summary for CCL1
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]
UniProt Comments for CCL1
CCL1: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Secreted; Secreted, signal peptide; Chemokine; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q12
Cellular Component: extracellular space
Molecular Function: chemokine activity
Biological Process: cellular calcium ion homeostasis; viral reproduction; immune response; chemotaxis; signal transduction
Research Articles on CCL1
Precautions
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Disclaimer
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Products associated with anti-CCL1 antibody
Pathways associated with anti-CCL1 antibody
Diseases associated with anti-CCL1 antibody
Organs/Tissues associated with anti-CCL1 antibody
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