NP_001436.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,874 Da
NCBI Official Full Name
gastrotropin isoform 2
NCBI Official Synonym Full Names
fatty acid binding protein 6
NCBI Official Synonym Symbols
ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB [Similar Products]
NCBI Protein Information
gastrotropin
UniProt Protein Name
Gastrotropin
UniProt Synonym Protein Names
Fatty acid-binding protein 6; Ileal lipid-binding protein; ILBP; Intestinal 15 kDa protein; I-15P; Intestinal bile acid-binding protein; I-BABP
UniProt Synonym Gene Names
UniProt Entry Name
FABP6_HUMAN
NCBI Summary for I-BABP / FABP6
This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for I-BABP / FABP6
FABP6: Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. 2 isoforms of the human protein are produced by alternative promoter.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 5q33.3-q34
Cellular Component: cytoplasm; cytosol
Molecular Function: bile acid binding; lipid binding; transporter activity
Biological Process: bile acid and bile salt transport; bile acid metabolic process; lipid metabolic process; negative regulation of cell proliferation; triacylglycerol catabolic process
Research Articles on I-BABP / FABP6
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Products associated with anti-I-BABP / FABP6 antibody
Pathways associated with anti-I-BABP / FABP6 antibody
Diseases associated with anti-I-BABP / FABP6 antibody
Organs/Tissues associated with anti-I-BABP / FABP6 antibody
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