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anti-ICAM1 antibody :: Rabbit anti-Human, Rat ICAM1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS176952 anti-ICAM1 antibody
Unit / Price
0.1 mg  /  $245 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ICAM1, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-ICAM1 antibody

 Product Synonym Names    Intercellular adhesion molecule 1; intercellular adhesion molecule 1; Antigen identified by monoclonal antibody BB2 antibody; BB 2 antibody; BB2 antibody; CD 54 antibody; CD_antigen=CD54 antibody; CD54 antibody; CD54 antigen antibody; Cell surface glycoprotein P3.58 antibody; Human rhinovirus receptor antibody; ICAM 1 antibody; ICAM-1 antibody; ICAM1 antibody; ICAM1_HUMAN antibody; intercellular adhesion molecule 1(CD54); human rhinovirus receptor antibody; Intercellular adhesion molecule 1 antibody; Major group rhinovirus receptor antibody; MALA 2 antibody; MALA2 antibody; MyD 10 antibody; MyD10 antibody; P3.58 antibody; Surface antigen of activated B cells antibody; Surface antigen of activated B cells, BB2 antibody
 Product Gene Name   

anti-ICAM1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 611162
 3D Structure    ModBase 3D Structure for P05362
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Rat
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 Specificity    No cross reactivity with other proteins.
 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    NSO-derived human ICAM1 recombinant protein (Position: Q28-E480). Human ICAM1 shares 55% and 53% amino acid (aa) sequence identity with mouse and rat adiponectin, respectively.
 Contents    Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
 Relevant detection system    MBS provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit MBS176460 in WB, supported by MBS176451 in IHC (P).
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ICAM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ICAM1 antibody

   Description: Rabbit IgG polyclonal antibody for Intercellular adhesion molecule 1(ICAM1) detection. Tested with WB, IHC-P in Human.
Background: CD54, also known as ICAM-1. Intercellular adhesion molecule-1(ICAM1) is a ligand for lymphocyte function-associated(LFA) antigens. Intercellular adhesion molecule-1(ICAM-1) is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. ICAM1 protein is the major human rhinovirus receptor. ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18(Leu-CAMa, LFA-1) and its ligand CD54(ICAM-1).
 Applications Tested/Suitable for anti-ICAM1 antibody   

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

 Application Notes for anti-ICAM1 antibody    Western Blot:
Concentration: 0.1-05ug/ml
Tested Species: Hu
Predicted Species: -
Anigen Retrieval: -

Immunohistochemistry (Paraffin-embedded Section)
Concentration: 0.5-1ug/ml
Tested Species: Hu, Rat
Predicted Species: -

Anigen Retrieval: By Heat
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
by Heat: Boiling the paraffin section in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
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NCBI/Uniprot data below describe general gene information for ICAM1. It may not necessarily be applicable to this product.
 NCBI GI #    68067956
 NCBI GeneID    3383
 NCBI Accession #    P05362.2 [Other Products]
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 UniProt Primary Accession #    P05362 [Other Products]
 UniProt Secondary Accession #    Q5NKV7; Q96B50; B2R6M3 [Other Products]
 UniProt Related Accession #    P05362 [Other Products]
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 NCBI Official Full Name    Intercellular adhesion molecule 1
 NCBI Official Synonym Full Names    intercellular adhesion molecule 1
 NCBI Official Symbol    ICAM1 [Similar Products]
 NCBI Official Synonym Symbols   
BB2; CD54; P3.58
[Similar Products]
 NCBI Protein Information    intercellular adhesion molecule 1; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
 UniProt Protein Name    Intercellular adhesion molecule 1
 UniProt Synonym Protein Names   
Major group rhinovirus receptor; CD_antigen: CD54
 Protein Family    Intercellular adhesion molecule
 UniProt Gene Name    ICAM1 [Similar Products]
 UniProt Synonym Gene Names    ICAM-1 [Similar Products]
 UniProt Entry Name    ICAM1_HUMAN
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 NCBI Summary for ICAM1    This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ICAM1    ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 19p13.3-p13.2

Cellular Component: extracellular space; focal adhesion; cell surface; membrane; integral to plasma membrane; plasma membrane; immunological synapse; external side of plasma membrane

Molecular Function: viral receptor activity; integrin binding; protein binding; transmembrane receptor activity; receptor activity

Biological Process: entry of virus into host cell; extracellular matrix organization and biogenesis; positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; response to organic cyclic substance; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; leukocyte adhesion; cellular response to nutrient levels; sensory perception of sound; ovarian follicle development; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; membrane to membrane docking; response to sulfur dioxide; cell adhesion; regulation of leukocyte mediated cytotoxicity; acute inflammatory response to antigenic stimulus; response to drug; regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; regulation of immune response; cytokine and chemokine mediated signaling pathway; response to amphetamine; cell aging; response to amino acid stimulus; heterophilic cell adhesion; positive regulation of peptidyl-tyrosine phosphorylation; response to ethanol; response to copper ion; positive regulation of actin filament polymerization; positive regulation of vasoconstriction; adhesion to host; cell adhesion mediated by integrin; response to ionizing radiation; leukocyte migration

Disease: Malaria, Susceptibility To
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 Research Articles on ICAM1    1. NF-kappaB/ICAM-1 pathway induced adhesion of neutrophils and was involved in renal injury after hypoxia-ischemia injury.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ICAM1 antibodyPathways associated with anti-ICAM1 antibody
 Reference Product  PubMed Publications
 ITGB2 antibody  >879 publications with ICAM1 and ITGB2
 ITGAL antibody  >472 publications with ICAM1 and ITGAL
 ITGAM antibody  >437 publications with ICAM1 and ITGAM
 CD44 antibody  >368 publications with ICAM1 and CD44
 IL6 antibody  >146 publications with ICAM1 and IL6
 ITGAX antibody  >139 publications with ICAM1 and ITGAX
 SELE antibody  >78 publications with ICAM1 and SELE
 HLA-B antibody  >29 publications with ICAM1 and HLA-B
 DIF antibody  >3 publications with ICAM1 and DIF
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
Diseases associated with anti-ICAM1 antibodyOrgans/Tissues associated with anti-ICAM1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5522 publications with ICAM1 and Inflammation
 Necrosis Antibodies  >4728 publications with ICAM1 and Necrosis
 Cardiovascular Diseases Antibodies  >3578 publications with ICAM1 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >1433 publications with ICAM1 and Atherosclerosis
 Reperfusion Injury Antibodies  >873 publications with ICAM1 and Reperfusion Injury
 Myocardial Ischemia Antibodies  >787 publications with ICAM1 and Myocardial Ischemia
 Kidney Diseases Antibodies  >751 publications with ICAM1 and Kidney Diseases
 Liver Diseases Antibodies  >544 publications with ICAM1 and Liver Diseases
 Hypertension Antibodies  >517 publications with ICAM1 and Hypertension
 Asthma Antibodies  >500 publications with ICAM1 and Asthma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11657 publications with ICAM1 and Blood
 Vascular Antibodies  >8711 publications with ICAM1 and Vascular
 Lung Antibodies  >1750 publications with ICAM1 and Lung
 Heart Antibodies  >1266 publications with ICAM1 and Heart
 Skin Antibodies  >1191 publications with ICAM1 and Skin
 Liver Antibodies  >1171 publications with ICAM1 and Liver
 Kidney Antibodies  >1161 publications with ICAM1 and Kidney
 Brain Antibodies  >1157 publications with ICAM1 and Brain
 Muscle Antibodies  >1028 publications with ICAM1 and Muscle
 Embryonic Tissue Antibodies  >770 publications with ICAM1 and Embryonic Tissue
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