View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-ICOSLG antibody :: Rabbit ICOSLG Polyclonal Antibody Catalog # MBS2539457 Unit / Price 0.06 mL / $245 +1 FREE 8GB USB 0.12 mL / $335 +1 FREE 8GB USB 0.2 mL / $525 +1 FREE 8GB USB 5x0.2 mL / $2,345 +2 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name ICOSLG , Polyclonal Antibody Popular Item Full Product Name ICOSLG Polyclonal Antibody Product Synonym Names B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L Product Gene Name anti-ICOSLG antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP MBS2539457 Technical Datasheet Technical Datasheet PDF OMIM 605717 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Purity/Purification Affinity Purification Immunogen Recombinant protein of human ICOSLG Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3 Preparation and Storage Store at -20°C. Avoid freeze / thaw cycles. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of anti-ICOSLG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-ICOSLG antibody This gene is ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. May be play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. Applications Tested/Suitable for anti-ICOSLG antibody Western Blot (WB), Immunohistochemistry (IHC) Application Notes for anti-ICOSLG antibody WB: 1:500-1:2000IHC: 1:50-1:200 Western Blot (WB) of anti-ICOSLG antibody Western blot analysis of extracts of various cell lines using ICOSL Polyclonal Antibody at dilution of 1:1000. Immunohistochemistry (IHC) of anti-ICOSLG antibody Immunohistochemistry of paraffin-embedded Human skin carcinoma using ICOSL Polyclonal Antibody at dilution of 1:100 (40x lens). Immunohistochemistry (IHC) of anti-ICOSLG antibody Immunohistochemistry of paraffin-embedded Human kidney using ICOSL Polyclonal Antibody at dilution of 1:100 (40x lens). TOP NCBI/Uniprot data below describe general gene information for ICOSLG . It may not necessarily be applicable to this product. NCBI GI # 40352972 NCBI GeneID 23308 NCBI Accession # AAH64637.1 [Other Products] UniProt Secondary Accession # Q9HD18; Q9NRQ1; A8MUZ1[Other Products] UniProt Related Accession # O75144[Other Products] Molecular Weight Calculated MW: 20kDa/33kDa/34kDaObserved MW: 50-70kDa TOP NCBI Official Full Name ICOSLG protein NCBI Official Synonym Full Names inducible T-cell co-stimulator ligand NCBI Official Symbol ICOSLG [Similar Products] NCBI Official Synonym Symbols B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L [Similar Products] NCBI Protein Information ICOS ligand UniProt Protein Name ICOS ligand UniProt Synonym Protein Names B7 homolog 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD_antigen: CD275 UniProt Gene Name ICOSLG [Similar Products] UniProt Synonym Gene Names B7H2; B7RP1; ICOSL; KIAA0653; B7-H2; B7RP-1 [Similar Products] UniProt Entry Name ICOSL_HUMAN TOP TOP UniProt Comments for ICOSLG ICOSLG: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function. Belongs to the immunoglobulin superfamily. BTN/MOG family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 21q22.3Cellular Component: integral to membrane; plasma membraneMolecular Function: receptor bindingBiological Process: adaptive immune response; B cell activation; defense response; hyperosmotic response; positive regulation of activated T cell proliferation; signal transduction; T cell activation; T cell costimulation Research Articles on ICOSLG 1. Loss-of-function mutations in NIK cause impaired ICOSL expression. 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TOP Products associated with anti-ICOSLG antibody Reference Product PubMed Publications ICOS antibody >65 publications with ICOSLG and ICOS CD28 antibody >28 publications with ICOSLG and CD28 CTLA4 antibody >17 publications with ICOSLG and CTLA4 CXCL12 antibody >1 publications with ICOSLG and CXCL12 Pathways associated with anti-ICOSLG antibody Products by Pathway Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Costimulation By The CD28 Family Pathway antibodies Costimulation By The CD28 Family Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Intestinal Immune Network For IgA Production Pathway antibodies Intestinal Immune Network For IgA Production Pathway Diagram Intestinal Immune Network For IgA Production Pathway antibodies Intestinal Immune Network For IgA Production Pathway Diagram Diseases associated with anti-ICOSLG antibody Disease Name Pubmed Publications Necrosis Antibodies >23 publications with ICOSLG and Necrosis Autoimmune Diseases Antibodies >17 publications with ICOSLG and Autoimmune Diseases Inflammation Antibodies >16 publications with ICOSLG and Inflammation Vascular Diseases Antibodies >9 publications with ICOSLG and Vascular Diseases Asthma Antibodies >9 publications with ICOSLG and Asthma Carcinoma Antibodies >7 publications with ICOSLG and Carcinoma Celiac Disease Antibodies >4 publications with ICOSLG and Celiac Disease Colitis, Ulcerative Antibodies >3 publications with ICOSLG and Colitis, Ulcerative Carcinoma, Squamous Cell Antibodies >2 publications with ICOSLG and Carcinoma, Squamous Cell Atherosclerosis Antibodies >2 publications with ICOSLG and Atherosclerosis Organs/Tissues associated with anti-ICOSLG antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >86 publications with ICOSLG and Blood Lymph Node Antibodies >8 publications with ICOSLG and Lymph Node Lung Antibodies >6 publications with ICOSLG and Lung Brain Antibodies >6 publications with ICOSLG and Brain Liver Antibodies >5 publications with ICOSLG and Liver Skin Antibodies >5 publications with ICOSLG and Skin Kidney Antibodies >4 publications with ICOSLG and Kidney Heart Antibodies >4 publications with ICOSLG and Heart Connective Tissue Antibodies >3 publications with ICOSLG and Connective Tissue Stomach Antibodies >2 publications with ICOSLG and Stomach TOP © 2006-24 MyBioSource.com. 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