NP_071910.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
zinc finger protein Eos isoform a
NCBI Official Synonym Full Names
IKAROS family zinc finger 4
NCBI Official Synonym Symbols
NCBI Protein Information
zinc finger protein Eos
UniProt Protein Name
Zinc finger protein Eos
UniProt Synonym Protein Names
Ikaros family zinc finger protein 4
UniProt Synonym Gene Names
NCBI Summary for IKZF4
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]
UniProt Comments for IKZF4
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 ().
Research Articles on IKZF4
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Products associated with anti-IKZF4 antibody
Diseases associated with anti-IKZF4 antibody
Organs/Tissues associated with anti-IKZF4 antibody
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