NP_034684.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
interleukin-1 alpha
NCBI Official Synonym Full Names
interleukin 1 alpha
NCBI Official Synonym Symbols
NCBI Protein Information
interleukin-1 alpha; IL-1 alpha
UniProt Protein Name
Interleukin-1 alpha
UniProt Synonym Gene Names
UniProt Entry Name
IL1A_MOUSE
UniProt Comments for Il1a
IL1A: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Belongs to the IL-1 family.
Protein type: Motility/polarity/chemotaxis; Cytokine
Cellular Component: extracellular space; cell surface; plasma membrane; extracellular region; cytosol
Molecular Function: copper ion binding; interleukin-1 receptor binding; cytokine activity
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of mitosis; cytokine and chemokine mediated signaling pathway; positive regulation of interleukin-2 biosynthetic process; germ cell programmed cell death; positive regulation of interleukin-6 production; positive regulation of JNK cascade; fever; positive regulation of stress-activated MAPK cascade; negative regulation of cell proliferation; positive regulation of angiogenesis; connective tissue replacement during inflammatory response; response to copper ion; positive regulation of cell division; keratinization; positive regulation of prostaglandin secretion; positive regulation of transcription from RNA polymerase II promoter; immune response; regulation of sensory perception of pain; inflammatory response; positive regulation of cytokine secretion
Research Articles on Il1a
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Products associated with anti-Il1a antibody
Pathways associated with anti-Il1a antibody
Diseases associated with anti-Il1a antibody
Organs/Tissues associated with anti-Il1a antibody
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