View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-IL-22 antibody :: Rabbit IL-22 Polyclonal Antibody Catalog # MBS1750523 Unit / Price 0.1 mg / $460 +1 FREE 8GB USB 5x0.1 mg / $1,880 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IL-22, Polyclonal Antibody Full Product Name Anti-IL-22 Picoband Antibody Product Synonym Names Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF; IL22; ILTIF; ZCYTO18; UNQ3099/PRO10096 Product Gene Name anti-IL-22 antibody[Similar Products] Product Synonym Gene Name IL22[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM AJ277247 mRNA 3D Structure ModBase 3D Structure for Q9GZX6 Clonality Polyclonal Host Rabbit Species Reactivity Human, Mouse, RatNo cross reactivity with other proteins. Purity/Purification Immunogen affinity purified Form/Format Lyophilized Concentration Add 0.2ml of distilled water will yield a concentration of 500ug/ml. (lot specific) Immunogen E Coli-derived human IL-22 recombinant protein (Position: A34-I179). Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22. Subcellular Localization Secreted. Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml. Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Preparation and Storage Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. ISO Certification Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory. Other Notes Small volumes of anti-IL-22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-IL-22 antibody Description: Interleukin-22 (IL-22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily, a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. It also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.Protein Function: Cytokine that contributes to the inflammatory response in vivo. Product Categories/Family for anti-IL-22 antibody Immunology; Innate Immunity; Macrophage/Inflamm.; Immunology; Cytokines; Interleukins; Signal Transduction; Adapters; transmembrane Applications Tested/Suitable for anti-IL-22 antibody ELISA (EIA), Western Blot (WB) Application Notes for anti-IL-22 antibody ELISA: 0.1-0.5mug/mlWB: 0.1-0.5mug/ml Western Blot (WB) of anti-IL-22 antibody Figure 1. Western blot analysis of IL-22 using anti-IL-22 antibody (MBS1750523). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: human HepG2 whole cell lysate,Lane 2: mouse HEPA1-6 whole cell lysate,Lane 3: rat PC-12 whole cell lysate, After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-IL-22 antigen affinity purified polyclonal antibody at 0.5ug/mL overnight at 4 degree C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for IL-22 at approximately 22KD. The expected band size for IL-22 is at 20KD. TOP NCBI/Uniprot data below describe general gene information for IL-22. It may not necessarily be applicable to this product. NCBI GI # 10092625 NCBI GeneID 50616 NCBI Accession # NP_065386.1 [Other Products] NCBI GenBank Nucleotide # NM_020525.4 [Other Products] UniProt Primary Accession # Q9GZX6 [Other Products] UniProt Related Accession # Q9GZX6[Other Products] Molecular Weight 20011 MW TOP NCBI Official Full Name interleukin-22 NCBI Official Synonym Full Names interleukin 22 NCBI Official Symbol IL22 [Similar Products] NCBI Official Synonym Symbols TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23 [Similar Products] NCBI Protein Information interleukin-22 UniProt Protein Name Interleukin-22 UniProt Synonym Protein Names Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF UniProt Gene Name IL22 [Similar Products] UniProt Synonym Gene Names ILTIF; ZCYTO18; IL-22; IL-TIF [Similar Products] TOP TOP UniProt Comments for IL-22 Cytokine that contributes to the inflammatory response in vivo. Research Articles on IL-22 1. TARC production in HaCaT keratinocytes through the interaction between IL-22 and IL-22Ralpha facilitates T-cell migration in atopic dermatitis caused by house dust mites. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-IL-22 antibody Reference Product PubMed Publications STAT3 antibody >7 publications with IL-22 and STAT3 IL23A antibody >3 publications with IL-22 and IL23A IL22RA1 antibody >3 publications with IL-22 and IL22RA1 STAT1 antibody >2 publications with IL-22 and STAT1 IL10RB antibody >2 publications with IL-22 and IL10RB IL21R antibody >1 publications with IL-22 and IL21R Pathways associated with anti-IL-22 antibody Products by Pathway Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Inflammatory Bowel Disease Pathway antibodies Inflammatory Bowel Disease Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram Diseases associated with anti-IL-22 antibody Disease Name Pubmed Publications Inflammation Antibodies >15 publications with IL-22 and Inflammation Immune System Diseases Antibodies >10 publications with IL-22 and Immune System Diseases Autoimmune Diseases Antibodies >10 publications with IL-22 and Autoimmune Diseases Colitis Antibodies >5 publications with IL-22 and Colitis Weight Loss Antibodies >2 publications with IL-22 and Weight Loss Lung Diseases Antibodies >2 publications with IL-22 and Lung Diseases Drug Toxicity Antibodies >2 publications with IL-22 and Drug Toxicity Immunologic Deficiency Syndromes Antibodies >1 publications with IL-22 and Immunologic Deficiency Syndromes Necrosis Antibodies >1 publications with IL-22 and Necrosis Organs/Tissues associated with anti-IL-22 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >35 publications with IL-22 and Blood TOP © 2006-24 MyBioSource.com. 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