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anti-IL13 antibody :: Rabbit anti-Rat IL13 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS175604
Testing Data
Unit / Price
0.1 mg  /  $245 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL13, Polyclonal Antibody

 Also Known As   

Anti-IL13 antibody

 Product Synonym Names    Interleukin-13(IL-13); interleukin 13; Allergic rhinitis antibody; ALRH antibody; BHR1 antibody; Bronchial hyperresponsiveness 1(bronchial asthma) antibody; IL 13 antibody; IL-13 antibody; Il13 antibody; IL13_HUMAN antibody; Interleukin 13 antibody; Interleukin-13 antibody; MGC116786 antibody; MGC116788 antibody; MGC116789 antibody; NC30 antibody; P600 antibody
 Product Gene Name   

anti-IL13 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P42203
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Rat
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 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    A synthetic peptide corresponding to a sequence in the middle region of rat IL13 (80-102aa CNAIHRTQRILNGLCNQKASDVA).
 Contents    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-IL13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-IL13 antibody

   Description: Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB in Rat.
Background: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is cytokine secreted by many cell types, but especially T helper type 2(Th2) cells that is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor(IL-4Ralpha) and at least one of two known IL-13-specific binding chains. IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
 Applications Tested/Suitable for anti-IL13 antibody   

Western Blot (WB)

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 Testing Data of anti-IL13 antibody    anti-IL13 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for IL13. It may not necessarily be applicable to this product.
 NCBI GI #    1170528
 NCBI GeneID    116553
 NCBI Accession #    P42203.1 [Other Products]
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 UniProt Primary Accession #    P42203 [Other Products]
 UniProt Related Accession #    P42203 [Other Products]
 Molecular Weight    14,093 Da
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 NCBI Official Full Name    Interleukin-13
 NCBI Official Synonym Full Names    interleukin 13
 NCBI Official Symbol    Il13 [Similar Products]
 NCBI Protein Information    interleukin-13; IL-13; T-cell activation protein P600
 UniProt Protein Name    Interleukin-13
 UniProt Synonym Protein Names   
T-cell activation protein P600
 Protein Family    Interleukin
 UniProt Gene Name    Il13 [Similar Products]
 UniProt Synonym Gene Names    Il-13; IL-13 [Similar Products]
 UniProt Entry Name    IL13_RAT
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 NCBI Summary for IL13    cytokine; involved in inflammatory and immune responses [RGD, Feb 2006]
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 UniProt Comments for IL13    IL13: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. Belongs to the IL-4/IL-13 family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; cytoplasm; extracellular region; external side of plasma membrane

Molecular Function: interleukin-13 receptor binding; cytokine activity

Biological Process: response to nicotine; positive regulation of smooth muscle cell proliferation; microglial cell activation; regulation of proton transport; response to lipopolysaccharide; positive regulation of mast cell degranulation; positive regulation of connective tissue growth factor production; positive regulation of tyrosine phosphorylation of Stat6 protein; positive regulation of immunoglobulin production; response to ethanol; positive regulation of protein secretion; response to mechanical stimulus; positive regulation of B cell proliferation; positive regulation of ion transport; immune response; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of NAD(P)H oxidase activity; inflammatory response; positive regulation of macrophage activation
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 Research Articles on IL13    1. IL-13 significantly enhanced C/EBP-alpha/COX-2 expression and PGE2 production in LPS-treated microglial cells. Paradoxically, IL-13 abolished C/EBP-beta/PPAR-gamma/HO-1 expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL13 antibodyPathways associated with anti-IL13 antibody
 Reference Product  PubMed Publications
 Il4ra antibody  >866 publications with IL13 and Il4ra
 Stat6 antibody  >412 publications with IL13 and Stat6
 Il13ra1 antibody  >294 publications with IL13 and Il13ra1
 Il5 antibody  >111 publications with IL13 and Il5
 Il15 antibody  >60 publications with IL13 and Il15
 Il2 antibody  >55 publications with IL13 and Il2
 Nos2 antibody  >38 publications with IL13 and Nos2
 Il9 antibody  >27 publications with IL13 and Il9
 Csf2 antibody  >12 publications with IL13 and Csf2
 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with anti-IL13 antibody
 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >1376 publications with IL13 and Hypersensitivity
 Respiratory Tract Diseases Antibodies  >1346 publications with IL13 and Respiratory Tract Diseases
 Inflammation Antibodies  >1318 publications with IL13 and Inflammation
 Asthma Antibodies  >1273 publications with IL13 and Asthma
 Hypersensitivity, Immediate Antibodies  >1197 publications with IL13 and Hypersensitivity, Immediate
 Lung Diseases Antibodies  >1178 publications with IL13 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >1000 publications with IL13 and Respiratory Hypersensitivity
 Necrosis Antibodies  >631 publications with IL13 and Necrosis
 Fibrosis Antibodies  >326 publications with IL13 and Fibrosis
 Bronchial Hyperreactivity Antibodies  >233 publications with IL13 and Bronchial Hyperreactivity
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