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anti-IL23R antibody :: Rabbit IL23R Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS854115
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL23R, Polyclonal Antibody

 Also Known As   

IL23R Antibody

 Product Gene Name   

anti-IL23R antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607562
 3D Structure    ModBase 3D Structure for Q5VWK5
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Predicted: Mouse, Rat
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 Form/Format    Purified by protein A column containing 0.02% NaN3
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-IL23R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-IL23R antibody

   Rabbit polyclonal IL23R (1) antibody was raised against a recombinate human IL23R protein 1-227aa (BC040720).
 Product Categories/Family for anti-IL23R antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-IL23R antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-IL23R antibody    ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
IHC: 1:100-1:500
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 Testing Data of anti-IL23R antibody    anti-IL23R antibody Testing Data image
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 Testing Data of anti-IL23R antibody    anti-IL23R antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for IL23R. It may not necessarily be applicable to this product.
 NCBI GI #    24430212
 NCBI GeneID    149233
 NCBI Accession #    NP_653302.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_144701.2 [Other Products]
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 UniProt Primary Accession #    Q5VWK5 [Other Products]
 UniProt Secondary Accession #    Q4VGP1; Q4VGP2; Q4VGP3; Q4VGP4; Q4VGP5; Q4VGP6; Q5VWK7; Q8IW84; Q8NFQ9; Q96AS1; C9JGX4 [Other Products]
 UniProt Related Accession #    Q5VWK5 [Other Products]
 Molecular Weight    25,551 Da
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 NCBI Official Full Name    interleukin-23 receptor
 NCBI Official Synonym Full Names    interleukin 23 receptor
 NCBI Official Symbol    IL23R [Similar Products]
 NCBI Protein Information    interleukin-23 receptor
 UniProt Protein Name    Interleukin-23 receptor
 Protein Family    Interleukin-23 receptor
 UniProt Gene Name    IL23R [Similar Products]
 UniProt Synonym Gene Names    IL-23 receptor; IL-23R [Similar Products]
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 NCBI Summary for IL23R    The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL23R    Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
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Product References and Citations for anti-IL23R antibody

   (1) Anderson, C.A., Boucher, G., Lees, C.W., et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat. Genet. 43 (3), 246-252 (2011).
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 Research Articles on IL23R    1. Findings indicate that IL17A -197 G/A and IL23R H3Q are not associated with susceptibility to MM. However, IL-17 and IL-23R polymorphisms may affect severity, bone lesions, and extra-medullary disease in patients with MM.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-IL23R antibodyDiseases associated with anti-IL23R antibody
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL23-mediated Signaling Events Pathway antibodies  IL23-mediated Signaling Events Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammatory Bowel Diseases Antibodies  >169 publications with IL23R and Inflammatory Bowel Diseases
 Crohn Disease Antibodies  >118 publications with IL23R and Crohn Disease
 Arthritis Antibodies  >84 publications with IL23R and Arthritis
 Colitis, Ulcerative Antibodies  >80 publications with IL23R and Colitis, Ulcerative
 Psoriasis Antibodies  >68 publications with IL23R and Psoriasis
 Inflammation Antibodies  >65 publications with IL23R and Inflammation
 Spondylitis, Ankylosing Antibodies  >49 publications with IL23R and Spondylitis, Ankylosing
 Inflammatory Bowel Disease 17 Antibodies  >38 publications with IL23R and Inflammatory Bowel Disease 17
 Necrosis Antibodies  >20 publications with IL23R and Necrosis
 Liver Diseases Antibodies  >6 publications with IL23R and Liver Diseases
Organs/Tissues associated with anti-IL23R antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >27 publications with IL23R and Skin
 Bone Marrow Antibodies  >5 publications with IL23R and Bone Marrow
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