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anti-IL31 antibody :: Rabbit anti-Human, Mouse IL31 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS240345
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL31, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human IL31

 Product Synonym Names    Anti-IL31 Antibody (Internal) IHC-plus; IL31; IL-31; Interleukin 31; Interleukin-31; Human IL31
 Product Gene Name   

anti-IL31 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609509
 3D Structure    ModBase 3D Structure for Q6EBC2
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    18 amino acid peptide from near the center of human IL-31
 Purity/Purification    Affinity Purified
 Form/Format    PBS, 0.02% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human IL31 / IL-31.
 Immunogen Type    Synthetic peptide
 Immunogen    IL31 antibody was raised against synthetic peptide from human IL31 / IL-31.
 Antigen Modification    Internal
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 Preparation and Storage    Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
 Other Notes    Small volumes of anti-IL31 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-IL31 antibody    Family: Interleukin
 Applications Tested/Suitable for anti-IL31 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-IL31 antibody    IHC-P (5 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
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 Immunohistochemistry (IHC) of anti-IL31 antibody    Anti-IL-31 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-IL31 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-IL31 antibody    Immunofluorescence of IL-31 in Human Skeletal Muscle cells with IL-31 antibody at 20 ug/ml.
anti-IL31 antibody Immunofluorescence (IF) image
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 Western Blot (WB) of anti-IL31 antibody    Western blot of IL-31 in human skeletal muscle tissue lysate with IL-31 antibody at (A) 2.5, (B) 5 and (C) 10 ug/ml.
anti-IL31 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for IL31. It may not necessarily be applicable to this product.
 NCBI GI #    62122911
 NCBI GeneID    386653
 NCBI Accession #    NP_001014358.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001014336.1 [Other Products]
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 UniProt Primary Accession #    Q6EBC2 [Other Products]
 UniProt Secondary Accession #    A2RUQ1 [Other Products]
 UniProt Related Accession #    Q6EBC2 [Other Products]
 Molecular Weight    18,205 Da
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 NCBI Official Full Name    interleukin-31
 NCBI Official Synonym Full Names    interleukin 31
 NCBI Official Symbol    IL31 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    interleukin-31
 UniProt Protein Name    Interleukin-31
 Protein Family    Interleukin
 UniProt Gene Name    IL31 [Similar Products]
 UniProt Synonym Gene Names    IL-31 [Similar Products]
 UniProt Entry Name    IL31_HUMAN
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 NCBI Summary for IL31    IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for IL31    IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.

Protein type: Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: immune system process
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 Research Articles on IL31    1. IL-31-positive cells were observed as mononuclear infiltrating cells and as CD11b co-expressing cells in severe atopic dermatitis samples.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL31 antibodyDiseases associated with anti-IL31 antibody
 Reference Product  PubMed Publications
 IL31RA antibody  >15 publications with IL31 and IL31RA
 OSMR antibody  >8 publications with IL31 and OSMR
 IL6ST antibody  >1 publications with IL31 and IL6ST
 Disease Name  Pubmed Publications
 Dermatitis Antibodies  >48 publications with IL31 and Dermatitis
 Dermatitis, Atopic Antibodies  >43 publications with IL31 and Dermatitis, Atopic
 Hypersensitivity Antibodies  >42 publications with IL31 and Hypersensitivity
 Inflammation Antibodies  >23 publications with IL31 and Inflammation
 Lung Diseases Antibodies  >7 publications with IL31 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >6 publications with IL31 and Respiratory Hypersensitivity
 Dermatitis, Contact Antibodies  >5 publications with IL31 and Dermatitis, Contact
 Necrosis Antibodies  >3 publications with IL31 and Necrosis
 Brain Diseases Antibodies  >3 publications with IL31 and Brain Diseases
 Melanoma Antibodies  >2 publications with IL31 and Melanoma
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