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anti-IDO2 antibody :: Goat INDOL1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422084
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

INDOL1 (IDO2), Polyclonal Antibody

 Also Known As   

Goat anti-INDOL1 Antibody

 Product Synonym Names    IDO2; indoleamine 2,3-dioxygenase 2; INDOL1; indoleamine 2,3-dioxygenase-like 1 protein; indoleamine-pyrrole 2,3 dioxygenase-like 1; IDO2 antibody; indoleamine 2; 3-dioxygenase 2 antibody; INDOL1 antibody; indoleamine 2; 3-dioxygenase-like 1 protein antibody; indoleamine-pyrrole 2; 3 dioxygenase-like 1 antibody; INDOL1
 Product Gene Name   

anti-IDO2 antibody

[Similar Products]
 Product Synonym Gene Name    INDOL1 [Similar Products]
 Antibody/Peptide Pairs    INDOL1 peptide (MBS425839) is used for blocking the activity of INDOL1 antibody (MBS422084)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    RDKTLESILH PR
 OMIM    612129
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Dog, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-RDKTLESILHPR, from the C Terminus of the protein sequence according to NP_919270.2.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-IDO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IDO2 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-IDO2 antibody    Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 50kDa band observed in Human Kidney lysates (calculated MW of 47. 07kDa according to NP_919270.2). Recommended concentration: 1-3ug/ml.
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 Western Blot (WB) of anti-IDO2 antibody    (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
anti-IDO2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for IDO2. It may not necessarily be applicable to this product.
 NCBI GI #    148539554
 NCBI GeneID    169355
 NCBI Accession #    NP_919270.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_194294.2 [Other Products]
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 UniProt Secondary Accession #    A4UD41; F5H5G0 [Other Products]
 UniProt Related Accession #    Q6ZQW0 [Other Products]
 Molecular Weight    19,610 Da
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 NCBI Official Full Name    indoleamine 2,3-dioxygenase 2
 NCBI Official Synonym Full Names    indoleamine 2,3-dioxygenase 2
 NCBI Official Symbol    IDO2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    indoleamine 2,3-dioxygenase 2
 UniProt Protein Name    Indoleamine 2,3-dioxygenase 2
 UniProt Synonym Protein Names   
Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
 Protein Family    Indoleamine 2,3-dioxygenase
 UniProt Gene Name    IDO2 [Similar Products]
 UniProt Synonym Gene Names    INDOL1; IDO-2 [Similar Products]
 UniProt Entry Name    I23O2_HUMAN
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 NCBI Summary for IDO2    Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
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 UniProt Comments for IDO2    INDOL1: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Belongs to the indoleamine 2,3-dioxygenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - tryptophan; EC 1.13.11.-; Oxidoreductase

Chromosomal Location of Human Ortholog: 8p11.21

Cellular Component: cytoplasm; cytosol

Molecular Function: heme binding; indoleamine 2,3-dioxygenase activity; metal ion binding; tryptophan 2,3-dioxygenase activity

Biological Process: immune system process; tryptophan catabolic process; tryptophan catabolic process to kynurenine
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 Research Articles on IDO2    1. functional importance of IDO enzymes in human Crohn's disease
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IDO2 antibodyPathways associated with anti-IDO2 antibody
 Reference Product  PubMed Publications
 TPH1 antibody  >1 publications with IDO2 and TPH1
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway antibodies  Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway Diagram
 L-kynurenine Degradation Pathway antibodies  L-kynurenine Degradation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 NAD De Novo Biosynthesis Pathway antibodies  NAD De Novo Biosynthesis Pathway Diagram
 Tryptophan Catabolism Pathway antibodies  Tryptophan Catabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
Diseases associated with anti-IDO2 antibodyOrgans/Tissues associated with anti-IDO2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with IDO2 and Inflammation
 Disease Models, Animal Antibodies  >7 publications with IDO2 and Disease Models, Animal
 Lung Diseases Antibodies  >2 publications with IDO2 and Lung Diseases
 Cognition Disorders Antibodies  >2 publications with IDO2 and Cognition Disorders
 Necrosis Antibodies  >2 publications with IDO2 and Necrosis
 Liver Diseases Antibodies  >1 publications with IDO2 and Liver Diseases
 Uterine Cervical Neoplasms Antibodies  >1 publications with IDO2 and Uterine Cervical Neoplasms
 Vascular Diseases Antibodies  >1 publications with IDO2 and Vascular Diseases
 Kidney Diseases Antibodies  >1 publications with IDO2 and Kidney Diseases
 Weight Loss Antibodies  >1 publications with IDO2 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with IDO2 and Brain
 Liver Antibodies  >4 publications with IDO2 and Liver
 Mixed Antibodies  >2 publications with IDO2 and Mixed
 Uterus Antibodies  >1 publications with IDO2 and Uterus
 Placenta Antibodies  >1 publications with IDO2 and Placenta
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