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anti-ITGA11 antibody :: Rabbit anti-Human, Mouse ITGA11 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2523728
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ITGA11, Polyclonal Antibody

★Popular Item★
 Also Known As   

ITGA11 Polyclonal Antibody

 Product Synonym Names    HsT18964; RP11-709B3.2
 Product Gene Name   

anti-ITGA11 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2523728 Technical Datasheet    Technical Datasheet PDF
 OMIM    604789
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity purification
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 Immunogen    Synthetic peptide of human ITGA11
 Calculated MW    133kDa
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ITGA11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ITGA11 antibody

   This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.
 Applications Tested/Suitable for anti-ITGA11 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ITGA11 antibody    WB: 1:200-1:1000
IHC: 1:50-1:200
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 Western Blot (WB) of anti-ITGA11 antibody    Western Blot analysis of Mouse skeletal muscle tissue using ITGA11 Polyclonal Antibody at dilution of 1:200
anti-ITGA11 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ITGA11 antibody    Immunohistochemistry of paraffin-embedded Human liver cancer using ITGA11 Polyclonal Antibody at dilution of 1:40
anti-ITGA11 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ITGA11 antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer using ITGA11 Polyclonal Antibody at dilution of 1:40
anti-ITGA11 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ITGA11. It may not necessarily be applicable to this product.
 NCBI GI #    52485853
 NCBI GeneID    22801
 NCBI Accession #    NP_001004439 [Other Products]
 NCBI GenBank Nucleotide #    NM_001004439.1 [Other Products]
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 UniProt Secondary Accession #    Q8WYI8; Q9UKQ1; J3KQM2 [Other Products]
 UniProt Related Accession #    Q9UKX5 [Other Products]
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 NCBI Official Full Name    integrin alpha-11
 NCBI Official Synonym Full Names    integrin, alpha 11
 NCBI Official Symbol    ITGA11 [Similar Products]
 NCBI Official Synonym Symbols   
HsT18964
[Similar Products]
 NCBI Protein Information    integrin alpha-11
 UniProt Protein Name    Integrin alpha-11
 Protein Family    Integrin
 UniProt Gene Name    ITGA11 [Similar Products]
 UniProt Entry Name    ITA11_HUMAN
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 NCBI Summary for ITGA11    This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ITGA11    ITGA11: Integrin alpha-11/beta-1 is a receptor for collagen. Belongs to the integrin alpha chain family.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q23

Cellular Component: focal adhesion; membrane; plasma membrane; integrin complex

Molecular Function: collagen binding; metal ion binding

Biological Process: substrate-bound cell migration; osteoblast differentiation; integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; muscle development; cell-matrix adhesion; cell adhesion mediated by integrin; cell adhesion
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 Research Articles on ITGA11    1. Interactions between alpha11 integrins and the Smad-dependent TGF-beta2 signalling may contribute to the formation of pro-fibrotic myofibroblasts and the development of a fibrotic interstitium in diabetic cardiomyopathy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ITGA11 antibodyPathways associated with anti-ITGA11 antibody
 Reference Product  PubMed Publications
 COL11A1 antibody  >2 publications with ITGA11 and COL11A1
 COL1A2 antibody  >1 publications with ITGA11 and COL1A2
 ITGB1 antibody  >1 publications with ITGA11 and ITGB1
 Products by Pathway  Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with anti-ITGA11 antibodyOrgans/Tissues associated with anti-ITGA11 antibody
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >2 publications with ITGA11 and Heart Diseases
 Fibrosis Antibodies  >2 publications with ITGA11 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >5 publications with ITGA11 and Muscle
 Connective Tissue Antibodies  >3 publications with ITGA11 and Connective Tissue
 Embryonic Tissue Antibodies  >3 publications with ITGA11 and Embryonic Tissue
 Bone Antibodies  >3 publications with ITGA11 and Bone
 Uterus Antibodies  >2 publications with ITGA11 and Uterus
 Skin Antibodies  >2 publications with ITGA11 and Skin
 Mouth Antibodies  >1 publications with ITGA11 and Mouth
 Ovary Antibodies  >1 publications with ITGA11 and Ovary
 Spleen Antibodies  >1 publications with ITGA11 and Spleen
 Cervix Antibodies  >1 publications with ITGA11 and Cervix
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