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Add To Compare List anti-ITGB5 antibody :: Rabbit ITGB5 Polyclonal Antibody Catalog # MBS9607619 Unit / Price 0.1 mL / $270 +1 FREE 8GB USB 0.2 mL / $315 +1 FREE 8GB USB 5x0.2 mL / $1,245 +1 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name ITGB5, Polyclonal Antibody Popular Item Full Product Name ITGB5 Antibody Product Synonym Names FLJ26658; Integrin beta-5; Integrin subunit beta 5; integrin, beta 5; ITB5_HUMAN; Itgb5; Testis secretory sperm-binding protein Li 217p Product Gene Name anti-ITGB5 antibody[Similar Products] Antibody/Peptide Pairs Integrin beta 5 peptide (MBS9626332) is used for blocking the activity of Integrin beta 5 antibody (MBS9607619) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP 3D Structure ModBase 3D Structure for P18084 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Specificity ITGB5 antibody detects endogenous levels of total ITGB5 Purity/Purification The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin. Form/Format LiquidPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Concentration 1mg/ml (lot specific) Immunogen A synthesized peptide derived from human ITGB5 Subcellular Location Membrane. Conjugation Unconjugated Preparation and Storage Store at -20 degree C. Stable for 12 months from date of receipt. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Supply Chain Verification Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire. Other Notes Small volumes of anti-ITGB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-ITGB5 antibody Function: Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.Subunit Structure: Heterodimer of an alpha and a beta subunit. Beta-5 (ITGB5) associates with alpha-V (ITGAV). Interacts with MYO10 (PubMed:15156152). Interacts with DAB2. Integrin ITGAV:ITGB5 interacts with FBLN5 (via N-terminus) (By similarity). ITGAV:ITGB5 interacts with NOV (PubMed:15611078).Similarity: Belongs to the integrin beta chain family. Applications Tested/Suitable for anti-ITGB5 antibody Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) Application Notes for anti-ITGB5 antibody WB: 1:500-1:2000IHC: 1:50-1:200IF/ICC: 1:100-1:500 Immunohistochemistry (IHC) of anti-ITGB5 antibody MBS9607619 at 1/100 staining Human pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western Blot (WB) of anti-ITGB5 antibody Western blot analysis of Hela cell lysate, using ITGB5 Antibody. The lane on the left is treated with the antigen-specific peptide. Immunofluorescence (IF) of anti-ITGB5 antibody MBS9607619 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. TOP NCBI/Uniprot data below describe general gene information for ITGB5. It may not necessarily be applicable to this product. NCBI GI # 20127446 NCBI GeneID 3693 NCBI Accession # NP_002204.2 [Other Products] NCBI GenBank Nucleotide # NM_002213.4 [Other Products] UniProt Primary Accession # P18084 [Other Products] UniProt Secondary Accession # B0LPF8; B2RD70[Other Products] UniProt Related Accession # P18084[Other Products] Molecular Weight Observed: 88 kDaPredicted: 89 kDa TOP NCBI Official Full Name integrin beta-5 isoform a NCBI Official Synonym Full Names integrin subunit beta 5 NCBI Official Symbol ITGB5 [Similar Products] NCBI Protein Information integrin beta-5 UniProt Protein Name Integrin beta-5 Protein Family Integrin UniProt Gene Name ITGB5 [Similar Products] TOP NCBI Summary for ITGB5 This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017] TOP UniProt Comments for ITGB5 Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.(Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C. Research Articles on ITGB5 1. Findings indicate integrin inhibition as a promising strategy to block both aryl hydrocarbon receptor (AhR) and transforming growth factor beta (TGF-beta)-controlled features of malignancy in glioblastoma. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-ITGB5 antibody Reference Product PubMed Publications ITGAV antibody >5 publications with ITGB5 and ITGAV ITGA5 antibody >3 publications with ITGB5 and ITGA5 TLN1 antibody >1 publications with ITGB5 and TLN1 Pathways associated with anti-ITGB5 antibody Products by Pathway Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Antigen Processing-Cross Presentation Pathway antibodies Antigen Processing-Cross Presentation Pathway Diagram Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway antibodies Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway Diagram Dilated Cardiomyopathy Pathway antibodies Dilated Cardiomyopathy Pathway Diagram Dilated Cardiomyopathy Pathway antibodies Dilated Cardiomyopathy Pathway Diagram ECM-receptor Interaction Pathway antibodies ECM-receptor Interaction Pathway Diagram Diseases associated with anti-ITGB5 antibody Disease Name Pubmed Publications Neoplasms Antibodies >9 publications with ITGB5 and Neoplasms Neoplasm Metastasis Antibodies >2 publications with ITGB5 and Neoplasm Metastasis Inflammation Antibodies >2 publications with ITGB5 and Inflammation Breast Neoplasms Antibodies >1 publications with ITGB5 and Breast Neoplasms Anemia Antibodies >1 publications with ITGB5 and Anemia Neoplasms, Experimental Antibodies >1 publications with ITGB5 and Neoplasms, Experimental Lung Diseases Antibodies >1 publications with ITGB5 and Lung Diseases Organs/Tissues associated with anti-ITGB5 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >8 publications with ITGB5 and Blood Uterus Antibodies >4 publications with ITGB5 and Uterus Placenta Antibodies >4 publications with ITGB5 and Placenta Vascular Antibodies >3 publications with ITGB5 and Vascular Bone Marrow Antibodies >2 publications with ITGB5 and Bone Marrow Stomach Antibodies >2 publications with ITGB5 and Stomach Bone Antibodies >2 publications with ITGB5 and Bone Lung Antibodies >2 publications with ITGB5 and Lung Muscle Antibodies >1 publications with ITGB5 and Muscle Prostate Antibodies >1 publications with ITGB5 and Prostate TOP © 2006-24 MyBioSource.com. 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