View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-IgG3 antibody :: Sheep IgG3 Polyclonal Antibody Catalog # MBS222075 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IgG3, Polyclonal Antibody Popular Item Full Product Name SHEEP ANTI HUMAN IgG3 Product Gene Name anti-IgG3 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 147120 3D Structure ModBase 3D Structure for P01860 Clonality Polyclonal Isotype IgG Host Sheep Specificity Sheep anti human IgG3 antibody recognizes Human IgG3, generating single precipitin arcs in immunodiffusion experiments against purified human IgG3K and against human serum. Sheep anti Human IgG3 antibody does not demonstrate cross reactivity against human IgG1, IgG2 or IgG4, all bearing & kappa light chains, as assessed by western blotting. Form/Format Purified IgG - liquid Concentration IgG concentration 1.0mg/ml (lot specific) Perservative Stabilisers 0.09 % Sodium Azide (NaN3)0.1 % EACA0.01 % Benzamidine1 mM EDTA Immunogen Purified Human IgG3 Buffer Solution Glycine buffered saline Antiserum Preparation Antisera prepared by immunisation of sheep with purified human IgG3. Purified IgG was prepared by affinity chromatography. Target Species Human Preparation and Storage Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.Shelf Life: 18 months from date of despatch. Other Notes Small volumes of anti-IgG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-IgG3 antibody This product recognizes Human IgG3. Applications Tested/Suitable for anti-IgG3 antibody ELISA (EIA), Western Blot (WB) Application Notes for anti-IgG3 antibody ELISA: 1/3000-1/6000;Western Blotting: 1/2500-1/5000 TOP NCBI/Uniprot data below describe general gene information for IgG3. It may not necessarily be applicable to this product. NCBI GI # 193806361 NCBI GeneID 3502 NCBI Accession # P01860.2 [Other Products] UniProt Primary Accession # P01860 [Other Products] UniProt Secondary Accession # A2NU35[Other Products] UniProt Related Accession # P01860[Other Products] Molecular Weight 41,287 Da TOP NCBI Official Full Name Ig gamma-3 chain C region NCBI Official Synonym Full Names immunoglobulin heavy constant gamma 3 (G3m marker) NCBI Official Symbol IGHG3 [Similar Products] NCBI Official Synonym Symbols IgG3 [Similar Products] UniProt Protein Name Ig gamma-3 chain C region UniProt Synonym Protein Names HDC; Heavy chain disease protein UniProt Gene Name IGHG3 [Similar Products] UniProt Entry Name IGHG3_HUMAN TOP TOP UniProt Comments for IgG3 IGHG3: Dimer linked by 12 disulfide bonds; it has an extra interchain disulfide bond at position 7 in addition to the 11 normally present in the hinge region.Chromosomal Location of Human Ortholog: 14q32.33Cellular Component: extracellular space; extracellular regionMolecular Function: antigen bindingBiological Process: retinal homeostasis; innate immune response; complement activation, classical pathway; complement activation Research Articles on IgG3 1. Immunoglobulin (Ig) GM genes - genetic markers of IgG heavy chains located on chromosome 14 - are functional risk and protective factors for AD. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-IgG3 antibody Reference Product PubMed Publications IGLJ3 antibody >3 publications with IgG3 and IGLJ3 Pathways associated with anti-IgG3 antibody Products by Pathway Pathway Diagram Classical Antibody-mediated Complement Activation Pathway antibodies Classical Antibody-mediated Complement Activation Pathway Diagram Complement Cascade Pathway antibodies Complement Cascade Pathway Diagram Creation Of C4 And C2 Activators Pathway antibodies Creation Of C4 And C2 Activators Pathway Diagram FCGR Activation Pathway antibodies FCGR Activation Pathway Diagram Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram IL4-mediated Signaling Events Pathway antibodies IL4-mediated Signaling Events Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Initial Triggering Of Complement Pathway antibodies Initial Triggering Of Complement Pathway Diagram Innate Immune System Pathway antibodies Innate Immune System Pathway Diagram Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram Organs/Tissues associated with anti-IgG3 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >9 publications with IgG3 and Blood Skin Antibodies >3 publications with IgG3 and Skin Nerve Antibodies >3 publications with IgG3 and Nerve Lung Antibodies >3 publications with IgG3 and Lung Vascular Antibodies >2 publications with IgG3 and Vascular Uncharacterized Tissue Antibodies >2 publications with IgG3 and Uncharacterized Tissue Prostate Antibodies >1 publications with IgG3 and Prostate Muscle Antibodies >1 publications with IgG3 and Muscle Bone Antibodies >1 publications with IgG3 and Bone Bone Marrow Antibodies >1 publications with IgG3 and Bone Marrow TOP © 2006-24 MyBioSource.com. 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