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anti-IDO2 antibody :: Rabbit anti-Human Indoleamine 2,3-dioxygenase 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1499194
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Indoleamine 2,3-dioxygenase 2 (IDO2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Indoleamine 2, 3-dioxygenase 2 polyclonal Antibody

 Product Synonym Names    Indoleamine 2; 3-dioxygenase-like protein 1; Indoleamine-pyrrole 2; 3-dioxygenase-like protein 1; INDOL1; IDO2
 Product Gene Name   

anti-IDO2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612129
 3D Structure    ModBase 3D Structure for Q6ZQW0
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Indoleamine 2,3-dioxygenase 2 protein(1-407aa)
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-87164 / sc-87165 / sc-292211
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-IDO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-IDO2 antibody

   Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism.
 Applications Tested/Suitable for anti-IDO2 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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 Immunohistochemistry (IHC) of anti-IDO2 antibody    Immunohistochemistry of paraffin-embedded human liver tissue using MBS1499194 at dilution 1:100
anti-IDO2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IDO2 antibody    Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1499194 at dilution 1:100
anti-IDO2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IDO2 antibody    Immunofluorescent analysis of A549 cells using MBS1499194 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-IDO2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for IDO2. It may not necessarily be applicable to this product.
 NCBI GI #    148539554
 NCBI GeneID    169355
 NCBI Accession #    NP_919270.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_194294.2 [Other Products]
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 UniProt Primary Accession #    Q6ZQW0 [Other Products]
 UniProt Secondary Accession #    A4UD41; F5H5G0 [Other Products]
 UniProt Related Accession #    Q6ZQW0 [Other Products]
 Molecular Weight    19,610 Da [Similar Products]
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 NCBI Official Full Name    indoleamine 2,3-dioxygenase 2
 NCBI Official Synonym Full Names    indoleamine 2,3-dioxygenase 2
 NCBI Official Symbol    IDO2 [Similar Products]
 NCBI Official Synonym Symbols   
INDOL1
[Similar Products]
 NCBI Protein Information    indoleamine 2,3-dioxygenase 2
 UniProt Protein Name    Indoleamine 2,3-dioxygenase 2
 UniProt Synonym Protein Names   
Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
 Protein Family    Indoleamine 2,3-dioxygenase
 UniProt Gene Name    IDO2 [Similar Products]
 UniProt Synonym Gene Names    INDOL1; IDO-2 [Similar Products]
 UniProt Entry Name    I23O2_HUMAN
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 NCBI Summary for IDO2    Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
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 UniProt Comments for IDO2    INDOL1: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Belongs to the indoleamine 2,3-dioxygenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - tryptophan; Oxidoreductase; EC 1.13.11.-

Chromosomal Location of Human Ortholog: 8p11.21

Cellular Component: cytoplasm; cytosol

Molecular Function: heme binding; indoleamine 2,3-dioxygenase activity; metal ion binding; tryptophan 2,3-dioxygenase activity

Biological Process: immune system process; tryptophan catabolic process; tryptophan catabolic process to kynurenine
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 Research Articles on IDO2    1. functional importance of IDO enzymes in human Crohn's disease
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IDO2 antibodyDiseases associated with anti-IDO2 antibody
 Reference Product  PubMed Publications
 TPH1 antibody  >1 publications with IDO2 and TPH1
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with IDO2 and Inflammation
 Disease Models, Animal Antibodies  >5 publications with IDO2 and Disease Models, Animal
 Mental Disorders Antibodies  >3 publications with IDO2 and Mental Disorders
 Lung Diseases Antibodies  >2 publications with IDO2 and Lung Diseases
 Necrosis Antibodies  >2 publications with IDO2 and Necrosis
 Cognition Disorders Antibodies  >2 publications with IDO2 and Cognition Disorders
 Vascular Diseases Antibodies  >1 publications with IDO2 and Vascular Diseases
 Immunoproliferative Disorders Antibodies  >1 publications with IDO2 and Immunoproliferative Disorders
 Depressive Disorder Antibodies  >1 publications with IDO2 and Depressive Disorder
 Weight Loss Antibodies  >1 publications with IDO2 and Weight Loss
Organs/Tissues associated with anti-IDO2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with IDO2 and Brain
 Liver Antibodies  >3 publications with IDO2 and Liver
 Mixed Antibodies  >2 publications with IDO2 and Mixed
 Uterus Antibodies  >1 publications with IDO2 and Uterus
 Placenta Antibodies  >1 publications with IDO2 and Placenta
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