View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-IGFBP3 antibody :: anti-Human Insulin Like Growth Factor Binding Protein 3 (IGFBP3) Polyclonal Antibody Catalog # MBS2014524 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody Full Product Name FITC-linked Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3) Product Gene Name anti-IGFBP3 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Chromosome Location Chromosome: 4; AC_000161.1 (76705105..76713511). Location: chromosome: 4 3D Structure ModBase 3D Structure for P20959 Clonality Polyclonal Species Reactivity Human Concentration 200ug/ml (lot specific) Preparation and Storage Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles. ISO Certification Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory. Supply Chain Verification Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire. Other Notes Small volumes of anti-IGFBP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Product Categories/Family for anti-IGFBP3 antibody FITC Antibody Applications Tested/Suitable for anti-IGFBP3 antibody Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB) TOP NCBI/Uniprot data below describe general gene information for IGFBP3. It may not necessarily be applicable to this product. NCBI GI # 27807007 NCBI GeneID 282261 NCBI Accession # NP_776981.1 [Other Products] NCBI GenBank Nucleotide # NM_174556.1 [Other Products] UniProt Primary Accession # P20959 [Other Products] UniProt Secondary Accession # Q9GJV5; A6QPI3[Other Products] UniProt Related Accession # P20959[Other Products] Molecular Weight 31,570 Da TOP NCBI Official Full Name insulin-like growth factor-binding protein 3 NCBI Official Synonym Full Names insulin-like growth factor binding protein 3< NCBI Official Symbol IGFBP3 [Similar Products] NCBI Official Synonym Symbols IGFBP-3 [Similar Products] NCBI Protein Information insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; insulin-like growth factor binding protein-3 UniProt Protein Name Insulin-like growth factor-binding protein 3 Protein Family Insulin-like growth factor-binding protein UniProt Gene Name IGFBP3 [Similar Products] UniProt Synonym Gene Names IBP-3; IGF-binding protein 3; IGFBP-3 [Similar Products] UniProt Entry Name IBP3_BOVIN TOP TOP UniProt Comments for IGFBP3 Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.Subunit structure: Interacts with HN. Interacts with TMEM219 By similarity. Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with XLKD1. Ref.6Subcellular location: Secreted. Tissue specificity: Plasma; expressed by most tissues.Post-translational modification: Phosphorylation sites are present in the extracellular medium By similarity.Sequence similarities: Contains 1 IGFBP N-terminal domain.Contains 1 thyroglobulin type-1 domain. Research Articles on IGFBP3 1. The present study suggests that the insulin like growth factor (IGF) system or imbalances between IGF and IGF binding proteins may be involved in cystic ovary disease of cattle. 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TOP Products associated with anti-IGFBP3 antibody Reference Product PubMed Publications IGF1 antibody >190 publications with IGFBP3 and IGF1 IGF2 antibody >68 publications with IGFBP3 and IGF2 IGFALS antibody >18 publications with IGFBP3 and IGFALS PRL antibody >18 publications with IGFBP3 and PRL TP53 antibody >11 publications with IGFBP3 and TP53 INS antibody >6 publications with IGFBP3 and INS BMP4 antibody >5 publications with IGFBP3 and BMP4 FN1 antibody >1 publications with IGFBP3 and FN1 Pathways associated with anti-IGFBP3 antibody Products by Pathway Pathway Diagram Metabolism Of Proteins Pathway antibodies Metabolism Of Proteins Pathway Diagram Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram Transcriptional Misregulation In Cancer Pathway antibodies Transcriptional Misregulation In Cancer Pathway Diagram Transcriptional Misregulation In Cancer Pathway antibodies Transcriptional Misregulation In Cancer Pathway Diagram P53 Signaling Pathway antibodies P53 Signaling Pathway Diagram P53 Signaling Pathway antibodies P53 Signaling Pathway Diagram Diseases associated with anti-IGFBP3 antibody Disease Name Pubmed Publications Neoplasms Antibodies >1218 publications with IGFBP3 and Neoplasms Breast Neoplasms Antibodies >331 publications with IGFBP3 and Breast Neoplasms Prostatic Neoplasms Antibodies >251 publications with IGFBP3 and Prostatic Neoplasms Cardiovascular Diseases Antibodies >211 publications with IGFBP3 and Cardiovascular Diseases Adenocarcinoma Antibodies >165 publications with IGFBP3 and Adenocarcinoma Colorectal Neoplasms Antibodies >140 publications with IGFBP3 and Colorectal Neoplasms Liver Diseases Antibodies >138 publications with IGFBP3 and Liver Diseases Kidney Diseases Antibodies >120 publications with IGFBP3 and Kidney Diseases Inflammation Antibodies >119 publications with IGFBP3 and Inflammation Necrosis Antibodies >106 publications with IGFBP3 and Necrosis Organs/Tissues associated with anti-IGFBP3 antibody Organ/Tissue Name Pubmed Publications Liver Antibodies >404 publications with IGFBP3 and Liver Muscle Antibodies >285 publications with IGFBP3 and Muscle Kidney Antibodies >201 publications with IGFBP3 and Kidney Brain Antibodies >194 publications with IGFBP3 and Brain Lung Antibodies >172 publications with IGFBP3 and Lung Ovary Antibodies >157 publications with IGFBP3 and Ovary Skin Antibodies >107 publications with IGFBP3 and Skin Uterus Antibodies >71 publications with IGFBP3 and Uterus Pituitary Gland Antibodies >68 publications with IGFBP3 and Pituitary Gland Intestine Antibodies >65 publications with IGFBP3 and Intestine TOP © 2006-24 MyBioSource.com. 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