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anti-ITGaX antibody :: Rabbit Integrin Alpha X Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2027186 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Integrin Alpha X (ITGaX), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Integrin Alpha X (ITGaX)

 Product Gene Name   

anti-ITGaX antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2027186 Technical Datasheet    Technical Datasheet PDF
 3D Structure    ModBase 3D Structure for Q9QXH4
 Clonality    Polyclonal
 Host    Rabbit
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 Purity/Purification    Antigen-specific affinity chromatography followed by Protein A affinity chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    0.35 mg/ml (lot specific)
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 Organism Species    Mus musculus
 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant CD11c (Arg907~Val1115) expressed in E.coli
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-ITGaX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ITGaX antibody   

WB; IHC; ICC; IP.

 Application Notes for anti-ITGaX antibody    Western blotting: 0.5-2) Ug/mL;1:170-700
Immunohistochemistry: 5-20) Ug/mL;1:17-70
Immunocytochemistry: 5-20) Ug/mL;1:17-70

Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-ITGaX antibody    (Figure. Western Blot; Sample: Recombinant ITGaX, Mouse.)
anti-ITGaX antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ITGaX antibody    (Used in DAB staining on formalin fixed paraffin- embedded Kidney tissue)
anti-ITGaX antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ITGaX. It may not necessarily be applicable to this product.
 NCBI GI #    10946646
 NCBI GeneID    16411
 NCBI Accession #    NP_067309.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021334.2 [Other Products]
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 UniProt Primary Accession #    Q9QXH4 [Other Products]
 UniProt Related Accession #    Q9QXH4 [Other Products]
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 NCBI Official Full Name    integrin alpha-X
 NCBI Official Synonym Full Names    integrin alpha X
 NCBI Official Symbol    Itgax [Similar Products]
 NCBI Official Synonym Symbols   
Cr4; N418; Cd11c; AI449405
[Similar Products]
 NCBI Protein Information    integrin alpha-X
 UniProt Protein Name    Integrin alpha-X
 UniProt Synonym Protein Names   
CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c
 Protein Family    Integrin
 UniProt Gene Name    Itgax [Similar Products]
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 UniProt Comments for ITGaX    ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7|7 F3

Cellular Component: cell surface; external side of plasma membrane; integral component of membrane; integrin complex; membrane

Molecular Function: metal ion binding

Biological Process: activated T cell proliferation; cell adhesion; defense response to virus; heterotypic cell-cell adhesion; integrin-mediated signaling pathway
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 Research Articles on ITGaX    1. MyD88 signaling in lysozyme M and CD11c-expressing myeloid cells, as well as in pulmonary epithelial cells, is critical to restore inflammatory cytokine and antimicrobial peptide production, leading to efficient neutrophil recruitment and enhanced bacterial clearance.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ITGaX antibodyDiseases associated with anti-ITGaX antibody
 Products by Pathway  Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Integrin-mediated Cell Adhesion Pathway antibodies  Integrin-mediated Cell Adhesion Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >526 publications with ITGaX and Inflammation
 Necrosis Antibodies  >358 publications with ITGaX and Necrosis
 Disease Models, Animal Antibodies  >298 publications with ITGaX and Disease Models, Animal
 Lung Diseases Antibodies  >167 publications with ITGaX and Lung Diseases
 Nervous System Diseases Antibodies  >119 publications with ITGaX and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >110 publications with ITGaX and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >108 publications with ITGaX and Cardiovascular Diseases
 Asthma Antibodies  >70 publications with ITGaX and Asthma
 Liver Diseases Antibodies  >60 publications with ITGaX and Liver Diseases
 Atherosclerosis Antibodies  >50 publications with ITGaX and Atherosclerosis
Organs/Tissues associated with anti-ITGaX antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2180 publications with ITGaX and Blood
 Bone Antibodies  >569 publications with ITGaX and Bone
 Bone Marrow Antibodies  >549 publications with ITGaX and Bone Marrow
 Spleen Antibodies  >445 publications with ITGaX and Spleen
 Lymph Node Antibodies  >412 publications with ITGaX and Lymph Node
 Lung Antibodies  >293 publications with ITGaX and Lung
 Skin Antibodies  >245 publications with ITGaX and Skin
 Intestine Antibodies  >142 publications with ITGaX and Intestine
 Thymus Antibodies  >77 publications with ITGaX and Thymus
 Joint Antibodies  >29 publications with ITGaX and Joint
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