P24063.2
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
128,328 Da
NCBI Official Full Name
Integrin alpha-L
NCBI Official Synonym Full Names
integrin alpha L
NCBI Official Synonym Symbols
Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A [Similar Products]
NCBI Protein Information
integrin alpha-L
UniProt Protein Name
Integrin alpha-L
UniProt Synonym Protein Names
CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; Lymphocyte antigen 15; Ly-15; CD_antigen: CD11a
UniProt Synonym Gene Names
UniProt Entry Name
ITAL_MOUSE
UniProt Comments for Itgal
ITGAL: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Belongs to the integrin alpha chain family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis; Cell surface
Cellular Component: cell surface; external side of plasma membrane; immunological synapse; integral to membrane; integrin complex; intercellular junction; membrane
Molecular Function: cell adhesion molecule binding; ICAM-3 receptor activity; metal ion binding; protein complex binding; protein heterodimerization activity
Biological Process: activated T cell proliferation; cell adhesion; cell surface receptor linked signal transduction; cell-cell adhesion; cell-matrix adhesion; heterophilic cell adhesion; integrin-mediated signaling pathway; leukocyte adhesion; positive regulation of calcium-mediated signaling; positive regulation of cell-cell adhesion; positive regulation of T cell proliferation; receptor clustering; regulation of cell-cell adhesion; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
Research Articles on Itgal
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Products associated with anti-Itgal antibody
Pathways associated with anti-Itgal antibody
Organs/Tissues associated with anti-Itgal antibody
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