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anti-ITGA9 antibody :: Goat anti-Human, Mouse Integrin, alpha9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS611310 anti-ITGA9 antibody
Unit / Price
0.1 mg  /  $765 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Integrin, alpha9 (ITGA9), Polyclonal Antibody

 Also Known As   

Integrin, alpha9 (Integrin alpha4-like)

 Product Synonym Names    Anti -Integrin, alpha9 (Integrin alpha4-like)
 Product Gene Name   

anti-ITGA9 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 3; NC_000003.11 (37493813..37861281). Location: 3p21.3
 OMIM    603963
 3D Structure    ModBase 3D Structure for Q13797
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Goat
 Species Reactivity    Human, Mouse
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 Specificity    Recognizes mouse Integrin alpha9. Shows <5% crossreactivity with recombinant human Integrin alpha1, alpha8, alpha9, alphaL, recombinant mouse Integrin 3, 4, 5, E and M.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 500ul sterile PBS.
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 Immunogen    Recombinant protein corresponding to Try31-Val979 from mouse Integin alpha9 expressed in NSO cells (NP_598482).
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
 Other Notes    Small volumes of anti-ITGA9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ITGA9 antibody

   Integrin alpha9 is a 150kD type I transmembrane glycoprotein that is widely expressed and is found on smooth muscle, keratinocytes, skeletal muscle and hepatocytes. It principally associates with the beta1 integrin. Alpha9beta1 binds to VEGF-C and D, and osteopontin. The 951 amino acid (aa) extracellular domain of mouse integrin alpha9 contains three beta-propellor repeats and multiple PheGly-GlyAlaPro repeats. A potential proteolytic cleavage site in human alpha9 ECD is absolutely conserved in mouse alpha9 ECD (Arg 566-Val 567). The ECD of mouse integrin alpha9 shares 95% and 89% aa sequence identity to rat and human integrin alpha9, respectively.
 Product Categories/Family for anti-ITGA9 antibody    Antibodies; Abs to Integrin
 Applications Tested/Suitable for anti-ITGA9 antibody   

ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)

 Application Notes for anti-ITGA9 antibody    Suitable for use in Western Blot, Flow Cytometry and ELISA.
Dilution: Western Blot: 0.1ug/ml. Tested on recombinant mouse Integrin alpha9.
Flow Cytometry: 2.5ug labels 10e6 cells. Tested on D3 mouse embryonic stem cells.
Optimal dilutions should be determined by each laboratory for each application.
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NCBI/Uniprot data below describe general gene information for ITGA9. It may not necessarily be applicable to this product.
 NCBI GI #    52485941
 NCBI GeneID    3680
 NCBI Accession #    NP_002198.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002207.2 [Other Products]
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 UniProt Primary Accession #    Q13797 [Other Products]
 UniProt Secondary Accession #    Q14638 [Other Products]
 UniProt Related Accession #    Q13797; Q8N6H6 [Other Products]
 Molecular Weight    114,489 Da [Similar Products]
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 NCBI Official Full Name    integrin alpha-9
 NCBI Official Synonym Full Names    integrin, alpha 9
 NCBI Official Symbol    ITGA9 [Similar Products]
 NCBI Official Synonym Symbols   
RLC; ITGA4L; ALPHA-RLC
[Similar Products]
 NCBI Protein Information    integrin alpha-9; OTTHUMP00000161385; integrin alpha-RLC
 UniProt Protein Name    Integrin alpha-9
 UniProt Synonym Protein Names   
Integrin alpha-RLC
 Protein Family    Integrin
 UniProt Gene Name    ITGA9 [Similar Products]
 UniProt Entry Name    ITA9_HUMAN
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 NCBI Summary for ITGA9    This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq]
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 UniProt Comments for ITGA9    ITGA9: Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin. Belongs to the integrin alpha chain family.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: plasma membrane; basal plasma membrane; integrin complex

Molecular Function: collagen binding; metal ion binding; laminin binding

Biological Process: integrin-mediated signaling pathway; axon guidance; neutrophil chemotaxis; extracellular matrix organization and biogenesis; wound healing; cell adhesion
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 Research Articles on ITGA9    1. the three-amino acid sequence, EYP, encoded by exon 3 of VEGF-A is essential for binding of VEGF to integrin alpha9beta1 and induces adhesion and migration of endothelial and cancer cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ITGA9 antibodyPathways associated with anti-ITGA9 antibody
 Reference Product  PubMed Publications
 ITGB1 antibody  >3 publications with ITGA9 and ITGB1
 Products by Pathway  Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with anti-ITGA9 antibodyOrgans/Tissues associated with anti-ITGA9 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >12 publications with ITGA9 and Neoplasms
 Breast Neoplasms Antibodies  >4 publications with ITGA9 and Breast Neoplasms
 Lung Neoplasms Antibodies  >4 publications with ITGA9 and Lung Neoplasms
 Female Urogenital Diseases Antibodies  >3 publications with ITGA9 and Female Urogenital Diseases
 Colorectal Neoplasms Antibodies  >3 publications with ITGA9 and Colorectal Neoplasms
 Adenocarcinoma Antibodies  >3 publications with ITGA9 and Adenocarcinoma
 Carcinoma, Non-Small-Cell Lung Antibodies  >2 publications with ITGA9 and Carcinoma, Non-Small-Cell Lung
 Kidney Neoplasms Antibodies  >2 publications with ITGA9 and Kidney Neoplasms
 Head and Neck Neoplasms Antibodies  >2 publications with ITGA9 and Head and Neck Neoplasms
 Uterine Cervical Neoplasms Antibodies  >2 publications with ITGA9 and Uterine Cervical Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with ITGA9 and Lung
 Kidney Antibodies  >2 publications with ITGA9 and Kidney
 Blood Antibodies  >2 publications with ITGA9 and Blood
 Lymph Node Antibodies  >2 publications with ITGA9 and Lymph Node
 Prostate Antibodies  >1 publications with ITGA9 and Prostate
 Muscle Antibodies  >1 publications with ITGA9 and Muscle
 Ovary Antibodies  >1 publications with ITGA9 and Ovary
 Liver Antibodies  >1 publications with ITGA9 and Liver
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