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anti-IFNg antibody :: anti-Guinea Pig Interferon Gamma (IFNg) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2013513 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-IFNg antibody
Unit / Price
0.1 mg  /  $250 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interferon Gamma (IFNg), Polyclonal Antibody

★Popular Item★
 Also Known As   

Biotin-Linked Antibody to Interferon Gamma (IFNg)

 Product Gene Name   

anti-IFNg antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 12; NC_000012.11 (68548550..68553521, complement). Location: 12q14
 OMIM    147570
 3D Structure    ModBase 3D Structure for P01579
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 Clonality    Polyclonal
 Species Reactivity    Guinea Pig
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 Concentration    200ug/ml (lot specific)
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-IFNg antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-IFNg antibody    Biotin Antibody
 Applications Tested/Suitable for anti-IFNg antibody   

Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for IFNg. It may not necessarily be applicable to this product.
 NCBI GI #    56786138
 NCBI GeneID    3458
 NCBI Accession #    NP_000610.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000619.2 [Other Products]
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 UniProt Primary Accession #    P01579 [Other Products]
 UniProt Secondary Accession #    Q53ZV4; B5BU88 [Other Products]
 UniProt Related Accession #    P01579 [Other Products]
 Molecular Weight    19,348 Da
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 NCBI Official Full Name    interferon gamma
 NCBI Official Synonym Full Names    interferon, gamma
 NCBI Official Symbol    IFNG [Similar Products]
 NCBI Official Synonym Symbols   
IFG; IFI
[Similar Products]
 NCBI Protein Information    interferon gamma; IFN-gamma; immune interferon
 UniProt Protein Name    Interferon gamma
 UniProt Synonym Protein Names   
Immune interferon
 Protein Family    Interferon
 UniProt Gene Name    IFNG [Similar Products]
 UniProt Synonym Gene Names    IFN-gamma [Similar Products]
 UniProt Entry Name    IFNG_HUMAN
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 NCBI Summary for IFNg    This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015]
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 UniProt Comments for IFNg    IFNG: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Homodimer. Released primarily from activated T lymphocytes. Belongs to the type II (or gamma) interferon family.

Protein type: Membrane protein, integral; Secreted, signal peptide; Cytokine; Secreted

Chromosomal Location of Human Ortholog: 12q14

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: interferon-gamma receptor binding; cytokine activity

Biological Process: positive regulation of isotype switching to IgG isotypes; positive regulation of nitric oxide biosynthetic process; positive regulation of interleukin-23 production; negative regulation of smooth muscle cell proliferation; apoptosis; positive regulation of osteoclast differentiation; positive regulation of interleukin-12 production; positive regulation of interleukin-6 biosynthetic process; negative regulation of epithelial cell differentiation; positive regulation of interleukin-1 beta secretion; sensory perception of mechanical stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of killing of cells of another organism; positive regulation of membrane protein ectodomain proteolysis; cell surface receptor linked signal transduction; positive regulation of MHC class II biosynthetic process; positive regulation of cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of T cell proliferation; cell cycle arrest; defense response to virus; regulation of the force of heart contraction; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to drug; neutrophil chemotaxis; positive regulation of synaptic transmission, cholinergic; adaptive immune response; CD8-positive, alpha-beta T cell differentiation during immune response; negative regulation of myelination; unfolded protein response; cytokine and chemokine mediated signaling pathway; response to virus; positive regulation of tumor necrosis factor production; defense response to protozoan; humoral immune response; antigen processing and presentation; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of interleukin-12 biosynthetic process; negative regulation of interleukin-17 production; positive regulation of chemokine biosynthetic process; protein import into nucleus, translocation; defense response to bacterium; neutrophil apoptosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation; cell motility; regulation of insulin secretion

Disease: Hepatitis C Virus, Susceptibility To; Aplastic Anemia; Mycobacterium Tuberculosis, Susceptibility To; Tuberous Sclerosis 2; Human Immunodeficiency Virus Type 1, Susceptibility To
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 Research Articles on IFNg    1. suggest that the interferon gamma gene may be a susceptibility gene and a risk factor for hepatocellular carcinoma in the Korean population
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IFNg antibodyPathways associated with anti-IFNg antibody
 Reference Product  PubMed Publications
 CD4 antibody  >124 publications with IFNg and CD4
 TBX21 antibody  >46 publications with IFNg and TBX21
 IL2 antibody  >42 publications with IFNg and IL2
 STAT1 antibody  >31 publications with IFNg and STAT1
 IFNGR1 antibody  >24 publications with IFNg and IFNGR1
 IL18 antibody  >21 publications with IFNg and IL18
 IRF1 antibody  >16 publications with IFNg and IRF1
 CD86 antibody  >3 publications with IFNg and CD86
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
Diseases associated with anti-IFNg antibodyOrgans/Tissues associated with anti-IFNg antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >110 publications with IFNg and Necrosis
 Autoimmune Diseases Antibodies  >72 publications with IFNg and Autoimmune Diseases
 Respiratory Tract Diseases Antibodies  >55 publications with IFNg and Respiratory Tract Diseases
 Hepatitis Antibodies  >26 publications with IFNg and Hepatitis
 MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO Antibodies  >21 publications with IFNg and MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO
 Lymphoproliferative Disorders Antibodies  >17 publications with IFNg and Lymphoproliferative Disorders
 Diabetes Mellitus, Type 1 Antibodies  >15 publications with IFNg and Diabetes Mellitus, Type 1
 HIV Infections Antibodies  >13 publications with IFNg and HIV Infections
 Hepatitis C Antibodies  >11 publications with IFNg and Hepatitis C
 Arthritis, Rheumatoid Antibodies  >10 publications with IFNg and Arthritis, Rheumatoid
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >366 publications with IFNg and Blood
 Kidney Antibodies  >32 publications with IFNg and Kidney
 Lymph Node Antibodies  >22 publications with IFNg and Lymph Node
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