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anti-IL15 antibody :: Rabbit anti-Human Interleukin 15 (IL15) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2004677 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $90 +1 FREE 8GB USB
0.02 mg  /  $105 +1 FREE 8GB USB
0.05 mg  /  $135 +1 FREE 8GB USB
0.1 mg  /  $165 +1 FREE 8GB USB
0.2 mg  /  $230 +1 FREE 8GB USB
1 mg  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 15 (IL15), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Interleukin 15 (IL15)

 Product Gene Name   

anti-IL15 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    U14407 mRNA
 3D Structure    ModBase 3D Structure for P40933
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is aRabbit polyclonalantibody raised againstIL15. It has been selected for its ability to recognizeIL15 in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
 Concentration    200g/mL (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant IL15 (Trp50~Ser162) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2036436
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-IL15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL15 antibody   

WB; IHC; ICC; IP

 Application Notes for anti-IL15 antibody    Western blotting: 0.5-2g/mL
Immunohistochemistry: 5-20g/mL
Immunocytochemistry: 5-20g/mL

Optimal working dilutions must be determined by end user
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 Western Blot (WB) of anti-IL15 antibody    (Figure. Western Blot; Sample: Recombinant IL15, Human.)
anti-IL15 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-IL15 antibody    (Figure. DAB staining on IHC-P; Samples: Human Kidney Tissue.)
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IL15 antibody    (Figure. DAB staining on IHC-P; Samples: Human Stomach Tissue.)
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IL15 antibody    (Figure. DAB staining on IHC-P; Samples: Human Pancreas Cancer Tissue.)
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IL15 antibody    (Figure. DAB staining on IHC-P; Samples: Human Liver Cancer Tissue.)
anti-IL15 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for IL15. It may not necessarily be applicable to this product.
 NCBI GI #    10835153
 NCBI GeneID    3600
 NCBI Accession #    NP_000576.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000585.4 [Other Products]
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 UniProt Primary Accession #    P40933 [Other Products]
 UniProt Secondary Accession #    O00440; O43512; Q495Z8; Q6FGX7; Q93058; Q9UBA3; D3DNZ2 [Other Products]
 UniProt Related Accession #    P40933 [Other Products]
 Molecular Weight    14,912 Da
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 NCBI Official Full Name    interleukin-15 isoform 1 preproprotein
 NCBI Official Synonym Full Names    interleukin 15
 NCBI Official Symbol    IL15 [Similar Products]
 NCBI Official Synonym Symbols   
IL-15
[Similar Products]
 NCBI Protein Information    interleukin-15
 UniProt Protein Name    Interleukin-15
 Protein Family    Interleukin
 UniProt Gene Name    IL15 [Similar Products]
 UniProt Synonym Gene Names    IL-15 [Similar Products]
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 NCBI Summary for IL15    The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
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 UniProt Comments for IL15    IL15: Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. Belongs to the IL-15/IL-21 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q31.21

Cellular Component: cell surface; cytoplasm; cytosol; endosome; extracellular region; extracellular space; Golgi apparatus; integral component of plasma membrane; membrane; nuclear speck; nucleoplasm

Molecular Function: cytokine activity; cytokine receptor binding; protein binding

Biological Process: aging; cell maturation; cell-cell signaling; extrathymic T cell selection; hyaluronan metabolic process; immune response; inflammatory response; lymph node development; natural killer cell differentiation; negative regulation of smooth muscle cell proliferation; NK T cell proliferation; positive regulation of cell proliferation; positive regulation of immune response; positive regulation of inflammatory response; positive regulation of interleukin-17 production; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell proliferation; positive regulation of T cell proliferation; positive regulation of tissue remodeling; positive regulation of tyrosine phosphorylation of STAT protein; regulation of defense response to virus by host; regulation of T cell differentiation; signal transduction; skeletal muscle atrophy; tyrosine phosphorylation of STAT protein
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 Research Articles on IL15    1. the critical role played by IL-7 and IL-15 in T cell homeostasis and how these cytokines could be used to improve immune reconstitution after allogeneic SCT.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL15 antibodyPathways associated with anti-IL15 antibody
 Reference Product  PubMed Publications
 IL15RA antibody  >227 publications with IL15 and IL15RA
 PRF1 antibody  >101 publications with IL15 and PRF1
 IL2RA antibody  >100 publications with IL15 and IL2RA
 IL2RB antibody  >81 publications with IL15 and IL2RB
 IL2RG antibody  >70 publications with IL15 and IL2RG
 IL7 antibody  >31 publications with IL15 and IL7
 IL4 antibody  >20 publications with IL15 and IL4
 IFNG antibody  >8 publications with IL15 and IFNG
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with anti-IL15 antibodyOrgans/Tissues associated with anti-IL15 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >449 publications with IL15 and Neoplasms
 Necrosis Antibodies  >318 publications with IL15 and Necrosis
 Inflammation Antibodies  >303 publications with IL15 and Inflammation
 Disease Models, Animal Antibodies  >150 publications with IL15 and Disease Models, Animal
 Death Antibodies  >130 publications with IL15 and Death
 Nervous System Diseases Antibodies  >93 publications with IL15 and Nervous System Diseases
 Lung Diseases Antibodies  >90 publications with IL15 and Lung Diseases
 Neoplasms, Experimental Antibodies  >88 publications with IL15 and Neoplasms, Experimental
 Hematologic Diseases Antibodies  >80 publications with IL15 and Hematologic Diseases
 Liver Diseases Antibodies  >51 publications with IL15 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >40 publications with IL15 and Mixed
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