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anti-IL18 antibody :: Rabbit anti-Mouse Interleukin 18 (IL18) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2006788 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $210 +1 FREE 8GB USB
0.2 mg  /  $315 +1 FREE 8GB USB
1 mg  /  $745 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 18 (IL18), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Interleukin 18 (IL18)

 Product Gene Name   

anti-IL18 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
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 Matching Pairs    Antibody: Interleukin 18 (IL18) (MBS2006788)
Antigen: Interleukin 18 (IL18) (MBS2009981)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
APC-CY7 Conjugated Antibody: Interleukin 18 (IL18) (MBS2036569)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
PE Conjugated Antibody: Interleukin 18 (IL18) (MBS2036570)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
APC-CY7 Conjugated Antibody: Interleukin 18 (IL18) (MBS2036571)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
Cy3 Conjugated Antibody: Interleukin 18 (IL18) (MBS2036572)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
FITC Conjugated Antibody: Interleukin 18 (IL18) (MBS2036573)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
HRP Conjugated Antibody: Interleukin 18 (IL18) (MBS2036574)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Interleukin 18 (IL18) (MBS2006788)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with a His-tag and its sequence is listed below.
MGHHHHHHSG SEF-NFGRL HCTTAVIRNI NDQVLFVDKR QPVFEDMTDI DQSASEPQTR LIIYMYKDSE VRGLAVTLSV KDSKMSTLSC KNKIISFEEM DPPENIDDIQ SDLIFFQKRV PGHNKMEFES SLYEGHFLAC QKEDDAFKLI LKKKDENGDK SVMFTLTNLH QS
 3D Structure    ModBase 3D Structure for P70380
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a rabbit polyclonal antibody raised against IL18. It has been selected for its ability to recognize IL18 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant IL18 (Asn36~Ser192) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2036571
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-IL18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL18 antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-IL18 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-IL18 antibody    (Figure. Western Blot; Sample: Recombinant IL18, Mouse.)
anti-IL18 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-IL18 antibody    (Used in DAB staining on formalin fixed paraffin-embedded Lung tissue)
anti-IL18 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for IL18. It may not necessarily be applicable to this product.
 NCBI GI #    6680413
 NCBI GeneID    16173
 NCBI Accession #    NP_032386.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008360.2 [Other Products]
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 UniProt Primary Accession #    P70380 [Other Products]
 UniProt Related Accession #    P70380 [Other Products]
 Molecular Weight    22,135 Da
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 NCBI Official Full Name    interleukin-18 isoform a
 NCBI Official Synonym Full Names    interleukin 18
 NCBI Official Symbol    Il18 [Similar Products]
 NCBI Official Synonym Symbols   
Igif; Il-18
[Similar Products]
 NCBI Protein Information    interleukin-18
 UniProt Protein Name    Interleukin-18
 UniProt Synonym Protein Names   
Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
 Protein Family    Interleukin
 UniProt Gene Name    Il18 [Similar Products]
 UniProt Synonym Gene Names    Igif; IL-18; IFN-gamma-inducing factor; IL-1 gamma [Similar Products]
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 UniProt Comments for IL18    IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 9 A5.3|9 27.75 cM

Cellular Component: apical plasma membrane; cytoplasm; extracellular region; extracellular space

Molecular Function: cytokine activity

Biological Process: activation of protein kinase B activity; angiogenesis; cell proliferation; cholesterol homeostasis; detection of mechanical stimulus involved in sensory perception of pain; immune response; induction of apoptosis via death domain receptors; inflammatory response; interferon-gamma biosynthetic process; interferon-gamma production; interleukin-13 biosynthetic process; interleukin-6 production; lipopolysaccharide-mediated signaling pathway; MAPK cascade; natural killer cell activation; natural killer cell mediated cytotoxicity; negative regulation of myoblast differentiation; negative regulation of neutrophil apoptosis; negative regulation of peptidyl-tyrosine phosphorylation; neutrophil activation; positive regulation of activated T cell proliferation; positive regulation of apoptosis; positive regulation of chemokine production; positive regulation of collagen biosynthetic process; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of interferon-gamma production; positive regulation of interleukin-17 production; positive regulation of interleukin-8 production; positive regulation of natural killer cell proliferation; positive regulation of neuron apoptotic process; positive regulation of NF-kappaB import into nucleus; positive regulation of NK T cell proliferation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of superoxide anion generation; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; positive regulation of tyrosine phosphorylation of STAT protein; positive regulation of vascular permeability; regulation of cell adhesion; response to hypoxia; sleep; T-helper 1 type immune response
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 Research Articles on IL18    1. MyD88 signaling in myeloid and dendritic cells is dispensable for IFN-gamma-dependent control of type A F. tularensis infection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL18 antibodyPathways associated with anti-IL18 antibody
 Reference Product  PubMed Publications
 Casp1 antibody  >658 publications with IL18 and Casp1
 Il18r1 antibody  >235 publications with IL18 and Il18r1
 Il1b antibody  >89 publications with IL18 and Il1b
 Il18rap antibody  >44 publications with IL18 and Il18rap
 Cd69 antibody  >28 publications with IL18 and Cd69
 Stat3 antibody  >25 publications with IL18 and Stat3
 Il18bp antibody  >21 publications with IL18 and Il18bp
 Rela antibody  >13 publications with IL18 and Rela
 Nfkb1 antibody  >6 publications with IL18 and Nfkb1
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
Diseases associated with anti-IL18 antibodyOrgans/Tissues associated with anti-IL18 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1395 publications with IL18 and Inflammation
 Necrosis Antibodies  >869 publications with IL18 and Necrosis
 Cardiovascular Diseases Antibodies  >501 publications with IL18 and Cardiovascular Diseases
 Lung Diseases Antibodies  >368 publications with IL18 and Lung Diseases
 Kidney Diseases Antibodies  >366 publications with IL18 and Kidney Diseases
 Hypersensitivity Antibodies  >293 publications with IL18 and Hypersensitivity
 Heart Diseases Antibodies  >242 publications with IL18 and Heart Diseases
 Arthritis, Rheumatoid Antibodies  >234 publications with IL18 and Arthritis, Rheumatoid
 Hypersensitivity, Immediate Antibodies  >207 publications with IL18 and Hypersensitivity, Immediate
 Atherosclerosis Antibodies  >175 publications with IL18 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >456 publications with IL18 and Liver
 Spleen Antibodies  >297 publications with IL18 and Spleen
 Brain Antibodies  >247 publications with IL18 and Brain
 Skin Antibodies  >239 publications with IL18 and Skin
 Intestine Antibodies  >192 publications with IL18 and Intestine
 Eye Antibodies  >54 publications with IL18 and Eye
 Stomach Antibodies  >43 publications with IL18 and Stomach
 Embryonic Tissue Antibodies  >39 publications with IL18 and Embryonic Tissue
 Thymus Antibodies  >30 publications with IL18 and Thymus
 Ovary Antibodies  >29 publications with IL18 and Ovary
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