NP_001152896.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
24,179 Da
NCBI Official Full Name
interleukin-12 subunit alpha isoform 1
NCBI Official Synonym Full Names
interleukin 12a
NCBI Protein Information
interleukin-12 subunit alpha
UniProt Protein Name
Interleukin-12 subunit alpha
UniProt Synonym Protein Names
Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35
UniProt Synonym Gene Names
UniProt Comments for IL35
IL12A: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-6 superfamily.
Protein type: Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3 E1|3 31.92 cM
Cellular Component: cytoplasm; extracellular region; extracellular space; interleukin-12 complex
Molecular Function: cytokine activity; growth factor activity; interleukin-12 beta subunit binding; interleukin-12 receptor binding; interleukin-27 binding; protein heterodimerization activity
Biological Process: cell cycle arrest; cell migration; cell proliferation; defense response to protozoan; immune response; interferon-gamma production; negative regulation of interleukin-17 production; negative regulation of smooth muscle cell proliferation; positive regulation of cell adhesion; positive regulation of interferon-gamma production; positive regulation of lymphocyte proliferation; positive regulation of mononuclear cell proliferation; positive regulation of natural killer cell activation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of NK T cell activation; positive regulation of T cell differentiation; positive regulation of T cell mediated cytotoxicity; positive regulation of T cell proliferation; positive regulation of tyrosine phosphorylation of STAT protein; response to lipopolysaccharide; response to UV-B
Research Articles on IL35
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Products associated with anti-IL35 antibody
Pathways associated with anti-IL35 antibody
Diseases associated with anti-IL35 antibody
Organs/Tissues associated with anti-IL35 antibody
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