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anti-IL8Rb antibody :: Rabbit anti-Mouse Interleukin 8 Receptor Beta (IL8Rb) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2007271 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-IL8Rb antibody
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $185 +1 FREE 8GB USB
0.1 mg  /  $230 +1 FREE 8GB USB
0.2 mg  /  $345 +1 FREE 8GB USB
1 mg  /  $825 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 8 Receptor Beta (IL8Rb), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb)

 Product Gene Name   

anti-IL8Rb antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P35343
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a rabbit polyclonal antibody raised against IL8Rb. It has been selected for its ability to recognize IL8Rb in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2061937
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-IL8Rb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL8Rb antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-IL8Rb antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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NCBI/Uniprot data below describe general gene information for IL8Rb. It may not necessarily be applicable to this product.
 NCBI GI #    6753456
 NCBI GeneID    12765
 NCBI Accession #    NP_034039.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_009909.3 [Other Products]
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 UniProt Primary Accession #    P35343 [Other Products]
 UniProt Secondary Accession #    Q53X27 [Other Products]
 UniProt Related Accession #    P35343 [Other Products]
 Molecular Weight    40,425 Da
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 NCBI Official Full Name    C-X-C chemokine receptor type 2
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) receptor 2
 NCBI Official Symbol    Cxcr2 [Similar Products]
 NCBI Official Synonym Symbols   
CD128; IL8RA; Il8rb; CDw128; Cmkar2; Gpcr16; IL-8Rh; IL-8rb; mIL-8RH
[Similar Products]
 NCBI Protein Information    C-X-C chemokine receptor type 2
 UniProt Protein Name    C-X-C chemokine receptor type 2
 UniProt Synonym Protein Names   
GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; CD_antigen: CD182
 UniProt Gene Name    Cxcr2 [Similar Products]
 UniProt Synonym Gene Names    Cmkar2; Gpcr16; Il8rb; CXC-R2; CXCR-2; IL-8R B [Similar Products]
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 UniProt Comments for IL8Rb    IL8RB: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; Receptor, cytokine

Chromosomal Location of Human Ortholog: 1 C3|1 38.41 cM

Cellular Component: cell surface; integral component of membrane; intracellular; mast cell granule; membrane; plasma membrane

Molecular Function: C-X-C chemokine receptor activity; chemokine receptor activity; G-protein coupled receptor activity; interleukin-8 binding; interleukin-8 receptor activity; protein binding; signal transducer activity

Biological Process: acute inflammatory response to antigenic stimulus; cell surface receptor signaling pathway; cellular defense response; chemotaxis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; metanephric tubule morphogenesis; negative regulation of apoptosis; negative regulation of neutrophil apoptosis; neutrophil activation; neutrophil chemotaxis; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of angiogenesis; positive regulation of cardiac muscle cell apoptotic process; positive regulation of cell proliferation; positive regulation of leukocyte chemotaxis; positive regulation of neutrophil chemotaxis; positive regulation of vascular permeability; receptor internalization; signal transduction
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 Research Articles on IL8Rb    1. Combining CSF1R inhibitor with a CXCR2 antagonist blocked granulocyte infiltration of tumors and showed strong anti-tumor effects.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL8Rb antibodyPathways associated with anti-IL8Rb antibody
 Reference Product  PubMed Publications
 Cxcl2 antibody  >188 publications with IL8Rb and Cxcl2
 Cxcl5 antibody  >103 publications with IL8Rb and Cxcl5
 Cxcl12 antibody  >75 publications with IL8Rb and Cxcl12
 Cxcl3 antibody  >17 publications with IL8Rb and Cxcl3
 Ppbp antibody  >13 publications with IL8Rb and Ppbp
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
Diseases associated with anti-IL8Rb antibodyOrgans/Tissues associated with anti-IL8Rb antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >578 publications with IL8Rb and Inflammation
 Lung Diseases Antibodies  >211 publications with IL8Rb and Lung Diseases
 Disease Models, Animal Antibodies  >198 publications with IL8Rb and Disease Models, Animal
 Necrosis Antibodies  >147 publications with IL8Rb and Necrosis
 Nervous System Diseases Antibodies  >105 publications with IL8Rb and Nervous System Diseases
 Lung Injury Antibodies  >74 publications with IL8Rb and Lung Injury
 Sepsis Antibodies  >67 publications with IL8Rb and Sepsis
 Hypersensitivity Antibodies  >60 publications with IL8Rb and Hypersensitivity
 Asthma Antibodies  >57 publications with IL8Rb and Asthma
 Liver Diseases Antibodies  >51 publications with IL8Rb and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >148 publications with IL8Rb and Bone
 Spleen Antibodies  >36 publications with IL8Rb and Spleen
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