View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-JAG1 antibody :: Rabbit JAG1 Polyclonal Antibody Catalog # MBS9507602 Unit / Price 0.05 mL / $285 +1 FREE 8GB USB 0.1 mL / $365 +1 FREE 8GB USB 5x0.1 mL / $1,435 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name JAG1, Polyclonal Antibody Full Product Name JAG1 Antibody Product Synonym Names JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339 Product Gene Name anti-JAG1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM AF003837 mRNA 3D Structure ModBase 3D Structure for P78504 Clonality Polyclonal Host Rabbit Species Reactivity Human, Mouse, Rat Specificity JAG1 Antibody detects endogenous levels of JAG1 protein. Purity/Purification Affinity-purified from rabbit antiserum by affinity-chromatography using peptide. Form/Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Concentration 1 mg/ml (lot specific) Target Modification Unmodified/Total Immunogen The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. Immunogen Range 981-1030 Preparation and Storage Stable at -20 degree C for at least 1 year. Other Notes Small volumes of anti-JAG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Applications Tested/Suitable for anti-JAG1 antibody Western Blot (WB), ELISA (EIA) Application Notes for anti-JAG1 antibody WB: 1:500~1:1000ELISA: 1:10000 Western Blot (WB) of anti-JAG1 antibody Western blot analysis of lysate from HeLa cells, using JAG1 Antibody. TOP NCBI/Uniprot data below describe general gene information for JAG1. It may not necessarily be applicable to this product. NCBI GI # 4557679 NCBI GeneID 182 NCBI Accession # NP_000205.1 [Other Products] NCBI GenBank Nucleotide # NM_000214.2 [Other Products] UniProt Primary Accession # P78504 [Other Products] UniProt Secondary Accession # O14902; O15122; Q15816; A0AV43; B4DYR1; E9PCF9[Other Products] UniProt Related Accession # P78504[Other Products] Molecular Weight 133 kDa TOP NCBI Official Full Name protein jagged-1 NCBI Official Synonym Full Names jagged 1 NCBI Official Symbol JAG1 [Similar Products] NCBI Official Synonym Symbols AGS; AHD; AWS; HJ1; AGS1; CD339; JAGL1 [Similar Products] NCBI Protein Information protein jagged-1 UniProt Protein Name Protein jagged-1 UniProt Synonym Protein Names CD_antigen: CD339 Protein Family Protein jagged UniProt Gene Name JAG1 [Similar Products] UniProt Synonym Gene Names JAGL1; Jagged1; hJ1 [Similar Products] TOP NCBI Summary for JAG1 The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008] TOP UniProt Comments for JAG1 Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (). Enhances fibroblast growth factor-induced angiogenesis (in vitro). Research Articles on JAG1 1. Jagged1 (JAG1) thymic medullary niche enriched for dendritic cells (DC)-lineage cells expressing Notch receptors indicate thymus as a DC-poietic organ, which provides selective microenvironments permissive for DC development. 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TOP Products associated with anti-JAG1 antibody Reference Product PubMed Publications NOTCH1 antibody >85 publications with JAG1 and NOTCH1 NOTCH2 antibody >58 publications with JAG1 and NOTCH2 DLL1 antibody >34 publications with JAG1 and DLL1 NOTCH3 antibody >34 publications with JAG1 and NOTCH3 HES5 antibody >19 publications with JAG1 and HES5 ADAM10 antibody >2 publications with JAG1 and ADAM10 MIB1 antibody >2 publications with JAG1 and MIB1 UBC antibody >1 publications with JAG1 and UBC Pathways associated with anti-JAG1 antibody Products by Pathway Pathway Diagram Activated NOTCH1 Transmits Signal To The Nucleus Pathway antibodies Activated NOTCH1 Transmits Signal To The Nucleus Pathway Diagram Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway antibodies Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway Diagram Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway antibodies Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway Diagram Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway antibodies Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway Diagram Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway antibodies Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway Diagram Delta-Notch Signaling Pathway antibodies Delta-Notch Signaling Pathway Diagram Disease Pathway antibodies Disease Pathway Diagram FBXW7 Mutants And NOTCH1 In Cancer Pathway antibodies FBXW7 Mutants And NOTCH1 In Cancer Pathway Diagram NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway antibodies NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway Diagram Notch Signaling Pathway antibodies Notch Signaling Pathway Diagram Diseases associated with anti-JAG1 antibody Disease Name Pubmed Publications Alagille Syndrome Antibodies >125 publications with JAG1 and Alagille Syndrome Liver Diseases Antibodies >108 publications with JAG1 and Liver Diseases Heart Defects, Congenital Antibodies >108 publications with JAG1 and Heart Defects, Congenital Facies Antibodies >31 publications with JAG1 and Facies Heart Diseases Antibodies >29 publications with JAG1 and Heart Diseases Carcinoma Antibodies >28 publications with JAG1 and Carcinoma Breast Neoplasms Antibodies >23 publications with JAG1 and Breast Neoplasms Tetralogy of Fallot Antibodies >17 publications with JAG1 and Tetralogy of Fallot Bone Diseases Antibodies >15 publications with JAG1 and Bone Diseases Eye Abnormalities Antibodies >15 publications with JAG1 and Eye Abnormalities Organs/Tissues associated with anti-JAG1 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >48 publications with JAG1 and Blood Brain Antibodies >30 publications with JAG1 and Brain Embryonic Tissue Antibodies >29 publications with JAG1 and Embryonic Tissue Kidney Antibodies >19 publications with JAG1 and Kidney Lung Antibodies >10 publications with JAG1 and Lung Placenta Antibodies >8 publications with JAG1 and Placenta Pancreas Antibodies >8 publications with JAG1 and Pancreas Connective Tissue Antibodies >7 publications with JAG1 and Connective Tissue Uterus Antibodies >5 publications with JAG1 and Uterus Intestine Antibodies >5 publications with JAG1 and Intestine TOP © 2006-24 MyBioSource.com. 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Privacy Policy | Terms & Conditions 2006 - MySQL server has gone awayselect products_id, products_name, products_gene_name, products_image, clonality, reactivity from products_search_index where products_id IN (1127618, 4662114, 9625746, 3557164, 3168165, 2295559, 8633784, 6656158, 9267827, 3230304, 9899109, 5162924, 9841454, 9747754, 5517040, 634677, 898138, 7442102, 6553839, 3311844, 2642184, 288239, 7109019, 5873483, 3449399, 8747336, 7825511, 2600147, 1343382, 6286773, 758475, 1887278, 2213172, 9724949, 2605187, 1268646, 9404695, 3823968, 7831595, 4601050, 5284080, 7938941, 8405727, 9697695, 4549809, 5629885, 7890888, 9389360, 3783290, 9942977, 4169195, 4805854, 61309, 3900473, 5477788, 5126733, 6852390, 9801004, 4881246, 4616189, 1022033, 9704216, 1121380, 4359502, 8359150, 6854483, 5921351, 1978568, 909973, 6367615, 633075, 134212, 6100799, 5289720, 6999421, 5907263, 3090639, 6978067, 8151288, 1695374, 1229703, 373611, 8402868, 1057262, 5981173, 2958733, 8504669, 5773954, 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7109199, 8258966, 3298778, 981726, 9946117, 3122305, 3287999, 2456304, 7318902, 9530943, 1372013, 4727133, 6779098, 9271354, 3947092, 4234888, 5542704, 7888475, 2107567, 8850481, 4655367, 9257864, 1059088, 3242205, 5570208, 2803919, 7772073, 9121658, 8601590, 667305, 8836860, 2096212, 258363, 2342738, 7323328, 1191188, 3804067, 1374712, 6033107) and (products_ordered>0 OR products_viewed>1000) order by rand() limit 8[TEP STOP]2006 - MySQL server has gone awayselect count(*) as total from sessions where sesskey = 'ih6d7pc17ul8ql3nvj5koqlce8'[TEP STOP]