NP_055495.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
protein KIAA0100 isoform 1
NCBI Official Synonym Full Names
KIAA0100
NCBI Protein Information
protein KIAA0100
UniProt Protein Name
Protein KIAA0100
UniProt Synonym Protein Names
Antigen MLAA-22; Breast cancer-overexpressed gene 1 protein
UniProt Synonym Gene Names
NCBI Summary for K0100
This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017]
UniProt Comments for K0100
May be involved in membrane trafficking.
Research Articles on K0100
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Diseases associated with anti-K0100 antibody
Organs/Tissues associated with anti-K0100 antibody
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