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anti-KLF7 antibody :: Rabbit anti-Human, Mouse KLF7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9407437
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KLF7, Polyclonal Antibody

★Popular Item★
 Also Known As   

KLF7 Antibody

 Product Synonym Names    UKLF
 Product Gene Name   

anti-KLF7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604865
 3D Structure    ModBase 3D Structure for O75840
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    The antibody detects endogenous levels of total KLF7 protein.
 Purity/Purification    Antigen affinity purification.
 Form/Format    Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
 Concentration    2.9 mg/ml (lot specific)
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 Immunogen Type    Recombinant Protein
 Immunogen Description    Full length fusion protein
 Target Name    KLF7
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 Preparation and Storage    Store at -20 degree C
 Other Notes    Small volumes of anti-KLF7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-KLF7 antibody

   The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
 Product Categories/Family for anti-KLF7 antibody    Total protein Ab
 Applications Tested/Suitable for anti-KLF7 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-KLF7 antibody    Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
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 Testing Data of anti-KLF7 antibody    Gel: 8%SDS-PAGE Lysates (from left to right): Humna colon cancer and mouse kidney tissue, mouse testis and human fetal brain tissue Amount of lysate: 40ug per lane Primary antibody: 1/483.3 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds
anti-KLF7 antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-KLF7 antibody    Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.
anti-KLF7 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for KLF7. It may not necessarily be applicable to this product.
 NCBI GI #    401709918
 NCBI GeneID    8609
 NCBI Accession #    NP_001257871.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001270942.1 [Other Products]
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 UniProt Primary Accession #    O75840 [Other Products]
 UniProt Secondary Accession #    Q7Z3H8; Q96E51; B2RB03; B7Z4F7; C9JF04; E7EWH1; L0R4P2 [Other Products]
 UniProt Related Accession #    O75840 [Other Products]
 Molecular Weight    33kd
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 NCBI Official Full Name    Krueppel-like factor 7 isoform 2
 NCBI Official Synonym Full Names    Kruppel-like factor 7 (ubiquitous)
 NCBI Official Symbol    KLF7 [Similar Products]
 NCBI Official Synonym Symbols   
UKLF
[Similar Products]
 NCBI Protein Information    Krueppel-like factor 7
 UniProt Protein Name    Krueppel-like factor 7
 UniProt Synonym Protein Names   
Ubiquitous krueppel-like factor
 Protein Family    Krueppel-like factor
 UniProt Gene Name    KLF7 [Similar Products]
 UniProt Synonym Gene Names    UKLF [Similar Products]
 UniProt Entry Name    KLF7_HUMAN
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 NCBI Summary for KLF7    The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
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 UniProt Comments for KLF7    KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 2q32

Cellular Component: nucleus

Molecular Function: DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; dendrite morphogenesis
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 Research Articles on KLF7    1. a dominant mutation in FBXO38 causes adult-onset, progressive spinal muscular atrophy with calf predominance
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-KLF7 antibodyPathways associated with anti-KLF7 antibody
 Reference Product  PubMed Publications
 FBXO38 antibody  >1 publications with KLF7 and FBXO38
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
Diseases associated with anti-KLF7 antibodyOrgans/Tissues associated with anti-KLF7 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with KLF7 and Nervous System Diseases
 Atrophy Antibodies  >1 publications with KLF7 and Atrophy
 Neoplasms, Experimental Antibodies  >1 publications with KLF7 and Neoplasms, Experimental
 Heart Diseases Antibodies  >1 publications with KLF7 and Heart Diseases
 Fibrosis Antibodies  >1 publications with KLF7 and Fibrosis
 Cardiovascular Diseases Antibodies  >1 publications with KLF7 and Cardiovascular Diseases
 Hyperplasia Antibodies  >1 publications with KLF7 and Hyperplasia
 Learning Disorders Antibodies  >1 publications with KLF7 and Learning Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with KLF7 and Brain
 Embryonic Tissue Antibodies  >5 publications with KLF7 and Embryonic Tissue
 Connective Tissue Antibodies  >4 publications with KLF7 and Connective Tissue
 Muscle Antibodies  >4 publications with KLF7 and Muscle
 Blood Antibodies  >3 publications with KLF7 and Blood
 Kidney Antibodies  >2 publications with KLF7 and Kidney
 Vascular Antibodies  >2 publications with KLF7 and Vascular
 Lung Antibodies  >1 publications with KLF7 and Lung
 Placenta Antibodies  >1 publications with KLF7 and Placenta
 Mouth Antibodies  >1 publications with KLF7 and Mouth
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