Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow KLK7 rightarrow Polyclonal KLK7  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ADCYAP1R1 Antibody
 • DNA repair protein RAD51 homolog 4 (Rad51d) Recombinant Protein
 • Albumin ELISA Kit
 • Serine-threonine-protein kinase B-raf (BRAF) ELISA Kit
 • Enoyl-[acyl-carrier-protein ] reductase [NADH] (inhA) Recombinant Protein
 • collagen, type V, alpha 1 (COL5A1) ELISA Kit
 • MC2R Antibody
 • RANTES (CCL5) Recombinant Protein
 • TACI (TNFRSF13B) Antibody
 • laminin, alpha 1 (LAMA1) ELISA Kit
 • Melanocortin receptor 4 (MC4R) ELISA Kit
 • EDG1 Antibody
 • p-hydroxybenzoic acid efflux pump subunit AaeA (aaeA) Recombinant Protein
 • Pulmonary surfatcant-associated protein B, SP-B ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-KLK7 antibody :: Rabbit anti-Human KLK7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS855423
Testing Data
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KLK7, Polyclonal Antibody

 Also Known As   

KLK7 Antibody

 Product Gene Name   

anti-KLK7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    604438
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Form/Format    Lyophilized anti-KLK7 antibody purified by peptide affinity column containing 2% BSA and 0.02% NaN3
 Concentration    100ug/200ul (lot specific)
Section Bar
 Source Note    Rabbit polyclonal KLK7 (1) antibody was raised against a peptide near intermediate residues of human KLK7.
 Reactivity Note    Not yet tested in other species.
Section Bar
 Other Notes    Small volumes of anti-KLK7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-KLK7 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-KLK7 antibody   

Western Blot (WB)

 Application Notes for anti-KLK7 antibody    Peptide ELISA titer: 1:10,000-1:80,000
Western blot analysis: 1:200-1,000
Optimal dilutions/concentrations should be determined by the end use
Section Bar
 Testing Data of anti-KLK7 antibody    anti-KLK7 antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for KLK7. It may not necessarily be applicable to this product.
 NCBI GI #    21327705
 NCBI GeneID    5650
 NCBI Accession #    NP_644806 [Other Products]
 NCBI GenBank Nucleotide #    NM_139277.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q8N5N9; Q8NFV7; A8K0U5 [Other Products]
 UniProt Related Accession #    P49862 [Other Products]
 Molecular Weight    19,887 Da
Table BarTOPTable Bar
 NCBI Official Full Name    kallikrein-7 isoform 1 preproprotein
 NCBI Official Synonym Full Names    kallikrein-related peptidase 7
 NCBI Official Symbol    KLK7 [Similar Products]
 NCBI Official Synonym Symbols   
hK7; SCCE; PRSS6
[Similar Products]
 NCBI Protein Information    kallikrein-7; signal protein; serine protease 6; stratum corneum chymotryptic enzyme; kallikrein 7 (chymotryptic, stratum corneum)
 UniProt Protein Name    Kallikrein-7
 UniProt Synonym Protein Names   
Serine protease 6; Stratum corneum chymotryptic enzyme; hSCCE
 Protein Family    Kallikrein
 UniProt Gene Name    KLK7 [Similar Products]
 UniProt Synonym Gene Names    PRSS6; SCCE; hK7; hSCCE [Similar Products]
 UniProt Entry Name    KLK7_HUMAN
Section Bar
 NCBI Summary for KLK7    This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
Section Bar
 UniProt Comments for KLK7    KLK7: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.21.35

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: extracellular region

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: extracellular matrix disassembly; epidermis development; extracellular matrix organization and biogenesis; proteolysis
Table BarTOPTable Bar
 

Product References and Citations for anti-KLK7 antibody

   (1) Talieri,M., Mathioudaki,K., Prezas,P., et al. Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer. Thromb. Haemost. 101 (4), 741-747 (2009)
Section Bar
 Research Articles on KLK7    1. KLK7 and KLK14 gene expression can be regarded as markers of poor prognosis for colorectal cancer patients with discriminating power between CC and adenoma patients.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products related to KLK7 Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS9402892  KLK7 Antibody  MBS4150435  Anti-KLK7 Antibody
 MBS2015073  FITC-linked Antibody to Kallikrein 7 (KLK7)  MBS2523525  KLK7 Antibody
 MBS2060517  APC-Linked Polyclonal Antibody to Kallikrein 7 (KLK7)  MBS2002657  Polyclonal Antibody to Kallikrein 7 (KLK7)
 MBS2004306  Biotin-Linked Antibody to Kallikrein 7 (KLK7)  MBS2060527  APC-Linked Polyclonal Antibody to Kallikrein 7 (KLK7)
 MBS9127840  KLK7 Polyclonal Antibody  MBS2060525  APC/CY7-Linked Polyclonal Antibody to Kallikrein 7 (KLK7)
Products associated with anti-KLK7 antibodyPathways associated with anti-KLK7 antibody
 Reference Product  PubMed Publications
 KLK5 antibody  >70 publications with KLK7 and KLK5
 KLK8 antibody  >27 publications with KLK7 and KLK8
 SPINK5 antibody  >23 publications with KLK7 and SPINK5
 KLK10 antibody  >14 publications with KLK7 and KLK10
 DSG1 antibody  >11 publications with KLK7 and DSG1
 CDSN antibody  >8 publications with KLK7 and CDSN
 A2ML1 antibody  >2 publications with KLK7 and A2ML1
 Products by Pathway  Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with anti-KLK7 antibodyOrgans/Tissues associated with anti-KLK7 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >17 publications with KLK7 and Inflammation
 Genital Neoplasms, Female Antibodies  >16 publications with KLK7 and Genital Neoplasms, Female
 Ovarian Neoplasms Antibodies  >15 publications with KLK7 and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >13 publications with KLK7 and Adenocarcinoma
 Carcinoma, Squamous Cell Antibodies  >8 publications with KLK7 and Carcinoma, Squamous Cell
 Breast Neoplasms Antibodies  >8 publications with KLK7 and Breast Neoplasms
 Hyperplasia Antibodies  >5 publications with KLK7 and Hyperplasia
 Lung Diseases Antibodies  >4 publications with KLK7 and Lung Diseases
 Disease Models, Animal Antibodies  >4 publications with KLK7 and Disease Models, Animal
 Lung Neoplasms Antibodies  >4 publications with KLK7 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >104 publications with KLK7 and Skin
 Prostate Antibodies  >12 publications with KLK7 and Prostate
 Mouth Antibodies  >7 publications with KLK7 and Mouth
 Pancreas Antibodies  >7 publications with KLK7 and Pancreas
 Brain Antibodies  >7 publications with KLK7 and Brain
 Ovary Antibodies  >6 publications with KLK7 and Ovary
 Lung Antibodies  >4 publications with KLK7 and Lung
 Lymph Node Antibodies  >4 publications with KLK7 and Lymph Node
 Kidney Antibodies  >3 publications with KLK7 and Kidney
 Mammary Gland Antibodies  >3 publications with KLK7 and Mammary Gland
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions