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anti-KLK7 antibody :: Rabbit anti-Human KLK7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS855423
Testing Data
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KLK7, Polyclonal Antibody

 Also Known As   

KLK7 Antibody

 Product Gene Name   

anti-KLK7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604438
 3D Structure    ModBase 3D Structure for P49862
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Purified by peptide affinity column containing 2% BSA and 0.02% NaN3
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-KLK7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-KLK7 antibody

   Rabbit polyclonal KLK7 (1) antibody was raised against a peptide near intermediate residues of human KLK7.
 Product Categories/Family for anti-KLK7 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-KLK7 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-KLK7 antibody    Peptide ELISA: 1:10,000-1:80,000
WB: 1:200-1,000
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 Testing Data of anti-KLK7 antibody    anti-KLK7 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for KLK7. It may not necessarily be applicable to this product.
 NCBI GI #    21327705
 NCBI GeneID    5650
 NCBI Accession #    NP_644806 [Other Products]
 NCBI GenBank Nucleotide #    NM_139277.2 [Other Products]
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 UniProt Primary Accession #    P49862 [Other Products]
 UniProt Secondary Accession #    Q8N5N9; Q8NFV7; A8K0U5 [Other Products]
 UniProt Related Accession #    P49862 [Other Products]
 Molecular Weight    19,887 Da
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 NCBI Official Full Name    kallikrein-7 isoform 1 preproprotein
 NCBI Official Synonym Full Names    kallikrein related peptidase 7
 NCBI Official Symbol    KLK7 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    kallikrein-7
 UniProt Protein Name    Kallikrein-7
 UniProt Synonym Protein Names   
Serine protease 6; Stratum corneum chymotryptic enzyme; hSCCE
 Protein Family    Kallikrein
 UniProt Gene Name    KLK7 [Similar Products]
 UniProt Synonym Gene Names    PRSS6; SCCE; hK7; hSCCE [Similar Products]
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 NCBI Summary for KLK7    This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
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 UniProt Comments for KLK7    May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
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Product References and Citations for anti-KLK7 antibody

   (1) Talieri, M., Mathioudaki, K., Prezas, P., et al. Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer. Thromb. Haemost. 101 (4), 741-747 (2009).
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 Research Articles on KLK7    1. KLK7 is differentially expressed in lesional biopsy specimens from patients with atopic eczema relative to normal skin
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-KLK7 antibodyPathways associated with anti-KLK7 antibody
 Reference Product  PubMed Publications
 SPINK5 antibody  >25 publications with KLK7 and SPINK5
 DSG1 antibody  >11 publications with KLK7 and DSG1
 CDSN antibody  >8 publications with KLK7 and CDSN
 DSC1 antibody  >7 publications with KLK7 and DSC1
 FLG antibody  >5 publications with KLK7 and FLG
 SPINK9 antibody  >4 publications with KLK7 and SPINK9
 A2ML1 antibody  >2 publications with KLK7 and A2ML1
 Products by Pathway  Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with anti-KLK7 antibodyOrgans/Tissues associated with anti-KLK7 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >21 publications with KLK7 and Inflammation
 Breast Neoplasms Antibodies  >8 publications with KLK7 and Breast Neoplasms
 Congenital Abnormalities Antibodies  >8 publications with KLK7 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >5 publications with KLK7 and Disease Models, Animal
 Neoplasm Invasiveness Antibodies  >5 publications with KLK7 and Neoplasm Invasiveness
 Hyperplasia Antibodies  >5 publications with KLK7 and Hyperplasia
 Lung Neoplasms Antibodies  >4 publications with KLK7 and Lung Neoplasms
 Uterine Cervical Neoplasms Antibodies  >4 publications with KLK7 and Uterine Cervical Neoplasms
 Neoplasms, Experimental Antibodies  >4 publications with KLK7 and Neoplasms, Experimental
 Lung Diseases Antibodies  >4 publications with KLK7 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >113 publications with KLK7 and Skin
 Prostate Antibodies  >13 publications with KLK7 and Prostate
 Mouth Antibodies  >8 publications with KLK7 and Mouth
 Pancreas Antibodies  >7 publications with KLK7 and Pancreas
 Brain Antibodies  >7 publications with KLK7 and Brain
 Ovary Antibodies  >6 publications with KLK7 and Ovary
 Lymph Node Antibodies  >6 publications with KLK7 and Lymph Node
 Lung Antibodies  >4 publications with KLK7 and Lung
 Kidney Antibodies  >3 publications with KLK7 and Kidney
 Mammary Gland Antibodies  >3 publications with KLK7 and Mammary Gland
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