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anti-KX antibody :: Rabbit anti-Human KX / XK Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS241098
Unit / Price
0.05 mg  /  $495 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KX / XK, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human KX / XK

 Product Synonym Names    Anti-KX / XK Antibody (aa409-425) IHC-plus; XK; KX; Kell complex 37 kDa component; Kx antigen; MCLDS; Membrane transport protein XK; X1k; XK-related protein 1; XKR1; XRG1; Human KX; XK
 Product Gene Name   

anti-KX antibody

[Similar Products]
 Product Synonym Gene Name    XK [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    phenotype 314850
 3D Structure    ModBase 3D Structure for P51811
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Amino acids 409 to 425 of human XK
 Purity/Purification    Protein G Purified
 Form/Format    PBS, 0.09% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human XK.
 Immunogen Type    Synthetic peptide
 Immunogen    KX / XK antibody was raised against synthetic peptide from human XK.
 Antigen Modification    aa409-425
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 Preparation and Storage    Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
 Other Notes    Small volumes of anti-KX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-KX antibody    Family: Transporter
Subfamily: KX Blood-group Antigen
 Applications Tested/Suitable for anti-KX antibody   

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

 Application Notes for anti-KX antibody    ELISA (1:000 - 1:1000), IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
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 Immunohistochemistry (IHC) of anti-KX antibody    Anti-XK antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-KX antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-KX antibody    Anti-XK antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-KX antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for KX. It may not necessarily be applicable to this product.
 NCBI GI #    10835267
 NCBI GeneID    7504
 NCBI Accession #    NP_066569.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021083.2 [Other Products]
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 UniProt Primary Accession #    P51811 [Other Products]
 UniProt Secondary Accession #    Q4TTN6; Q8IUK6; Q9UC77 [Other Products]
 UniProt Related Accession #    P51811 [Other Products]
 Molecular Weight    50,902 Da
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 NCBI Official Full Name    membrane transport protein XK
 NCBI Official Synonym Full Names    X-linked Kx blood group
 NCBI Official Symbol    XK [Similar Products]
 NCBI Official Synonym Symbols   
KX; NA; NAC; X1k; XKR1; MCLDS
[Similar Products]
 NCBI Protein Information    membrane transport protein XK; Kx antigen; neurocanthocytosis; neuroacanthocytosis; XK-related protein 1; kell complex 37 kDa component; Kell blood group precursor (McLeod phenotype); XK, Kell blood group complex subunit (McLeod syndrome)
 UniProt Protein Name    Membrane transport protein XK
 UniProt Synonym Protein Names   
Kell complex 37 kDa component; Kx antigen; XK-related protein 1
 UniProt Gene Name    XK [Similar Products]
 UniProt Synonym Gene Names    XKR1; XRG1 [Similar Products]
 UniProt Entry Name    XK_HUMAN
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 NCBI Summary for KX    This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KX    XK: May be involved in sodium-dependent transport of neutral amino acids or oligopeptides. Defects in XK are the cause of McLeod syndrome (MLS). It is an X-linked multisystem disorder characterized by late onset abnormalities in the neuromuscular and hematopoietic systems. Belongs to the XK family.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xp21.1

Cellular Component: integral to membrane

Molecular Function: protein binding; transporter activity

Biological Process: myelination; cellular calcium ion homeostasis; transport; amino acid transport; regulation of axon diameter; skeletal muscle fiber development; regulation of cell size

Disease: Mcleod Syndrome
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 Research Articles on KX    1. Novel XK protein mutations are reported in two patients who exhibit typical clinical characteristics of McLeod syndrome.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Rabbit Polyclonal to Human KX / XK
 Catalog #  Product Name  Catalog #  Product Name
 MBS242373  Rabbit Polyclonal to Human KX / XK  MBS241098  Rabbit Polyclonal to Human KX / XK
Products associated with anti-KX antibodyDiseases associated with anti-KX antibody
 Reference Product  PubMed Publications
 KEL antibody  >11 publications with KX and KEL
 CYBB antibody  >9 publications with KX and CYBB
 VPS13A antibody  >7 publications with KX and VPS13A
 Disease Name  Pubmed Publications
 Movement Disorders Antibodies  >35 publications with KX and Movement Disorders
 Neuroacanthocytosis Antibodies  >32 publications with KX and Neuroacanthocytosis
 Hematologic Diseases Antibodies  >29 publications with KX and Hematologic Diseases
 Neuromuscular Diseases Antibodies  >23 publications with KX and Neuromuscular Diseases
 Congenital Abnormalities Antibodies  >17 publications with KX and Congenital Abnormalities
 Abnormalities, Multiple Antibodies  >12 publications with KX and Abnormalities, Multiple
 Disease Models, Animal Antibodies  >8 publications with KX and Disease Models, Animal
 Mental Disorders Antibodies  >7 publications with KX and Mental Disorders
 Heart Diseases Antibodies  >7 publications with KX and Heart Diseases
 Neural Tube Defects Antibodies  >5 publications with KX and Neural Tube Defects
Organs/Tissues associated with anti-KX antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >116 publications with KX and Blood
 Brain Antibodies  >36 publications with KX and Brain
 Muscle Antibodies  >27 publications with KX and Muscle
 Heart Antibodies  >14 publications with KX and Heart
 Liver Antibodies  >11 publications with KX and Liver
 Nerve Antibodies  >10 publications with KX and Nerve
 Testis Antibodies  >5 publications with KX and Testis
 Eye Antibodies  >4 publications with KX and Eye
 Intestine Antibodies  >3 publications with KX and Intestine
 Stomach Antibodies  >2 publications with KX and Stomach
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