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anti-KLK5 antibody :: Rabbit Kallikrein 5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS175442
Unit / Price
0.1 mg  /  $245 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Kallikrein 5 (KLK5), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-Kallikrein 5 antibody

 Product Synonym Names    Kallikrein related-peptidase 5/Protein Klk5; kallikrein-related peptidase 5; HK5 antibody; Kallikrein 5 antibody; Kallikrein L2 antibody; Kallikrein Like 2 antibody; Kallikrein like protein 2 antibody; Kallikrein related peptidase 5 antibody; Kallikrein-5 antibody; Kallikrein-like protein 2 antibody; Kallikrein5 antibody; KLK 5 antibody; KLK L2 antibody; KLK-L2 antibody; KLK5 antibody; KLK5_HUMAN antibody; KLKL 2 antibody; KLKL2 antibody; SCTE antibody; Stratum Corneum Tryptic Enzyme antibody; UNQ570/PRO1132 antibody
 Product Gene Name   

anti-KLK5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9D140
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse, Rat
No cross reactivity with other proteins.
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 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 5 (278-293aa NLCEFVKWIKDTMNSN), different from the related rat sequence by three amino acids.
 Contents    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-KLK5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-KLK5 antibody

   Description: Rabbit IgG polyclonal antibody for Kallikrein related-peptidase 5/Protein Klk5(KLK5) detection. Tested with WB, IHC-P in Mouse, Rat.
Background: KLK5(Kallikrein-related peptidase 5), formerly known as stratum corneum tryptic enzyme(SCTE) or KLKL2, is a serine protease expressed in the epidermis. The KLK5 gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.
 Applications Tested/Suitable for anti-KLK5 antibody   

Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)

 Application Notes for anti-KLK5 antibody    WB:
Concentration: 0.1-0.5ug/ml
Tested Species: Ms

IHC-P:
0.5-1ug/ml
Tested Species: Rat
Concluded Species: Ms
Antigen Retrieval: By Heat.

Other applications have not been tested.
Optimal dilutions should be determined by end user.
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 Western Blot (WB) of anti-KLK5 antibody    Anti-Kallikrein 5 antibody, MBS175442, Western blotting
WB: Mouse Liver Tissue Lysate
anti-KLK5 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-KLK5 antibody    Anti-Kallikrein 5 antibody, MBS175442, IHC(P)
IHC(P): Rat Testis Tissue
anti-KLK5 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for KLK5. It may not necessarily be applicable to this product.
 NCBI GI #    81916936
 NCBI Accession #    Q9D140 [Other Products]
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 UniProt Primary Accession #    Q9D140 [Other Products]
 Molecular Weight    31,908 Da
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 NCBI Official Full Name    18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1110030O19 product:similar to Kallikrein 5
 UniProt Protein Name    Kallikrein 1-related peptidase b5
 UniProt Synonym Protein Names   
Kallikrein 1-related peptidase b5
 Protein Family    Kallikrein
 UniProt Gene Name    Klk5 [Similar Products]
 UniProt Entry Name    Q9D140_MOUSE
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 UniProt Comments for KLK5    KLK5: May be involved in desquamation. Belongs to the peptidase S1 family. Kallikrein subfamily.

Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide

Cellular Component: extracellular space

Molecular Function: peptidase activity; serine-type endopeptidase activity

Biological Process: positive regulation of antibacterial peptide production; positive regulation of G-protein coupled receptor protein signaling pathway
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-KLK5 antibodyDiseases associated with anti-KLK5 antibody
 Reference Product  PubMed Publications
 Klk7 antibody  >70 publications with KLK5 and Klk7
 Disease Name  Pubmed Publications
 Dermatitis Antibodies  >21 publications with KLK5 and Dermatitis
 Inflammation Antibodies  >20 publications with KLK5 and Inflammation
 Breast Neoplasms Antibodies  >18 publications with KLK5 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >10 publications with KLK5 and Prostatic Neoplasms
 Necrosis Antibodies  >4 publications with KLK5 and Necrosis
 Nervous System Diseases Antibodies  >2 publications with KLK5 and Nervous System Diseases
 Kidney Diseases Antibodies  >2 publications with KLK5 and Kidney Diseases
 Nerve Degeneration Antibodies  >1 publications with KLK5 and Nerve Degeneration
 Vascular Diseases Antibodies  >1 publications with KLK5 and Vascular Diseases
 Cardiovascular Diseases Antibodies  >1 publications with KLK5 and Cardiovascular Diseases
Organs/Tissues associated with anti-KLK5 antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >3 publications with KLK5 and Embryonic Tissue
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